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1.
A novel calcium channel Cavß2 splice variant with unique properties predominates in the retina.
J Biol Chem
; 299(4): 102972, 2023 04.
Article
in English
| MEDLINE | ID: mdl-36738788
2.
Development of heterodimeric estrogen receptor alpha antagonists to target simultaneously the ligand and coactivator binding site.
Arch Pharm (Weinheim)
; 356(7): e2200638, 2023 Jul.
Article
in English
| MEDLINE | ID: mdl-37173820
3.
De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder.
Am J Hum Genet
; 104(4): 709-720, 2019 04 04.
Article
in English
| MEDLINE | ID: mdl-30905399
4.
Novel CACNA1A Variant p.Cys256Phe Disrupts Disulfide Bonds and Causes Spinocerebellar Ataxia.
Mov Disord
; 37(2): 401-404, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34647648
5.
Correction to: De novo CACNA1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism.
Pflugers Arch
; 472(8): 1105, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32666275
6.
De novo CACNA1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism.
Pflugers Arch
; 472(7): 755-773, 2020 07.
Article
in English
| MEDLINE | ID: mdl-32583268
7.
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity.
Br J Cancer
; 123(4): 542-555, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32439931
8.
Steroid sulfatase inhibiting lanostane triterpenes - Structure activity relationship and in silico insights.
Bioorg Chem
; 95: 103495, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31855822
9.
Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17ß-Hydroxysteroid Dehydrogenases.
Int J Mol Sci
; 18(9)2017 Sep 19.
Article
in English
| MEDLINE | ID: mdl-28925944
10.
Optimized Virtual Screening Workflow for the Identification of Novel G-Quadruplex Ligands.
J Chem Inf Model
; 56(3): 484-500, 2016 Mar 28.
Article
in English
| MEDLINE | ID: mdl-26841201
11.
Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases.
Molecules
; 20(12): 22799-832, 2015 Dec 19.
Article
in English
| MEDLINE | ID: mdl-26703541
12.
Cav 1.3-selective inhibitors of voltage-gated L-type Ca2+ channels: Fact or (still) fiction?
Br J Pharmacol
; 180(10): 1289-1303, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36788128
13.
Protocol for predicting drug-resistant protein mutations to an ERK2 inhibitor using RESISTOR.
STAR Protoc
; 4(2): 102170, 2023 Apr 27.
Article
in English
| MEDLINE | ID: mdl-37115667
14.
Disruptor: Computational identification of oncogenic mutants disrupting protein-protein and protein-DNA interactions.
Commun Biol
; 6(1): 720, 2023 07 13.
Article
in English
| MEDLINE | ID: mdl-37443295
15.
A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
bioRxiv
; 2023 Oct 04.
Article
in English
| MEDLINE | ID: mdl-37808638
16.
RESISTOR: A New OSPREY Module to Predict Resistance Mutations.
J Comput Biol
; 29(12): 1346-1352, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36099194
17.
Resistor: An algorithm for predicting resistance mutations via Pareto optimization over multistate protein design and mutational signatures.
Cell Syst
; 13(10): 830-843.e3, 2022 10 19.
Article
in English
| MEDLINE | ID: mdl-36265469
18.
Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides.
Biomedicines
; 9(12)2021 Dec 11.
Article
in English
| MEDLINE | ID: mdl-34944698
19.
Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.
Sci Rep
; 10(1): 13804, 2020 08 14.
Article
in English
| MEDLINE | ID: mdl-32796875
20.
A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma.
Oncogene
; 39(5): 1080-1097, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31591479