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1.
Discovery of a novel ROCK2 ATP competitive inhibitor by DNA-encoded library selection.
Biochem Biophys Res Commun
; 699: 149537, 2024 Mar 05.
Article
in English
| MEDLINE | ID: mdl-38280309
2.
The cancer control status and APACHE II score are prognostic factors for critically ill patients with cancer and sepsis.
J Formos Med Assoc
; 119(1 Pt 2): 276-281, 2020 Jan.
Article
in English
| MEDLINE | ID: mdl-31153724
3.
C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response.
J Biol Chem
; 293(27): 10561-10573, 2018 07 06.
Article
in English
| MEDLINE | ID: mdl-29802199
4.
Electrostatic Interactions between Hendra Virus Matrix Proteins Are Required for Efficient Virus-Like-Particle Assembly.
J Virol
; 92(13)2018 07 01.
Article
in English
| MEDLINE | ID: mdl-29695428
5.
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.
Bioorg Chem
; 86: 494-500, 2019 05.
Article
in English
| MEDLINE | ID: mdl-30780018
6.
The shaping of T cell receptor recognition by self-tolerance.
Immunity
; 30(2): 193-203, 2009 Feb 20.
Article
in English
| MEDLINE | ID: mdl-19167249
7.
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.
Immunity
; 30(6): 777-88, 2009 Jun 19.
Article
in English
| MEDLINE | ID: mdl-19464197
8.
Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay.
Bioorg Med Chem
; 26(8): 1751-1758, 2018 05 01.
Article
in English
| MEDLINE | ID: mdl-29534934
9.
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.
Bioorg Med Chem
; 26(20): 5397-5407, 2018 11 01.
Article
in English
| MEDLINE | ID: mdl-30297119
10.
Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors.
Bioorg Chem
; 78: 7-16, 2018 08.
Article
in English
| MEDLINE | ID: mdl-29524666
11.
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.
Molecules
; 23(3)2018 Mar 02.
Article
in English
| MEDLINE | ID: mdl-29498708
12.
Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays.
Bioorg Med Chem Lett
; 27(2): 342-346, 2017 01 15.
Article
in English
| MEDLINE | ID: mdl-27899265
13.
Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.
Org Biomol Chem
; 15(17): 3648-3661, 2017 May 03.
Article
in English
| MEDLINE | ID: mdl-28397890
14.
Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4.
J Chem Inf Model
; 57(7): 1677-1690, 2017 07 24.
Article
in English
| MEDLINE | ID: mdl-28636361
15.
Design and optimization of purine derivatives as in vivo active PDE10A inhibitors.
Bioorg Med Chem
; 25(13): 3315-3329, 2017 07 01.
Article
in English
| MEDLINE | ID: mdl-28462841
16.
A microfluidics-based mobility shift assay to identify new inhibitors of ß-secretase for Alzheimer's disease.
Anal Bioanal Chem
; 409(28): 6635-6642, 2017 Nov.
Article
in English
| MEDLINE | ID: mdl-28889204
17.
Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.
Bioorg Chem
; 72: 182-189, 2017 06.
Article
in English
| MEDLINE | ID: mdl-28460360
18.
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration.
Acta Pharmacol Sin
; 38(4): 551-560, 2017 Apr.
Article
in English
| MEDLINE | ID: mdl-28112184
19.
Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.
Bioorg Med Chem Lett
; 26(3): 721-725, 2016 Feb 01.
Article
in English
| MEDLINE | ID: mdl-26776360
20.
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays.
Bioorg Med Chem Lett
; 26(15): 3813-7, 2016 08 01.
Article
in English
| MEDLINE | ID: mdl-27289323