Search | VHL CLAP/WR-PAHO/WHO

1.

Nucleolar RNA polymerase II drives ribosome biogenesis.

Abraham, Karan J; Khosraviani, Negin; Chan, Janet N Y; Gorthi, Aparna; Samman, Anas; Zhao, Dorothy Y; Wang, Miling; Bokros, Michael; Vidya, Elva; Ostrowski, Lauren A; Oshidari, Roxanne; Pietrobon, Violena; Patel, Parasvi S; Algouneh, Arash; Singhania, Rajat; Liu, Yupeng; Yerlici, V Talya; De Carvalho, Daniel D; Ohh, Michael; Dickson, Brendan C; Hakem, Razq; Greenblatt, Jack F; Lee, Stephen; Bishop, Alexander J R; Mekhail, Karim.

Nature ; 585(7824): 298-302, 2020 09.

Article in English | MEDLINE | ID: mdl-32669707

2.

Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.

Ting, Kenneth K Y; Yu, Pei; Dow, Riley; Floro, Eric; Ibrahim, Hisham; Scipione, Corey A; Hyduk, Sharon J; Polenz, Chanele K; Zaslaver, Olga; Karmaus, Peer W F; Fessler, Michael B; Röst, Hannes L; Ohh, Michael; Tsai, Sue; Winer, Daniel A; Woo, Minna; Rocheleau, Jonathan; Jongstra-Bilen, Jenny; Cybulsky, Myron I.

J Immunol ; 211(10): 1561-1577, 2023 11 15.

Article in English | MEDLINE | ID: mdl-37756544

3.

Side population analysis in clear cell renal cell carcinoma.

Huang, Richard; Meens, Jalna; Yuzwa, Scott; Ailles, Laurie; Ohh, Michael; Robinson, Claire M.

Biochem Biophys Res Commun ; 585: 196-202, 2021 12 31.

Article in English | MEDLINE | ID: mdl-34813980

4.

Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells.

Fernandez Esmerats, Joan; Villa-Roel, Nicolas; Kumar, Sandeep; Gu, Lina; Salim, Md Tausif; Ohh, Michael; Taylor, W Robert; Nerem, Robert M; Yoganathan, Ajit P; Jo, Hanjoong.

Arterioscler Thromb Vasc Biol ; 39(3): 467-481, 2019 03.

Article in English | MEDLINE | ID: mdl-30602302

5.

New structural and functional insight into the regulation of Ras.

Kano, Yoshihito; Cook, Jonathan D; Lee, Jeffrey E; Ohh, Michael.

Semin Cell Dev Biol ; 58: 70-8, 2016 10.

Article in English | MEDLINE | ID: mdl-27297135

6.

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.

Patel, Deven; Salloum, Darin; Saqcena, Mahesh; Chatterjee, Amrita; Mroz, Victoria; Ohh, Michael; Foster, David A.

J Biol Chem ; 292(3): 936-944, 2017 01 20.

Article in English | MEDLINE | ID: mdl-27956548

7.

Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling.

Heir, Pardeep; Srikumar, Tharan; Bikopoulos, George; Bunda, Severa; Poon, Betty P; Lee, Jeffrey E; Raught, Brian; Ohh, Michael.

J Biol Chem ; 291(14): 7357-72, 2016 Apr 01.

Article in English | MEDLINE | ID: mdl-26846855

8.

Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.

Bunda, Severa; Heir, Pardeep; Srikumar, Tharan; Cook, Jonathan D; Burrell, Kelly; Kano, Yoshihito; Lee, Jeffrey E; Zadeh, Gelareh; Raught, Brian; Ohh, Michael.

Proc Natl Acad Sci U S A ; 111(36): E3785-94, 2014 Sep 09.

Article in English | MEDLINE | ID: mdl-25157176

9.

The updated biology of hypoxia-inducible factor.

Greer, Samantha N; Metcalf, Julie L; Wang, Yi; Ohh, Michael.

EMBO J ; 31(11): 2448-60, 2012 May 30.

Article in English | MEDLINE | ID: mdl-22562152

10.

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1.

Wang, Yi; Roche, Olga; Xu, Chaoying; Moriyama, Eduardo H; Heir, Pardeep; Chung, Jacky; Roos, Frederik C; Chen, Yonghong; Finak, Greg; Milosevic, Michael; Wilson, Brian C; Teh, Bin Tean; Park, Morag; Irwin, Meredith S; Ohh, Michael.

Proc Natl Acad Sci U S A ; 109(13): 4892-7, 2012 Mar 27.

Article in English | MEDLINE | ID: mdl-22411794

11.

pVHL's kryptonite: E2-EPF UCP.

Ohh, Michael.

Cancer Cell ; 10(2): 95-7, 2006 Aug.

Article in English | MEDLINE | ID: mdl-16904608

12.

Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome.

Ferens, Fraser G; Taber, Cassandra C; Stuart, Sarah; Hubert, Mia; Tarade, Daniel; Lee, Jeffrey E; Ohh, Michael.

Commun Biol ; 7(1): 240, 2024 Feb 28.

Article in English | MEDLINE | ID: mdl-38418569

13.

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

Ho, J J David; Metcalf, Julie L; Yan, Matthew S; Turgeon, Paul J; Wang, Jenny Jing; Chalsev, Maria; Petruzziello-Pellegrini, Tania N; Tsui, Albert K Y; He, Jeff Z; Dhamko, Helena; Man, H S Jeffrey; Robb, G Brett; Teh, Bin T; Ohh, Michael; Marsden, Philip A.

J Biol Chem ; 287(34): 29003-20, 2012 Aug 17.

Article in English | MEDLINE | ID: mdl-22745131

14.

SHP2 Inhibition with TNO155 Increases Efficacy and Overcomes Resistance of ALK Inhibitors in Neuroblastoma.

Valencia-Sama, Ivette; Kee, Lynn; Christopher, Gabriella; Ohh, Michael; Layeghifard, Mehdi; Shlien, Adam; Hayes, Madeline N; Irwin, Meredith S.

Cancer Res Commun ; 3(12): 2608-2622, 2023 12 27.

Article in English | MEDLINE | ID: mdl-38032104

15.

Deregulation of E2-EPF ubiquitin carrier protein in papillary renal cell carcinoma.

Roos, Frederik C; Evans, Andrew J; Brenner, Walburgis; Wondergem, Bill; Klomp, Jeffery; Heir, Pardeep; Roche, Olga; Thomas, Christian; Schimmel, Heiko; Furge, Kyle A; Teh, Bin T; Thüroff, Joachim W; Hampel, Christian; Ohh, Michael.

Am J Pathol ; 178(2): 853-60, 2011 Feb.

Article in English | MEDLINE | ID: mdl-21281817

16.

SATB2 augments ΔNp63α in head and neck squamous cell carcinoma.

Chung, Jacky; Lau, Joanne; Cheng, Lynn S; Grant, R Ian; Robinson, Fiona; Ketela, Troy; Reis, Patricia P; Roche, Olga; Kamel-Reid, Suzanne; Moffat, Jason; Ohh, Michael; Perez-Ordonez, Bayardo; Kaplan, David R; Irwin, Meredith S.

EMBO Rep ; 11(10): 777-83, 2010 Oct.

Article in English | MEDLINE | ID: mdl-20829881

17.

Hypoxia-inducible factor underlies von Hippel-Lindau disease stigmata.

Ohh, Michael; Taber, Cassandra C; Ferens, Fraser G; Tarade, Daniel.

Elife ; 112022 08 30.

Article in English | MEDLINE | ID: mdl-36040300

18.

D154Q Mutation does not Alter KRAS Dimerization.

Grozavu, Ingrid; Stuart, Sarah; Lyakisheva, Anna; Yao, Zhong; Pathmanathan, Shivanthy; Ohh, Michael; Stagljar, Igor.

J Mol Biol ; 434(2): 167392, 2022 01 30.

Article in English | MEDLINE | ID: mdl-34896362

19.

Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response.

Koeman, Julie M; Russell, Ryan C; Tan, Min-Han; Petillo, David; Westphal, Michael; Koelzer, Katherine; Metcalf, Julie L; Zhang, Zhongfa; Matsuda, Daisuke; Dykema, Karl J; Houseman, Heather L; Kort, Eric J; Furge, Laura L; Kahnoski, Richard J; Richard, Stéphane; Vieillefond, Annick; Swiatek, Pamela J; Teh, Bin Tean; Ohh, Michael; Furge, Kyle A.

PLoS Genet ; 4(9): e1000176, 2008 Sep 05.

Article in English | MEDLINE | ID: mdl-18773095

20.

HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate.

He, Wenguang; Batty-Stuart, Sarah; Lee, Jeffrey E; Ohh, Michael.

J Mol Biol ; 433(22): 167244, 2021 11 05.

Article in English | MEDLINE | ID: mdl-34537235

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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