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1.
Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas.
Hum Mol Genet
; 33(11): 1001-1014, 2024 May 18.
Article
in English
| MEDLINE | ID: mdl-38483348
2.
Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes.
Diabetologia
; 66(12): 2226-2237, 2023 12.
Article
in English
| MEDLINE | ID: mdl-37798422
3.
The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity.
J Biol Chem
; 296: 100661, 2021.
Article
in English
| MEDLINE | ID: mdl-33862081
4.
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice.
Pancreatology
; 22(8): 1099-1111, 2022 Dec.
Article
in English
| MEDLINE | ID: mdl-36379850
5.
Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis.
Pancreatology
; 20(3): 377-384, 2020 Apr.
Article
in English
| MEDLINE | ID: mdl-32007358
6.
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants.
J Biol Chem
; 293(50): 19476-19491, 2018 12 14.
Article
in English
| MEDLINE | ID: mdl-30315106
7.
The role of the carboxyl ester lipase (CEL) gene in pancreatic disease.
Pancreatology
; 18(1): 12-19, 2018 Jan.
Article
in English
| MEDLINE | ID: mdl-29233499
8.
Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry.
Diabetologia
; 60(4): 625-635, 2017 04.
Article
in English
| MEDLINE | ID: mdl-27913849
9.
Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.
Pancreatology
; 17(1): 83-88, 2017.
Article
in English
| MEDLINE | ID: mdl-27773618
10.
Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction.
J Biol Chem
; 289(42): 29097-111, 2014 Oct 17.
Article
in English
| MEDLINE | ID: mdl-25160620
11.
Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young.
J Biol Chem
; 288(8): 5353-6, 2013 Feb 22.
Article
in English
| MEDLINE | ID: mdl-23306198
12.
SUMOylation of pancreatic glucokinase regulates its cellular stability and activity.
J Biol Chem
; 288(8): 5951-62, 2013 Feb 22.
Article
in English
| MEDLINE | ID: mdl-23297408
13.
In Vitro Functional Analysis Can Aid Precision Diagnostics of HNF1B-MODY.
J Mol Diagn
; 26(6): 530-541, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38575066
14.
GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation.
Biochim Biophys Acta
; 1822(11): 1705-15, 2012 Nov.
Article
in English
| MEDLINE | ID: mdl-22820548
15.
Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease.
J Biol Chem
; 286(40): 34593-605, 2011 Oct 07.
Article
in English
| MEDLINE | ID: mdl-21784842
16.
Gα(12) binds to the N-terminal regulatory domain of p120(ctn), and downregulates p120(ctn) tyrosine phosphorylation induced by Src family kinases via a RhoA independent mechanism.
Exp Cell Res
; 317(3): 293-306, 2011 Feb 01.
Article
in English
| MEDLINE | ID: mdl-20974127
17.
Abnormal exocrine-endocrine cell cross-talk promotes ß-cell dysfunction and loss in MODY8.
Nat Metab
; 4(1): 76-89, 2022 01.
Article
in English
| MEDLINE | ID: mdl-35058633
18.
Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases.
J Clin Endocrinol Metab
; 107(4): e1455-e1466, 2022 03 24.
Article
in English
| MEDLINE | ID: mdl-34850019
19.
Characterization of the genetic architecture of infant and early childhood body mass index.
Nat Metab
; 4(3): 344-358, 2022 03.
Article
in English
| MEDLINE | ID: mdl-35315439
20.
Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis.
Eur J Gastroenterol Hepatol
; 33(6): 839-843, 2021 06 01.
Article
in English
| MEDLINE | ID: mdl-33079780