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1.
Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis.
Proteins
; 90(1): 282-298, 2022 01.
Article
in English
| MEDLINE | ID: mdl-34414607
2.
NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels.
Basic Res Cardiol
; 117(1): 24, 2022 04 25.
Article
in English
| MEDLINE | ID: mdl-35469044
3.
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
Proc Natl Acad Sci U S A
; 116(47): 23534-23541, 2019 11 19.
Article
in English
| MEDLINE | ID: mdl-31591207
4.
Inorganic arsenic promotes luminal to basal transition and metastasis of breast cancer.
FASEB J
; 34(12): 16034-16048, 2020 12.
Article
in English
| MEDLINE | ID: mdl-33047385
5.
The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).
J Biol Chem
; 292(2): 706-722, 2017 Jan 13.
Article
in English
| MEDLINE | ID: mdl-27909059
6.
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
Free Radic Biol Med
; 212: 493-504, 2024 02 20.
Article
in English
| MEDLINE | ID: mdl-38184120
7.
EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas.
bioRxiv
; 2024 Mar 16.
Article
in English
| MEDLINE | ID: mdl-38529489
8.
Changes in Daily Apparent Diffusion Coefficient on Fully Quantitative Magnetic Resonance Imaging Correlate With Established Genomic Pathways of Radiation Sensitivity and Reveal Novel Biologic Associations.
Int J Radiat Oncol Biol Phys
; 2024 May 29.
Article
in English
| MEDLINE | ID: mdl-38819340
9.
Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases.
J Biol Chem
; 287(16): 13026-39, 2012 Apr 13.
Article
in English
| MEDLINE | ID: mdl-22318730
10.
Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology.
J Biol Chem
; 287(10): 7010-25, 2012 Mar 02.
Article
in English
| MEDLINE | ID: mdl-22203677
11.
Pepsinogen/Proton Pump Co-Expression in Barrett's Esophageal Cells Induces Cancer-Associated Changes.
Laryngoscope
; 133(1): 59-69, 2023 01.
Article
in English
| MEDLINE | ID: mdl-35315085
12.
Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.
bioRxiv
; 2023 Apr 28.
Article
in English
| MEDLINE | ID: mdl-37207265
13.
Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction.
Front Genet
; 14: 1291307, 2023.
Article
in English
| MEDLINE | ID: mdl-38090150
14.
A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1.
bioRxiv
; 2023 Sep 07.
Article
in English
| MEDLINE | ID: mdl-37786696
15.
A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1.
Comput Struct Biotechnol J
; 21: 5249-5258, 2023.
Article
in English
| MEDLINE | ID: mdl-37954151
16.
The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Nat Commun
; 14(1): 1, 2023 01 03.
Article
in English
| MEDLINE | ID: mdl-36596776
17.
Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape.
Comput Struct Biotechnol J
; 21: 4790-4803, 2023.
Article
in English
| MEDLINE | ID: mdl-37841325
18.
Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs ß-Cell Function.
Function (Oxf)
; 3(4): zqac034, 2022.
Article
in English
| MEDLINE | ID: mdl-35873655
19.
Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.
Comput Struct Biotechnol J
; 20: 117-127, 2022.
Article
in English
| MEDLINE | ID: mdl-34976316
20.
Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons.
Genes (Basel)
; 13(2)2022 01 27.
Article
in English
| MEDLINE | ID: mdl-35205286