Search details
1.
Discovery of new enzymes and metabolic pathways by using structure and genome context.
Nature
; 502(7473): 698-702, 2013 Oct 31.
Article
in English
| MEDLINE | ID: mdl-24056934
2.
Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus.
Proc Natl Acad Sci U S A
; 112(18): 5661-6, 2015 May 05.
Article
in English
| MEDLINE | ID: mdl-25901324
3.
Panoramic view of a superfamily of phosphatases through substrate profiling.
Proc Natl Acad Sci U S A
; 112(16): E1974-83, 2015 Apr 21.
Article
in English
| MEDLINE | ID: mdl-25848029
4.
Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.
PLoS Biol
; 12(4): e1001843, 2014 Apr.
Article
in English
| MEDLINE | ID: mdl-24756107
5.
Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase.
J Am Chem Soc
; 138(3): 826-36, 2016 Jan 27.
Article
in English
| MEDLINE | ID: mdl-26714575
6.
Homologue structure of the SLAC1 anion channel for closing stomata in leaves.
Nature
; 467(7319): 1074-80, 2010 Oct 28.
Article
in English
| MEDLINE | ID: mdl-20981093
7.
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc Natl Acad Sci U S A
; 110(13): E1196-202, 2013 Mar 26.
Article
in English
| MEDLINE | ID: mdl-23493556
8.
Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry
; 54(3): 909-31, 2015 Jan 27.
Article
in English
| MEDLINE | ID: mdl-25540822
9.
Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins
; 83(12): 2124-36, 2015 Dec.
Article
in English
| MEDLINE | ID: mdl-26033498
10.
Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc Natl Acad Sci U S A
; 109(11): 4122-7, 2012 Mar 13.
Article
in English
| MEDLINE | ID: mdl-22392983
11.
Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1.
Biochemistry
; 53(20): 3357-66, 2014 May 27.
Article
in English
| MEDLINE | ID: mdl-24831290
12.
l-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota.
Biochemistry
; 53(28): 4661-70, 2014 Jul 22.
Article
in English
| MEDLINE | ID: mdl-24963813
13.
Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily.
Biochemistry
; 53(3): 591-600, 2014 Jan 28.
Article
in English
| MEDLINE | ID: mdl-24401123
14.
Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup.
Biochemistry
; 53(16): 2722-31, 2014 Apr 29.
Article
in English
| MEDLINE | ID: mdl-24697546
15.
Functional annotation and structural characterization of a novel lactonase hydrolyzing D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate.
Biochemistry
; 53(28): 4727-38, 2014 Jul 22.
Article
in English
| MEDLINE | ID: mdl-24955762
16.
Crystal structure of human Karyopherin ß2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
J Struct Funct Genomics
; 14(2): 31-5, 2013 Jun.
Article
in English
| MEDLINE | ID: mdl-23535894
17.
Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins.
Biochemistry
; 52(6): 1101-12, 2013 Feb 12.
Article
in English
| MEDLINE | ID: mdl-23327428
18.
Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.
Biochemistry
; 52(1): 239-53, 2013 Jan 08.
Article
in English
| MEDLINE | ID: mdl-23214453
19.
Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes.
Biochemistry
; 52(37): 6525-36, 2013 Sep 17.
Article
in English
| MEDLINE | ID: mdl-23972005
20.
Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking.
J Am Chem Soc
; 135(2): 795-803, 2013 Jan 16.
Article
in English
| MEDLINE | ID: mdl-23256477