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1.
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
Proc Natl Acad Sci U S A
; 120(1): e2211297120, 2023 01 03.
Article
in English
| MEDLINE | ID: mdl-36574664
2.
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Mol Cell
; 58(3): 440-52, 2015 May 07.
Article
in English
| MEDLINE | ID: mdl-25818646
3.
WDR5 is a conserved regulator of protein synthesis gene expression.
Nucleic Acids Res
; 48(6): 2924-2941, 2020 04 06.
Article
in English
| MEDLINE | ID: mdl-31996893
4.
The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B.
Nucleic Acids Res
; 42(17): 10975-86, 2014.
Article
in English
| MEDLINE | ID: mdl-25183520
5.
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.
bioRxiv
; 2024 Jan 10.
Article
in English
| MEDLINE | ID: mdl-37546802
6.
WIN site inhibition disrupts a subset of WDR5 function.
Sci Rep
; 12(1): 1848, 2022 02 03.
Article
in English
| MEDLINE | ID: mdl-35115608
7.
Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells.
NAR Cancer
; 4(1): zcac007, 2022 Mar.
Article
in English
| MEDLINE | ID: mdl-35252869
8.
Inhibition of MYC by the SMARCB1 tumor suppressor.
Nat Commun
; 10(1): 2014, 2019 05 01.
Article
in English
| MEDLINE | ID: mdl-31043611
9.
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep
; 26(11): 2916-2928.e13, 2019 03 12.
Article
in English
| MEDLINE | ID: mdl-30865883
10.
Letter to the editor. Chemical-genetic strategy for inhibiting proteasome function in Saccharomyces cerevisiae.
Yeast
; 29(2): 93-4, 2012 Feb.
Article
in English
| MEDLINE | ID: mdl-22162073
11.
Interaction of Gcn4 with target gene chromatin is modulated by proteasome function.
Mol Biol Cell
; 27(17): 2735-41, 2016 09 01.
Article
in English
| MEDLINE | ID: mdl-27385344
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