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1.
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Nature
; 604(7907): 749-756, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35444283
2.
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.
Nature
; 511(7507): 90-3, 2014 Jul 03.
Article
in English
| MEDLINE | ID: mdl-24870236
3.
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
Mol Cell
; 30(6): 689-700, 2008 Jun 20.
Article
in English
| MEDLINE | ID: mdl-18570872
4.
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
J Med Chem
; 65(19): 13198-13215, 2022 10 13.
Article
in English
| MEDLINE | ID: mdl-36126059
5.
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Apoptosis
; 16(1): 67-74, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20938744
6.
Cytoprotective effects of IAPs revealed by a small molecule antagonist.
Biochem J
; 417(3): 765-71, 2009 Feb 01.
Article
in English
| MEDLINE | ID: mdl-18851715
7.
AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70.
Chem Biol
; 13(2): 213-23, 2006 Feb.
Article
in English
| MEDLINE | ID: mdl-16492569
8.
Differential desensitization of dopamine D2 receptor isoforms by protein kinase C: the importance of receptor phosphorylation and pseudosubstrate sites.
Eur J Pharmacol
; 577(1-3): 44-53, 2007 Dec 22.
Article
in English
| MEDLINE | ID: mdl-17869243
9.
Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis.
Clin Cancer Res
; 12(17): 5231-41, 2006 Sep 01.
Article
in English
| MEDLINE | ID: mdl-16951243
10.
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion.
J Neurosci
; 25(12): 3132-41, 2005 Mar 23.
Article
in English
| MEDLINE | ID: mdl-15788770
11.
Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics.
Oncogene
; 23(49): 8105-17, 2004 Oct 21.
Article
in English
| MEDLINE | ID: mdl-15378029
12.
Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide.
J Neurosci
; 23(25): 8788-99, 2003 Sep 24.
Article
in English
| MEDLINE | ID: mdl-14507979
13.
Disruption of a receptor-mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia.
Mol Endocrinol
; 17(9): 1856-67, 2003 Sep.
Article
in English
| MEDLINE | ID: mdl-12829804
14.
Fibula stress fracture and confounding myositis ossificans.
Clin Nucl Med
; 29(12): 813-4, 2004 Dec.
Article
in English
| MEDLINE | ID: mdl-15545889
15.
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
J Clin Oncol
; 27(28): 4741-6, 2009 Oct 01.
Article
in English
| MEDLINE | ID: mdl-19652057
16.
X-linked inhibitor of apoptosis regulates T cell effector function.
J Immunol
; 179(11): 7553-60, 2007 Dec 01.
Article
in English
| MEDLINE | ID: mdl-18025200
17.
Extremely low frequency electromagnetic field exposure promotes differentiation of pituitary corticotrope-derived AtT20 D16V cells.
Bioelectromagnetics
; 27(8): 641-51, 2006 Dec.
Article
in English
| MEDLINE | ID: mdl-16838272
18.
Electric-field assisted growth and self-assembly of intrinsic silicon nanowires.
Nano Lett
; 5(4): 705-8, 2005 Apr.
Article
in English
| MEDLINE | ID: mdl-15826112
19.
Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway.
J Biol Chem
; 278(48): 48129-36, 2003 Nov 28.
Article
in English
| MEDLINE | ID: mdl-12970359
20.
K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK.
J Biol Chem
; 277(51): 49473-80, 2002 Dec 20.
Article
in English
| MEDLINE | ID: mdl-12388555
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