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1.
High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry.
Anal Chem
; 95(47): 17263-17272, 2023 11 28.
Article
in English
| MEDLINE | ID: mdl-37956201
2.
High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry.
Proc Natl Acad Sci U S A
; 117(18): 9851-9856, 2020 05 05.
Article
in English
| MEDLINE | ID: mdl-32327606
3.
Using a peptide-based mass spectrometry approach to quantitate proteolysis of an intact heterogeneous procollagen substrate by BMP1 for antagonistic antibody screening.
Anal Bioanal Chem
; 414(22): 6601-6610, 2022 Sep.
Article
in English
| MEDLINE | ID: mdl-35821276
4.
Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes.
J Lipid Res
; 61(6): 870-883, 2020 06.
Article
in English
| MEDLINE | ID: mdl-32156718
5.
Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
J Am Chem Soc
; 142(9): 4445-4455, 2020 03 04.
Article
in English
| MEDLINE | ID: mdl-32064871
6.
Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism.
Proc Natl Acad Sci U S A
; 113(41): E6064-E6071, 2016 10 11.
Article
in English
| MEDLINE | ID: mdl-27681620
7.
Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system.
Protein Expr Purif
; 117: 44-51, 2016 Jan.
Article
in English
| MEDLINE | ID: mdl-26405011
8.
Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.
J Bacteriol
; 198(4): 731-41, 2015 Dec 14.
Article
in English
| MEDLINE | ID: mdl-26668262
9.
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.
J Med Chem
; 64(5): 2576-2607, 2021 03 11.
Article
in English
| MEDLINE | ID: mdl-33596073
10.
Improved translation of stability for conjugated antibodies using an in vitro whole blood assay.
MAbs
; 12(1): 1715705, 2020.
Article
in English
| MEDLINE | ID: mdl-31997712
11.
Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
J Med Chem
; 63(14): 7773-7816, 2020 07 23.
Article
in English
| MEDLINE | ID: mdl-32634310
12.
Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry.
PLoS One
; 14(2): e0211803, 2019.
Article
in English
| MEDLINE | ID: mdl-30735516
13.
Molecular Probes for the Determination of Subcellular Compound Exposure Profiles in Gram-Negative Bacteria.
ACS Infect Dis
; 4(9): 1355-1367, 2018 09 14.
Article
in English
| MEDLINE | ID: mdl-29846057
14.
Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis.
mSphere
; 3(5)2018 10 31.
Article
in English
| MEDLINE | ID: mdl-30381354
15.
LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates.
mSphere
; 2(4)2017.
Article
in English
| MEDLINE | ID: mdl-28815210
16.
Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606.
PLoS One
; 11(8): e0160918, 2016.
Article
in English
| MEDLINE | ID: mdl-27526195
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