Search details
1.
G-CSF drives autoinflammation in APLAID.
Nat Immunol
; 24(5): 814-826, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36997670
2.
RIP3 induces apoptosis independent of pronecrotic kinase activity.
Mol Cell
; 56(4): 481-95, 2014 Nov 20.
Article
in English
| MEDLINE | ID: mdl-25459880
3.
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.
Immunity
; 36(5): 742-54, 2012 May 25.
Article
in English
| MEDLINE | ID: mdl-22503542
4.
NLRX1 is a regulator of mitochondrial antiviral immunity.
Nature
; 451(7178): 573-7, 2008 Jan 31.
Article
in English
| MEDLINE | ID: mdl-18200010
5.
Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity.
J Biol Chem
; 287(30): 25030-7, 2012 Jul 20.
Article
in English
| MEDLINE | ID: mdl-22665479
6.
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.
J Immunol
; 185(8): 4515-9, 2010 Oct 15.
Article
in English
| MEDLINE | ID: mdl-20861349
7.
Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses.
Proc Natl Acad Sci U S A
; 105(35): 13015-20, 2008 Sep 02.
Article
in English
| MEDLINE | ID: mdl-18728195
8.
Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.
ACS Med Chem Lett
; 10(6): 857-862, 2019 Jun 13.
Article
in English
| MEDLINE | ID: mdl-31223438
9.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Article
in English
| MEDLINE | ID: mdl-31013427
10.
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell
; 34(5): 757-774.e7, 2018 11 12.
Article
in English
| MEDLINE | ID: mdl-30423296
11.
Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions.
Microbes Infect
; 9(5): 672-6, 2007 Apr.
Article
in English
| MEDLINE | ID: mdl-17418609
12.
Identification of an antibody-based immunoassay for measuring direct target binding of RIPK1 inhibitors in cells and tissues.
Pharmacol Res Perspect
; 5(6)2017 12.
Article
in English
| MEDLINE | ID: mdl-29226625
13.
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
J Med Chem
; 60(4): 1247-1261, 2017 02 23.
Article
in English
| MEDLINE | ID: mdl-28151659
14.
Criteria for effective design, construction, and gene knockdown by shRNA vectors.
BMC Biotechnol
; 6: 7, 2006 Jan 24.
Article
in English
| MEDLINE | ID: mdl-16433925
15.
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.
Cancer Res
; 63(20): 6928-34, 2003 Oct 15.
Article
in English
| MEDLINE | ID: mdl-14583493
16.
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell
; 38(4): 585-590, 2020 Oct 12.
Article
in English
| MEDLINE | ID: mdl-33049209
17.
Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.
PLoS One
; 8(4): e60842, 2013.
Article
in English
| MEDLINE | ID: mdl-23577168
18.
Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis.
ACS Med Chem Lett
; 4(12): 1238-43, 2013 Dec 12.
Article
in English
| MEDLINE | ID: mdl-24900635
19.
Characterization of NLRP12 during the development of allergic airway disease in mice.
PLoS One
; 7(1): e30612, 2012.
Article
in English
| MEDLINE | ID: mdl-22291998
20.
ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.
Mol Cell Biol
; 28(5): 1841-50, 2008 Mar.
Article
in English
| MEDLINE | ID: mdl-18160710