Search details
1.
Human topoisomerases and their roles in genome stability and organization.
Nat Rev Mol Cell Biol
; 23(6): 407-427, 2022 06.
Article
in English
| MEDLINE | ID: mdl-35228717
2.
Genome Organization Drives Chromosome Fragility.
Cell
; 170(3): 507-521.e18, 2017 Jul 27.
Article
in English
| MEDLINE | ID: mdl-28735753
3.
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.
Cell
; 165(2): 357-71, 2016 Apr 07.
Article
in English
| MEDLINE | ID: mdl-27058666
4.
An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia.
Genes Dev
; 35(3-4): 250-260, 2021 02 01.
Article
in English
| MEDLINE | ID: mdl-33446567
5.
Roles of eukaryotic topoisomerases in transcription, replication and genomic stability.
Nat Rev Mol Cell Biol
; 17(11): 703-721, 2016 11.
Article
in English
| MEDLINE | ID: mdl-27649880
6.
Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability.
Mol Cell
; 79(5): 836-845.e7, 2020 09 03.
Article
in English
| MEDLINE | ID: mdl-32649884
7.
Multiview confocal super-resolution microscopy.
Nature
; 600(7888): 279-284, 2021 12.
Article
in English
| MEDLINE | ID: mdl-34837071
8.
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Mol Cell
; 75(2): 252-266.e8, 2019 07 25.
Article
in English
| MEDLINE | ID: mdl-31202577
9.
Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro.
Development
; 150(20)2023 10 15.
Article
in English
| MEDLINE | ID: mdl-36897562
10.
SLFN11 Blocks Stressed Replication Forks Independently of ATR.
Mol Cell
; 69(3): 371-384.e6, 2018 02 01.
Article
in English
| MEDLINE | ID: mdl-29395061
11.
Identification and characterization of topoisomerase III beta poisons.
Proc Natl Acad Sci U S A
; 120(34): e2218483120, 2023 08 22.
Article
in English
| MEDLINE | ID: mdl-37579177
12.
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT.
Hum Mol Genet
; 32(15): 2422-2440, 2023 07 20.
Article
in English
| MEDLINE | ID: mdl-37129502
13.
Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets.
Mol Cell Proteomics
; 22(8): 100602, 2023 08.
Article
in English
| MEDLINE | ID: mdl-37343696
14.
Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level.
Nucleic Acids Res
; 51(18): e97, 2023 10 13.
Article
in English
| MEDLINE | ID: mdl-37670571
15.
Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts.
Nucleic Acids Res
; 51(20): 10846-10866, 2023 11 10.
Article
in English
| MEDLINE | ID: mdl-37850658
16.
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer.
Mol Carcinog
; 63(6): 1024-1037, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38411275
17.
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.
Proc Natl Acad Sci U S A
; 118(6)2021 02 09.
Article
in English
| MEDLINE | ID: mdl-33536335
18.
Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome.
J Biol Chem
; 298(10): 102420, 2022 10.
Article
in English
| MEDLINE | ID: mdl-36030054
19.
A Phase I Study of a Combination of Liposomal Irinotecan and Veliparib in Solid Tumors.
Oncologist
; 28(5): 460-e298, 2023 05 08.
Article
in English
| MEDLINE | ID: mdl-37010988
20.
HTLV-1 bZIP factor impairs DNA mismatch repair system.
Biochem Biophys Res Commun
; 657: 43-49, 2023 05 21.
Article
in English
| MEDLINE | ID: mdl-36972660