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1.
Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.
Bioorg Med Chem Lett
; 25(4): 948-51, 2015 Feb 15.
Article
in English
| MEDLINE | ID: mdl-25577039
2.
Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C2-symmetric inhibitors with diyne and biphenyl linkers.
Bioorg Med Chem Lett
; 25(4): 936-9, 2015 Feb 15.
Article
in English
| MEDLINE | ID: mdl-25595681
3.
Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: non-symmetric inhibitors with potent activity against genotype 1a and 1b.
Bioorg Med Chem Lett
; 25(4): 940-3, 2015 Feb 15.
Article
in English
| MEDLINE | ID: mdl-25597006
4.
Benzimidazole-containing HCV NS5A inhibitors: effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency.
Bioorg Med Chem Lett
; 25(4): 944-7, 2015 Feb 15.
Article
in English
| MEDLINE | ID: mdl-25577041
5.
Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
J Med Chem
; 59(13): 6293-302, 2016 07 14.
Article
in English
| MEDLINE | ID: mdl-27366941
6.
Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.
J Med Chem
; 46(8): 1283-5, 2003 Apr 10.
Article
in English
| MEDLINE | ID: mdl-12672227
7.
Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors.
ACS Med Chem Lett
; 5(3): 240-3, 2014 Mar 13.
Article
in English
| MEDLINE | ID: mdl-24900811
8.
Docking ligands into flexible and solvated macromolecules. 2. Development and application of fitted 1.5 to the virtual screening of potential HCV polymerase inhibitors.
J Chem Inf Model
; 48(4): 902-9, 2008 Apr.
Article
in English
| MEDLINE | ID: mdl-18341269
9.
Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
Bioorg Med Chem Lett
; 13(19): 3341-4, 2003 Oct 06.
Article
in English
| MEDLINE | ID: mdl-12951122
10.
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
Bioorg Med Chem Lett
; 14(3): 793-6, 2004 Feb 09.
Article
in English
| MEDLINE | ID: mdl-14741291
11.
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.
Bioorg Med Chem Lett
; 14(3): 797-800, 2004 Feb 09.
Article
in English
| MEDLINE | ID: mdl-14741292
12.
HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.
Bioorg Med Chem Lett
; 14(21): 5333-7, 2004 Nov 01.
Article
in English
| MEDLINE | ID: mdl-15454222
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