Search details
1.
Treatments Targeting the Androgen Receptor and Its Splice Variants in Breast Cancer.
Int J Mol Sci
; 25(3)2024 Feb 02.
Article
in English
| MEDLINE | ID: mdl-38339092
2.
Drugging the Undruggable: Targeting the N-Terminal Domain of Nuclear Hormone Receptors.
Adv Exp Med Biol
; 1390: 311-326, 2022.
Article
in English
| MEDLINE | ID: mdl-36107327
3.
Structure-Activity Relationships for the Marine Natural Product Sintokamides: Androgen Receptor N-Terminus Antagonists of Interest for Treatment of Metastatic Castration-Resistant Prostate Cancer.
J Nat Prod
; 84(3): 797-813, 2021 03 26.
Article
in English
| MEDLINE | ID: mdl-33124806
4.
Keys to unlock androgen receptor translocation.
J Biol Chem
; 294(22): 8711-8712, 2019 05 31.
Article
in English
| MEDLINE | ID: mdl-31152093
5.
Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.
J Biol Chem
; 291(42): 22231-22243, 2016 Oct 14.
Article
in English
| MEDLINE | ID: mdl-27576691
6.
Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer.
Oncologist
; 21(12): 1427-1435, 2016 12.
Article
in English
| MEDLINE | ID: mdl-27628492
7.
Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic.
Int J Urol
; 23(8): 654-65, 2016 08.
Article
in English
| MEDLINE | ID: mdl-27302572
8.
Piperazate-Guided Isolation of Caveamides A and B, Cyclohexenylalanine-Containing Nonribosomal Peptides from a Cave Actinomycete.
Org Lett
; 26(19): 4127-4131, 2024 May 17.
Article
in English
| MEDLINE | ID: mdl-38718303
9.
Rational optimization of a transcription factor activation domain inhibitor.
Nat Struct Mol Biol
; 30(12): 1958-1969, 2023 Dec.
Article
in English
| MEDLINE | ID: mdl-38049566
10.
Advances in small molecule inhibitors of androgen receptor for the treatment of advanced prostate cancer.
World J Urol
; 30(3): 311-8, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-21833557
11.
Androgen receptor and its splice variants in prostate cancer.
Cell Mol Life Sci
; 68(24): 3971-81, 2011 Dec.
Article
in English
| MEDLINE | ID: mdl-21748469
12.
Cyclin-dependent Kinase 4/6 Inhibitor Palbociclib in Combination with Ralaniten Analogs for the Treatment of Androgen Receptor-positive Prostate and Breast Cancers.
Mol Cancer Ther
; 21(2): 294-309, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34815359
13.
Differential Gene Expression Profiles between N-Terminal Domain and Ligand-Binding Domain Inhibitors of Androgen Receptor Reveal Ralaniten Induction of Metallothionein by a Mechanism Dependent on MTF1.
Cancers (Basel)
; 14(2)2022 Jan 13.
Article
in English
| MEDLINE | ID: mdl-35053548
14.
Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones.
Hum Cell
; 34(1): 211-218, 2021 Jan.
Article
in English
| MEDLINE | ID: mdl-32954481
15.
Pin1 inhibition improves the efficacy of ralaniten compounds that bind to the N-terminal domain of androgen receptor.
Commun Biol
; 4(1): 381, 2021 03 22.
Article
in English
| MEDLINE | ID: mdl-33753863
16.
Development of metastatic and non-metastatic tumor lines from a patient's prostate cancer specimen-identification of a small subpopulation with metastatic potential in the primary tumor.
Prostate
; 70(15): 1636-44, 2010 Nov 01.
Article
in English
| MEDLINE | ID: mdl-20564316
17.
Novel biomarkers for prostate cancer including noncoding transcripts.
Am J Pathol
; 175(6): 2264-76, 2009 Dec.
Article
in English
| MEDLINE | ID: mdl-19893039
18.
Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor.
Expert Opin Drug Discov
; 15(5): 551-560, 2020 05.
Article
in English
| MEDLINE | ID: mdl-32100577
19.
Combination therapy with androgen receptor N-terminal domain antagonist EPI-7170 and enzalutamide yields synergistic activity in AR-V7-positive prostate cancer.
Mol Oncol
; 14(10): 2455-2470, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32734688
20.
Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants.
Cancers (Basel)
; 12(7)2020 Jul 21.
Article
in English
| MEDLINE | ID: mdl-32708219