Search details
1.
A Global Map of G Protein Signaling Regulation by RGS Proteins.
Cell
; 183(2): 503-521.e19, 2020 10 15.
Article
in English
| MEDLINE | ID: mdl-33007266
2.
Pharmacogenomics of GPCR Drug Targets.
Cell
; 172(1-2): 41-54.e19, 2018 01 11.
Article
in English
| MEDLINE | ID: mdl-29249361
3.
GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.
Proc Natl Acad Sci U S A
; 117(25): 14522-14531, 2020 06 23.
Article
in English
| MEDLINE | ID: mdl-32513692
4.
Effects of Small Molecule Ligands on ACKR3 Receptors.
Mol Pharmacol
; 102(3): 128-138, 2022 09.
Article
in English
| MEDLINE | ID: mdl-35809897
5.
The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects.
J Biol Chem
; 295(31): 10822-10830, 2020 07 31.
Article
in English
| MEDLINE | ID: mdl-32576659
6.
PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
J Biol Chem
; 293(36): 13897-13909, 2018 09 07.
Article
in English
| MEDLINE | ID: mdl-29997255
7.
Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans.
Hum Mol Genet
; 26(6): 1078-1086, 2017 03 15.
Article
in English
| MEDLINE | ID: mdl-28087732
8.
LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
J Biol Chem
; 292(36): 14989-15001, 2017 09 08.
Article
in English
| MEDLINE | ID: mdl-28739799
9.
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.
J Biol Chem
; 290(22): 13622-39, 2015 May 29.
Article
in English
| MEDLINE | ID: mdl-25792749
10.
Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.
J Biol Chem
; 288(35): 25129-25142, 2013 Aug 30.
Article
in English
| MEDLINE | ID: mdl-23857581
11.
Rules and mechanisms governing G protein coupling selectivity of GPCRs.
Cell Rep
; 42(10): 113173, 2023 10 31.
Article
in English
| MEDLINE | ID: mdl-37742189
12.
Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors.
J Biol Chem
; 286(33): 28954-28962, 2011 Aug 19.
Article
in English
| MEDLINE | ID: mdl-21712387
13.
Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors.
J Biol Chem
; 286(24): 21806-13, 2011 Jun 17.
Article
in English
| MEDLINE | ID: mdl-21511947
14.
Ligand-directed bias of G protein signaling at the dopamine D2 receptor.
Cell Chem Biol
; 29(2): 226-238.e4, 2022 02 17.
Article
in English
| MEDLINE | ID: mdl-34302750
15.
Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons.
J Neurosci
; 30(41): 13784-93, 2010 Oct 13.
Article
in English
| MEDLINE | ID: mdl-20943919
16.
Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling.
J Biol Chem
; 285(7): 4781-7, 2010 Feb 12.
Article
in English
| MEDLINE | ID: mdl-20007977
17.
Diversity of the Gßγ complexes defines spatial and temporal bias of GPCR signaling.
Cell Syst
; 12(4): 324-337.e5, 2021 04 21.
Article
in English
| MEDLINE | ID: mdl-33667409
18.
Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders.
Cell Rep
; 34(5): 108718, 2021 02 02.
Article
in English
| MEDLINE | ID: mdl-33535037
19.
Extended Phenotyping and Functional Validation Facilitate Diagnosis of a Complex Patient Harboring Genetic Variants in MCCC1 and GNB5 Causing Overlapping Phenotypes.
Genes (Basel)
; 12(9)2021 08 29.
Article
in English
| MEDLINE | ID: mdl-34573334
20.
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.
J Neurosci
; 29(29): 9301-13, 2009 Jul 22.
Article
in English
| MEDLINE | ID: mdl-19625520