Search | VHL CLAP/WR-PAHO/WHO

1.

Utilizing graph machine learning within drug discovery and development.

Gaudelet, Thomas; Day, Ben; Jamasb, Arian R; Soman, Jyothish; Regep, Cristian; Liu, Gertrude; Hayter, Jeremy B R; Vickers, Richard; Roberts, Charles; Tang, Jian; Roblin, David; Blundell, Tom L; Bronstein, Michael M; Taylor-King, Jake P.

Brief Bioinform ; 22(6)2021 11 05.

Article in English | MEDLINE | ID: mdl-34013350

2.

Topical TrkA Kinase Inhibitor CT327 is an Effective, Novel Therapy for the Treatment of Pruritus due to Psoriasis: Results from Experimental Studies, and Efficacy and Safety of CT327 in a Phase 2b Clinical Trial in Patients with Psoriasis.

Roblin, David; Yosipovitch, Gil; Boyce, Brent; Robinson, John; Sandy, James; Mainero, Valentina; Wickramasinghe, Ro; Anand, Uma; Anand, Praveen.

Acta Derm Venereol ; 95(5): 542-8, 2015 May.

Article in English | MEDLINE | ID: mdl-25594427

3.

Pruritus severity in patients with psoriasis is not correlated with psoriasis disease severity.

Roblin, David; Wickramasinghe, Ro; Yosipovitch, Gil.

J Am Acad Dermatol ; 70(2): 390-1, 2014 Feb.

Article in English | MEDLINE | ID: mdl-24438964

4.

The Future of Machine Learning Within Target Identification: Causality, Reversibility, and Druggability.

Taylor-King, Jake P; Bronstein, Michael; Roblin, David.

Clin Pharmacol Ther ; 115(4): 655-657, 2024 04.

Article in English | MEDLINE | ID: mdl-38169071

5.

Combating resistance while maintaining innovation: the future of antimicrobial stewardship.

Vickers, Richard J; Bassetti, Matteo; Clancy, Cornelius J; Garey, Kevin W; Greenberg, David E; Nguyen, Minh-Hong; Roblin, David; Tillotson, Glenn S; Wilcox, Mark H.

Future Microbiol ; 14: 1331-1341, 2019 10.

Article in English | MEDLINE | ID: mdl-31526186

6.

Targeting Tropomyosin Receptor Kinase in Cutaneous CYLD Defective Tumors With Pegcantratinib: The TRAC Randomized Clinical Trial.

Danilenko, Marina; Stamp, Elaine; Stocken, Deborah D; Husain, Akhtar; Zangarini, Monique; Cranston, Amy; Stones, Robert; Sinclair, Naomi; Hodgson, Kirsty; Bowett, Susan A; Roblin, David; Traversa, Silvio; Plummer, Ruth; Veal, Gareth; Langtry, James A A; Ashworth, Alan; Burn, John; Rajan, Neil.

JAMA Dermatol ; 154(8): 913-921, 2018 08 01.

Article in English | MEDLINE | ID: mdl-29955768

7.

Translational research in the pharmaceutical industry: from theory to reality.

Sultana, Stefan R; Roblin, David; O'Connell, Damian.

Drug Discov Today ; 12(9-10): 419-25, 2007 May.

Article in English | MEDLINE | ID: mdl-17467579

8.

Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours: study protocol for a randomised controlled trial.

Cranston, Amy; Stocken, Deborah D; Stamp, Elaine; Roblin, David; Hamlin, Julia; Langtry, James; Plummer, Ruth; Ashworth, Alan; Burn, John; Rajan, Neil.

Trials ; 18(1): 111, 2017 03 07.

Article in English | MEDLINE | ID: mdl-28270164

9.

Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study.

Vickers, Richard J; Tillotson, Glenn S; Nathan, Richard; Hazan, Sabine; Pullman, John; Lucasti, Christopher; Deck, Kenneth; Yacyshyn, Bruce; Maliakkal, Benedict; Pesant, Yves; Tejura, Bina; Roblin, David; Gerding, Dale N; Wilcox, Mark H.

Lancet Infect Dis ; 17(7): 735-744, 2017 07.

Article in English | MEDLINE | ID: mdl-28461207

10.

Translational research in the pharmaceutical industry: from bench to bedside.

O'Connell, Damian; Roblin, David.

Drug Discov Today ; 11(17-18): 833-8, 2006 Sep.

Article in English | MEDLINE | ID: mdl-16935752

11.

Coronary and systemic hemodynamic effects of sildenafil citrate: from basic science to clinical studies in patients with cardiovascular disease.

Gillies, Hunter C; Roblin, David; Jackson, Graham.

Int J Cardiol ; 86(2-3): 131-41, 2002 Dec.

Article in English | MEDLINE | ID: mdl-12419549

12.

Seeking validation.

Roblin, David.

Sci Transl Med ; 4(136): 136ed5, 2012 May 30.

Article in English | MEDLINE | ID: mdl-22649087

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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