Search details
1.
Reversible cysteine protease inhibitors show promise for a Chagas disease cure.
Antimicrob Agents Chemother
; 58(2): 1167-78, 2014.
Article
in English
| MEDLINE | ID: mdl-24323474
2.
3,4-Diarylpiperidines as potent renin inhibitors.
Bioorg Med Chem Lett
; 22(5): 1953-7, 2012 Mar 01.
Article
in English
| MEDLINE | ID: mdl-22325946
3.
Probing cathepsin S activity in whole blood by the activity-based probe BIL-DMK: cellular distribution in human leukocyte populations and evidence of diurnal modulation.
Anal Biochem
; 411(1): 43-9, 2011 Apr 01.
Article
in English
| MEDLINE | ID: mdl-21094118
4.
Difluoroethylamines as an amide isostere in inhibitors of cathepsin K.
Bioorg Med Chem Lett
; 21(3): 920-3, 2011 Feb 01.
Article
in English
| MEDLINE | ID: mdl-21232956
5.
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Bioorg Med Chem Lett
; 21(1): 288-93, 2011 Jan 01.
Article
in English
| MEDLINE | ID: mdl-21106375
6.
Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease.
Bioorg Med Chem Lett
; 20(24): 7444-9, 2010 Dec 15.
Article
in English
| MEDLINE | ID: mdl-21041084
7.
The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor.
Bioorg Med Chem Lett
; 20(3): 887-92, 2010 Feb 01.
Article
in English
| MEDLINE | ID: mdl-20061146
8.
The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.
J Med Chem
; 53(5): 2227-38, 2010 Mar 11.
Article
in English
| MEDLINE | ID: mdl-20163116
9.
TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).
J Antibiot (Tokyo)
; 62(10): 565-70, 2009 Oct.
Article
in English
| MEDLINE | ID: mdl-19680283
10.
Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis.
J Med Chem
; 51(20): 6410-20, 2008 Oct 23.
Article
in English
| MEDLINE | ID: mdl-18811135
11.
Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones.
Bioorg Med Chem Lett
; 17(6): 1671-4, 2007 Mar 15.
Article
in English
| MEDLINE | ID: mdl-17251019
12.
Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors.
Bioorg Med Chem Lett
; 15(17): 3886-90, 2005 Sep 01.
Article
in English
| MEDLINE | ID: mdl-16023344
13.
Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitors.
Bioorg Med Chem Lett
; 14(16): 4291-5, 2004 Aug 16.
Article
in English
| MEDLINE | ID: mdl-15261289
14.
An activity-based probe for the determination of cysteine cathepsin protease activities in whole cells.
Anal Biochem
; 335(2): 218-27, 2004 Dec 15.
Article
in English
| MEDLINE | ID: mdl-15556560
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