Search details
1.
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms.
Bioorg Med Chem Lett
; 24(8): 1968-73, 2014 Apr 15.
Article
in English
| MEDLINE | ID: mdl-24666646
2.
The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: lead optimization.
Bioorg Med Chem Lett
; 24(6): 1466-71, 2014 Mar 15.
Article
in English
| MEDLINE | ID: mdl-24582987
3.
MK-4827, a PARP-1/-2 inhibitor, strongly enhances response of human lung and breast cancer xenografts to radiation.
Invest New Drugs
; 30(6): 2113-20, 2012 Dec.
Article
in English
| MEDLINE | ID: mdl-22127459
4.
Reduced blockade by extracellular Mg(2+) is permissive to NMDA receptor activation in cerebellar granule neurons that model a migratory phenotype.
J Neurochem
; 114(1): 191-202, 2010 Jul.
Article
in English
| MEDLINE | ID: mdl-20403073
5.
The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: hit to lead.
Bioorg Med Chem Lett
; 20(24): 7421-5, 2010 Dec 15.
Article
in English
| MEDLINE | ID: mdl-21044843
6.
Development of a cell-based assay for measurement of c-Met phosphorylation using AlphaScreen technology and high-content imaging analysis.
J Biomol Screen
; 14(4): 404-11, 2009 Apr.
Article
in English
| MEDLINE | ID: mdl-19403923
7.
Roscovitine, olomoucine, purvalanol: inducers of apoptosis in maturing cerebellar granule neurons.
Biochem Pharmacol
; 67(10): 1947-64, 2004 May 15.
Article
in English
| MEDLINE | ID: mdl-15130771
8.
FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
PLoS One
; 9(6): e98515, 2014.
Article
in English
| MEDLINE | ID: mdl-24968263
9.
Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia vera.
PLoS One
; 7(5): e37207, 2012.
Article
in English
| MEDLINE | ID: mdl-22623993
10.
Splenectomy normalizes hematocrit in murine polycythemia vera.
PLoS One
; 4(9): e7286, 2009 Sep 30.
Article
in English
| MEDLINE | ID: mdl-19789710
11.
An inhibitor of Janus kinase 2 prevents polycythemia in mice.
Biochem Pharmacol
; 78(4): 382-9, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-19413997
12.
Trophic agents that prevent neuronal apoptosis activate calpain and down-regulate CaMKIV.
J Neurochem
; 81(2): 314-24, 2002 Apr.
Article
in English
| MEDLINE | ID: mdl-12064479
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