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1.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Nature
; 591(7850): 451-457, 2021 03.
Article
in English
| MEDLINE | ID: mdl-33561864
2.
Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine.
J Virol
; 98(4): e0013224, 2024 Apr 16.
Article
in English
| MEDLINE | ID: mdl-38511932
3.
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
PLoS Pathog
; 19(4): e1011342, 2023 04.
Article
in English
| MEDLINE | ID: mdl-37068076
4.
Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.
J Infect Dis
; 224(Supplement_1): S1-S21, 2021 Jul 15.
Article
in English
| MEDLINE | ID: mdl-34111271
5.
Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2.
Antimicrob Agents Chemother
; 65(5)2021 05 01.
Article
in English
| MEDLINE | ID: mdl-33649113
6.
Analysis of the Potential for N4-Hydroxycytidine To Inhibit Mitochondrial Replication and Function.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Article
in English
| MEDLINE | ID: mdl-31767721
7.
Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.
J Virol
; 93(24)2019 12 15.
Article
in English
| MEDLINE | ID: mdl-31578288
8.
ß-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome.
J Virol
; 92(3)2018 02 01.
Article
in English
| MEDLINE | ID: mdl-29167335
9.
Simple In Vitro Assay To Evaluate the Incorporation Efficiency of Ribonucleotide Analog 5'-Triphosphates into RNA by Human Mitochondrial DNA-Dependent RNA Polymerase.
Antimicrob Agents Chemother
; 62(2)2018 02.
Article
in English
| MEDLINE | ID: mdl-29180528
10.
Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.
Antimicrob Agents Chemother
; 62(8)2018 08.
Article
in English
| MEDLINE | ID: mdl-29891600
11.
Analysis of Ribonucleotide 5'-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays.
Antimicrob Agents Chemother
; 61(3)2017 03.
Article
in English
| MEDLINE | ID: mdl-27993851
12.
Discovery and Development of the Anti-Human Immunodeficiency Virus Drug, Emtricitabine (Emtriva, FTC).
Acc Chem Res
; 49(10): 2091-2098, 2016.
Article
in English
| MEDLINE | ID: mdl-27704821
13.
Letter to the Editor in Response to Zhou et al.
J Infect Dis
; 224(8): 1442-1443, 2021 10 28.
Article
in English
| MEDLINE | ID: mdl-34251432
14.
4'-Fluorouridine inhibits alphavirus replication and infection in vitro and in vivo.
mBio
; : e0042024, 2024 May 03.
Article
in English
| MEDLINE | ID: mdl-38700353
15.
The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N4-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection.
Antiviral Res
; 209: 105453, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36379378
16.
Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models.
Nat Commun
; 14(1): 4731, 2023 08 07.
Article
in English
| MEDLINE | ID: mdl-37550333
17.
Population pharmacokinetics of molnupiravir in adults with COVID-19: Lack of clinically important exposure variation across individuals.
CPT Pharmacometrics Syst Pharmacol
; 12(12): 1859-1871, 2023 Dec.
Article
in English
| MEDLINE | ID: mdl-37798914
18.
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.
Antimicrob Agents Chemother
; 56(5): 2726-34, 2012 May.
Article
in English
| MEDLINE | ID: mdl-22391537
19.
SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19.
bioRxiv
; 2022 Feb 07.
Article
in English
| MEDLINE | ID: mdl-35169793
20.
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Science
; 375(6577): 161-167, 2022 Jan 14.
Article
in English
| MEDLINE | ID: mdl-34855509