Search details
1.
The translational challenge in Chagas disease drug development.
Mem Inst Oswaldo Cruz
; 117: e200501, 2022.
Article
in English
| MEDLINE | ID: mdl-35613156
2.
Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi.
Bioorg Med Chem Lett
; 30(1): 126779, 2020 01 01.
Article
in English
| MEDLINE | ID: mdl-31706667
3.
Chemical Constituents and Pharmacology properties of Aristolochia triangularis: a south brazilian highly-consumed botanical with multiple bioactivities.
An Acad Bras Cienc
; 91(3): e20180621, 2019 Aug 12.
Article
in English
| MEDLINE | ID: mdl-31411258
4.
Natural products modulating the hERG channel: heartaches and hope.
Nat Prod Rep
; 34(8): 957-980, 2017 08 02.
Article
in English
| MEDLINE | ID: mdl-28497823
5.
Enzymatic synthesis of ascorbyl ester derived from linoleic acid.
Bioprocess Biosyst Eng
; 40(2): 265-270, 2017 Feb.
Article
in English
| MEDLINE | ID: mdl-27752771
6.
Solid dispersions enhance solubility, dissolution, and permeability of thalidomide.
Drug Dev Ind Pharm
; 43(3): 511-518, 2017 Mar.
Article
in English
| MEDLINE | ID: mdl-27915573
7.
Rosmarinic Acid--Pharmaceutical and Clinical Aspects.
Planta Med
; 82(5): 388-406, 2016 Mar.
Article
in English
| MEDLINE | ID: mdl-26845712
8.
Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method.
Planta Med
; 82(11-12): 1030-8, 2016 Jul.
Article
in English
| MEDLINE | ID: mdl-27257769
9.
hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico - In Vitro Screening.
Planta Med
; 82(11-12): 1009-15, 2016 Jul.
Article
in English
| MEDLINE | ID: mdl-27145237
10.
Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools.
J Chem Inf Model
; 54(10): 2887-901, 2014 Oct 27.
Article
in English
| MEDLINE | ID: mdl-25148533
11.
Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus.
Eur J Med Chem
; 264: 116010, 2024 Jan 15.
Article
in English
| MEDLINE | ID: mdl-38104375
12.
Synthesis and Anti-Trypanosoma cruzi Activity of 3-Cyanopyridine Derivatives.
ACS Omega
; 9(20): 22360-22370, 2024 May 21.
Article
in English
| MEDLINE | ID: mdl-38799347
13.
Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.
Eur J Med Chem
; 246: 114925, 2023 Jan 15.
Article
in English
| MEDLINE | ID: mdl-36459758
14.
Preparation, characterization, and in vitro intestinal permeability evaluation of thalidomide-hydroxypropyl-ß-cyclodextrin complexes.
AAPS PharmSciTech
; 13(1): 118-24, 2012 Mar.
Article
in English
| MEDLINE | ID: mdl-22160886
15.
Chagas Disease Drug Discovery in Latin America-A Mini Review of Antiparasitic Agents Explored Between 2010 and 2021.
Front Chem
; 9: 771143, 2021.
Article
in English
| MEDLINE | ID: mdl-34778217
16.
2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profiling.
PLoS Negl Trop Dis
; 15(2): e0009196, 2021 02.
Article
in English
| MEDLINE | ID: mdl-33617566
17.
Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents.
RSC Med Chem
; 11(11): 1267-1274, 2020 Aug 25.
Article
in English
| MEDLINE | ID: mdl-34085041
18.
In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.
Front Chem
; 6: 242, 2018.
Article
in English
| MEDLINE | ID: mdl-30013964
19.
The translational challenge in Chagas disease drug development
Mem. Inst. Oswaldo Cruz
; 117: e200501, 2022. graf
Article
in English
|
LILACS-Express
| ID: biblio-1375909
20.
In vitro testing for genotoxicity of violacein assessed by Comet and Micronucleus assays.
Mutat Res
; 603(1): 97-103, 2006 Jan 31.
Article
in English
| MEDLINE | ID: mdl-16359912