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1.
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol.
Angew Chem Int Ed Engl
; 63(6): e202313859, 2024 Feb 05.
Article
in English
| MEDLINE | ID: mdl-38055195
2.
Discovery of an insulin-induced gene binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting sterol regulatory element-binding protein-mediated lipogenesis.
Hepatology
; 76(5): 1466-1481, 2022 11.
Article
in English
| MEDLINE | ID: mdl-35102596
3.
Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase.
PLoS Genet
; 15(7): e1008289, 2019 07.
Article
in English
| MEDLINE | ID: mdl-31323021
4.
Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol.
Eur J Med Chem
; 236: 114323, 2022 Jun 05.
Article
in English
| MEDLINE | ID: mdl-35397399
5.
Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol.
Nat Commun
; 9(1): 5138, 2018 12 03.
Article
in English
| MEDLINE | ID: mdl-30510211
6.
A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption.
Science
; 360(6393): 1087-1092, 2018 06 08.
Article
in English
| MEDLINE | ID: mdl-29880681
7.
Interferon-lambda3 (IFN-λ3) and its cognate receptor subunits in tree shrews (Tupaia belangeri): genomic sequence retrieval, molecular identification and expression analysis.
PLoS One
; 8(3): e60048, 2013.
Article
in English
| MEDLINE | ID: mdl-23555878
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