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1.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 179(2): 417-431.e19, 2019 Oct 03.
Article
in English
| MEDLINE | ID: mdl-31585081
2.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 180(2): 406, 2020 Jan 23.
Article
in English
| MEDLINE | ID: mdl-31978350
3.
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.
Biochem J
; 472(2): 169-81, 2015 Dec 01.
Article
in English
| MEDLINE | ID: mdl-26385991
4.
Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.
J Biol Chem
; 287(52): 43482-91, 2012 Dec 21.
Article
in English
| MEDLINE | ID: mdl-23135270
5.
Structural insight into distinct mechanisms of protease inhibition by antibodies.
Proc Natl Acad Sci U S A
; 104(50): 19784-9, 2007 Dec 11.
Article
in English
| MEDLINE | ID: mdl-18077410
6.
Bivalent antibody pliers inhibit ß-tryptase by an allosteric mechanism dependent on the IgG hinge.
Nat Commun
; 11(1): 6435, 2020 12 22.
Article
in English
| MEDLINE | ID: mdl-33353951
7.
Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.
FEBS Lett
; 579(9): 1945-50, 2005 Mar 28.
Article
in English
| MEDLINE | ID: mdl-15792801
8.
Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation.
J Mol Biol
; 331(2): 433-46, 2003 Aug 08.
Article
in English
| MEDLINE | ID: mdl-12888350
9.
Structural and functional analysis of HtrA1 and its subdomains.
Structure
; 20(6): 1040-50, 2012 Jun 06.
Article
in English
| MEDLINE | ID: mdl-22578544
10.
Unraveling the allosteric mechanism of serine protease inhibition by an antibody.
Structure
; 17(12): 1614-1624, 2009 Dec 09.
Article
in English
| MEDLINE | ID: mdl-20004165
11.
Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist.
Proc Natl Acad Sci U S A
; 104(13): 5306-11, 2007 Mar 27.
Article
in English
| MEDLINE | ID: mdl-17372204
12.
Similar molecular interactions of factor VII and factor VIIa with the tissue factor region that allosterically regulates enzyme activity.
Biochemistry
; 43(5): 1223-9, 2004 Feb 10.
Article
in English
| MEDLINE | ID: mdl-14756558
13.
Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling.
J Biol Chem
; 279(38): 39915-24, 2004 Sep 17.
Article
in English
| MEDLINE | ID: mdl-15218027
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