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1.
Tinostamustine (EDO-S101), an Alkylating Deacetylase Inhibitor, Enhances the Efficacy of Daratumumab in Multiple Myeloma by Upregulation of CD38 and NKG2D Ligands.
Int J Mol Sci
; 25(9)2024 Apr 26.
Article
in English
| MEDLINE | ID: mdl-38731936
2.
Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.
Haematologica
; 102(1): 168-175, 2017 01.
Article
in English
| MEDLINE | ID: mdl-27540138
3.
The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Haematologica
; 102(12): 2113-2124, 2017 12.
Article
in English
| MEDLINE | ID: mdl-28860344
4.
Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma.
Haematologica
; 105(3): e116-e120, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31320555
5.
Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma.
Cells
; 10(3)2021 03 04.
Article
in English
| MEDLINE | ID: mdl-33806619
6.
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Nat Commun
; 12(1): 421, 2021 01 18.
Article
in English
| MEDLINE | ID: mdl-33462210
7.
Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma.
Cancers (Basel)
; 12(10)2020 Sep 24.
Article
in English
| MEDLINE | ID: mdl-32987735
8.
The Novel Pan-PIM Kinase Inhibitor, PIM447, Displays Dual Antimyeloma and Bone-Protective Effects, and Potently Synergizes with Current Standards of Care.
Clin Cancer Res
; 23(1): 225-238, 2017 Jan 01.
Article
in English
| MEDLINE | ID: mdl-27440267
9.
Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
J Hematol Oncol
; 10(1): 127, 2017 06 20.
Article
in English
| MEDLINE | ID: mdl-28633670
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