Search | VHL CLAP/WR-PAHO/WHO

1.

CNVs: harbingers of a rare variant revolution in psychiatric genetics.

Malhotra, Dheeraj; Sebat, Jonathan.

Cell ; 148(6): 1223-41, 2012 Mar 16.

Article in English | MEDLINE | ID: mdl-22424231

2.

Whole-genome sequencing in autism identifies hot spots for de novo germline mutation.

Michaelson, Jacob J; Shi, Yujian; Gujral, Madhusudan; Zheng, Hancheng; Malhotra, Dheeraj; Jin, Xin; Jian, Minghan; Liu, Guangming; Greer, Douglas; Bhandari, Abhishek; Wu, Wenting; Corominas, Roser; Peoples, Aine; Koren, Amnon; Gore, Athurva; Kang, Shuli; Lin, Guan Ning; Estabillo, Jasper; Gadomski, Therese; Singh, Balvindar; Zhang, Kun; Akshoomoff, Natacha; Corsello, Christina; McCarroll, Steven; Iakoucheva, Lilia M; Li, Yingrui; Wang, Jun; Sebat, Jonathan.

Cell ; 151(7): 1431-42, 2012 Dec 21.

Article in English | MEDLINE | ID: mdl-23260136

3.

Altered human oligodendrocyte heterogeneity in multiple sclerosis.

Jäkel, Sarah; Agirre, Eneritz; Mendanha Falcão, Ana; van Bruggen, David; Lee, Ka Wai; Knuesel, Irene; Malhotra, Dheeraj; Ffrench-Constant, Charles; Williams, Anna; Castelo-Branco, Gonçalo.

Nature ; 566(7745): 543-547, 2019 02.

Article in English | MEDLINE | ID: mdl-30747918

4.

Frequency and Complexity of De Novo Structural Mutation in Autism.

Brandler, William M; Antaki, Danny; Gujral, Madhusudan; Noor, Amina; Rosanio, Gabriel; Chapman, Timothy R; Barrera, Daniel J; Lin, Guan Ning; Malhotra, Dheeraj; Watts, Amanda C; Wong, Lawrence C; Estabillo, Jasper A; Gadomski, Therese E; Hong, Oanh; Fajardo, Karin V Fuentes; Bhandari, Abhishek; Owen, Renius; Baughn, Michael; Yuan, Jeffrey; Solomon, Terry; Moyzis, Alexandra G; Maile, Michelle S; Sanders, Stephan J; Reiner, Gail E; Vaux, Keith K; Strom, Charles M; Zhang, Kang; Muotri, Alysson R; Akshoomoff, Natacha; Leal, Suzanne M; Pierce, Karen; Courchesne, Eric; Iakoucheva, Lilia M; Corsello, Christina; Sebat, Jonathan.

Am J Hum Genet ; 98(4): 667-79, 2016 Apr 07.

Article in English | MEDLINE | ID: mdl-27018473

5.

Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.

Grochowski, Christopher M; Gu, Shen; Yuan, Bo; Tcw, Julia; Brennand, Kristen J; Sebat, Jonathan; Malhotra, Dheeraj; McCarthy, Shane; Rudolph, Uwe; Lindstrand, Anna; Chong, Zechen; Levy, Deborah L; Lupski, James R; Carvalho, Claudia M B.

Hum Mutat ; 39(7): 939-946, 2018 07.

Article in English | MEDLINE | ID: mdl-29696747

6.

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

Vacic, Vladimir; McCarthy, Shane; Malhotra, Dheeraj; Murray, Fiona; Chou, Hsun-Hua; Peoples, Aine; Makarov, Vladimir; Yoon, Seungtai; Bhandari, Abhishek; Corominas, Roser; Iakoucheva, Lilia M; Krastoshevsky, Olga; Krause, Verena; Larach-Walters, Verónica; Welsh, David K; Craig, David; Kelsoe, John R; Gershon, Elliot S; Leal, Suzanne M; Dell Aquila, Marie; Morris, Derek W; Gill, Michael; Corvin, Aiden; Insel, Paul A; McClellan, Jon; King, Mary-Claire; Karayiorgou, Maria; Levy, Deborah L; DeLisi, Lynn E; Sebat, Jonathan.

Nature ; 471(7339): 499-503, 2011 Mar 24.

Article in English | MEDLINE | ID: mdl-21346763

7.

Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals novel associations with AD pathology.

Gaur, Pallavi; Bryois, Julien; Calini, Daniela; Foo, Lynette; Hoozemans, Jeroen J M; Malhotra, Dheeraj; Menon, Vilas.

bioRxiv ; 2024 Apr 27.

Article in English | MEDLINE | ID: mdl-38712204

8.

Genetics: Fish heads and human disease.

Malhotra, Dheeraj; Sebat, Jonathan.

Nature ; 485(7398): 318-9, 2012 May 16.

Article in English | MEDLINE | ID: mdl-22596152

9.

A structured evaluation of cryopreservation in generating single-cell transcriptomes from cerebrospinal fluid.

Touil, Hanane; Roostaei, Tina; Calini, Daniela; Diaconu, Claudiu; Epstein, Samantha; Raposo, Catarina; Onomichi, Kaho; Thakur, Kiran T; Craveiro, Licinio; Callegari, Ilaria; Bryois, Julien; Riley, Claire S; Menon, Vilas; Derfuss, Tobias; De Jager, Philip L; Malhotra, Dheeraj.

Cell Rep Methods ; 3(7): 100533, 2023 07 24.

Article in English | MEDLINE | ID: mdl-37533636

10.

Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics.

Rexach, Jessica E; Cheng, Yuyan; Chen, Lawrence; Polioudakis, Damon; Lin, Li-Chun; Mitri, Vivianne; Elkins, Andrew; Yin, Anna; Calini, Daniela; Kawaguchi, Riki; Ou, Jing; Huang, Jerry; Williams, Christopher; Robinson, John; Gaus, Stephanie E; Spina, Salvatore; Lee, Edward B; Grinberg, Lea T; Vinters, Harry; Trojanowski, John Q; Seeley, William W; Malhotra, Dheeraj; Geschwind, Daniel H.

bioRxiv ; 2023 Sep 30.

Article in English | MEDLINE | ID: mdl-37808727

11.

Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations.

Liu, Dongjing; Meyer, Dara; Fennessy, Brian; Feng, Claudia; Cheng, Esther; Johnson, Jessica S; Park, You Jeong; Rieder, Marysia-Kolbe; Ascolillo, Steven; de Pins, Agathe; Dobbyn, Amanda; Lebovitch, Dannielle; Moya, Emily; Nguyen, Tan-Hoang; Wilkins, Lillian; Hassan, Arsalan; Burdick, Katherine E; Buxbaum, Joseph D; Domenici, Enrico; Frangou, Sophia; Hartmann, Annette M; Laurent-Levinson, Claudine; Malhotra, Dheeraj; Pato, Carlos N; Pato, Michele T; Ressler, Kerry; Roussos, Panos; Rujescu, Dan; Arango, Celso; Bertolino, Alessandro; Blasi, Giuseppe; Bocchio-Chiavetto, Luisella; Campion, Dominique; Carr, Vaughan; Fullerton, Janice M; Gennarelli, Massimo; González-Peñas, Javier; Levinson, Douglas F; Mowry, Bryan; Nimgaokar, Vishwajit L; Pergola, Giulio; Rampino, Antonio; Cervilla, Jorge A; Rivera, Margarita; Schwab, Sibylle G; Wildenauer, Dieter B; Daly, Mark; Neale, Benjamin; Singh, Tarjinder; O'Donovan, Michael C.

Nat Genet ; 55(3): 369-376, 2023 03.

Article in English | MEDLINE | ID: mdl-36914870

12.

Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disorders.

Zhou, Xianjin; Nie, Zhiguo; Roberts, Amanda; Zhang, Dongxian; Sebat, Jonathan; Malhotra, Dheeraj; Kelsoe, John R; Geyer, Mark A.

Hum Mol Genet ; 19(19): 3797-805, 2010 Oct 01.

Article in English | MEDLINE | ID: mdl-20634195

13.

Association of variants in BAT1-LTA-TNF-BTNL2 genes within 6p21.3 region show graded risk to leprosy in unrelated cohorts of Indian population.

Ali, Shafat; Chopra, Rupali; Aggarwal, Shweta; Srivastava, Amit Kumar; Kalaiarasan, Ponnusamy; Malhotra, Dheeraj; Gochhait, Sailesh; Garg, Vijay K; Bhattacharya, S N; Bamezai, Rameshwar N K.

Hum Genet ; 131(5): 703-16, 2012 May.

Article in English | MEDLINE | ID: mdl-22071774

14.

Leprosy and the adaptation of human toll-like receptor 1.

Wong, Sunny H; Gochhait, Sailesh; Malhotra, Dheeraj; Pettersson, Fredrik H; Teo, Yik Y; Khor, Chiea C; Rautanen, Anna; Chapman, Stephen J; Mills, Tara C; Srivastava, Amit; Rudko, Aleksey; Freidin, Maxim B; Puzyrev, Valery P; Ali, Shafat; Aggarwal, Shweta; Chopra, Rupali; Reddy, Belum S N; Garg, Vijay K; Roy, Suchismita; Meisner, Sarah; Hazra, Sunil K; Saha, Bibhuti; Floyd, Sian; Keating, Brendan J; Kim, Cecilia; Fairfax, Benjamin P; Knight, Julian C; Hill, Philip C; Adegbola, Richard A; Hakonarson, Hakon; Fine, Paul E M; Pitchappan, Ramasamy M; Bamezai, Rameshwar N K; Hill, Adrian V S; Vannberg, Fredrik O.

PLoS Pathog ; 6: e1000979, 2010 Jul 01.

Article in English | MEDLINE | ID: mdl-20617178

15.

Genetic variations and interactions in anti-inflammatory cytokine pathway genes in the outcome of leprosy: a study conducted on a MassARRAY platform.

Aggarwal, Shweta; Ali, Shafat; Chopra, Rupali; Srivastava, Amit; Kalaiarasan, Ponnusamy; Malhotra, Dheeraj; Gochhait, Sailesh; Garg, Vijay K; Bhattacharya, S N; Bamezai, Rameshwar N K.

J Infect Dis ; 204(8): 1264-73, 2011 Oct 15.

Article in English | MEDLINE | ID: mdl-21917900

16.

Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders.

Bryois, Julien; Calini, Daniela; Macnair, Will; Foo, Lynette; Urich, Eduard; Ortmann, Ward; Iglesias, Victor Alejandro; Selvaraj, Suresh; Nutma, Erik; Marzin, Manuel; Amor, Sandra; Williams, Anna; Castelo-Branco, Gonçalo; Menon, Vilas; De Jager, Philip; Malhotra, Dheeraj.

Nat Neurosci ; 25(8): 1104-1112, 2022 08.

Article in English | MEDLINE | ID: mdl-35915177

17.

Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility.

Meijer, Mandy; Agirre, Eneritz; Kabbe, Mukund; van Tuijn, Cassandra A; Heskol, Abeer; Zheng, Chao; Mendanha Falcão, Ana; Bartosovic, Marek; Kirby, Leslie; Calini, Daniela; Johnson, Michael R; Corces, M Ryan; Montine, Thomas J; Chen, Xingqi; Chang, Howard Y; Malhotra, Dheeraj; Castelo-Branco, Gonçalo.

Neuron ; 110(7): 1193-1210.e13, 2022 04 06.

Article in English | MEDLINE | ID: mdl-35093191

18.

CellMixS: quantifying and visualizing batch effects in single-cell RNA-seq data.

Lütge, Almut; Zyprych-Walczak, Joanna; Brykczynska Kunzmann, Urszula; Crowell, Helena L; Calini, Daniela; Malhotra, Dheeraj; Soneson, Charlotte; Robinson, Mark D.

Life Sci Alliance ; 4(6)2021 06.

Article in English | MEDLINE | ID: mdl-33758076

19.

muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data.

Crowell, Helena L; Soneson, Charlotte; Germain, Pierre-Luc; Calini, Daniela; Collin, Ludovic; Raposo, Catarina; Malhotra, Dheeraj; Robinson, Mark D.

Nat Commun ; 11(1): 6077, 2020 11 30.

Article in English | MEDLINE | ID: mdl-33257685

20.

Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression.

Rexach, Jessica E; Polioudakis, Damon; Yin, Anna; Swarup, Vivek; Chang, Timothy S; Nguyen, Tam; Sarkar, Arjun; Chen, Lawrence; Huang, Jerry; Lin, Li-Chun; Seeley, William; Trojanowski, John Q; Malhotra, Dheeraj; Geschwind, Daniel H.

Cell Rep ; 33(7): 108398, 2020 11 17.

Article in English | MEDLINE | ID: mdl-33207193

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Latin-American Center for Perinatology, Woman and Reproductive Health

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