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1.
Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
Cell
; 173(4): 864-878.e29, 2018 05 03.
Article
in English
| MEDLINE | ID: mdl-29681454
2.
IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors.
Mol Cell
; 84(2): 202-220.e15, 2024 Jan 18.
Article
in English
| MEDLINE | ID: mdl-38103559
3.
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Cell
; 155(3): 552-66, 2013 Oct 24.
Article
in English
| MEDLINE | ID: mdl-24243015
4.
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells.
Proc Natl Acad Sci U S A
; 121(7): e2318024121, 2024 Feb 13.
Article
in English
| MEDLINE | ID: mdl-38330014
5.
Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii.
Proc Natl Acad Sci U S A
; 119(51): e2213116119, 2022 12 20.
Article
in English
| MEDLINE | ID: mdl-36512492
6.
ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.
Genes Dev
; 31(17): 1770-1783, 2017 09 01.
Article
in English
| MEDLINE | ID: mdl-28982760
7.
Identification of Glucose Transport Modulators In Vitro and Method for Their Deep Learning Neural Network Behavioral Evaluation in Glucose Transporter 1-Deficient Mice.
J Pharmacol Exp Ther
; 384(3): 393-405, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36635085
8.
Chemical screening identifies novel small molecule activators of natural killer cell cytotoxicity against cancer cells.
Cancer Immunol Immunother
; 71(7): 1671-1680, 2022 Jul.
Article
in English
| MEDLINE | ID: mdl-34816323
9.
Chemical intervention of influenza virus mRNA nuclear export.
PLoS Pathog
; 16(4): e1008407, 2020 04.
Article
in English
| MEDLINE | ID: mdl-32240278
10.
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Nature
; 538(7623): 114-117, 2016 Oct 06.
Article
in English
| MEDLINE | ID: mdl-27680702
11.
The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin α interactions.
Biochem J
; 477(17): 3253-3269, 2020 09 18.
Article
in English
| MEDLINE | ID: mdl-32776146
12.
Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors.
Molecules
; 26(19)2021 Sep 29.
Article
in English
| MEDLINE | ID: mdl-34641449
13.
Prostaglandin dehydrogenase is a target for successful induction of cervical ripening.
Proc Natl Acad Sci U S A
; 114(31): E6427-E6436, 2017 08 01.
Article
in English
| MEDLINE | ID: mdl-28716915
14.
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.
Nat Chem Biol
; 12(4): 218-25, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-26829472
15.
GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors.
Nat Chem Biol
; 11(1): 58-63, 2015 Jan.
Article
in English
| MEDLINE | ID: mdl-25402767
16.
Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives.
J Am Chem Soc
; 138(33): 10561-70, 2016 08 24.
Article
in English
| MEDLINE | ID: mdl-27459345
17.
Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening.
Bioorg Med Chem Lett
; 26(16): 3923-7, 2016 08 15.
Article
in English
| MEDLINE | ID: mdl-27426302
18.
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.
Proc Natl Acad Sci U S A
; 110(51): 20364-71, 2013 Dec 17.
Article
in English
| MEDLINE | ID: mdl-24277826
19.
Identification of DNMT1 selective antagonists using a novel scintillation proximity assay.
J Biol Chem
; 288(27): 19673-84, 2013 Jul 05.
Article
in English
| MEDLINE | ID: mdl-23671287
20.
Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp.
J Nat Prod
; 77(5): 1245-8, 2014 May 23.
Article
in English
| MEDLINE | ID: mdl-24754815