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1.
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2.
Proc Natl Acad Sci U S A
; 121(6): e2317756121, 2024 Feb 06.
Article
in English
| MEDLINE | ID: mdl-38300868
2.
Synthesis of antioxidants for prevention of age-related macular degeneration.
J Nat Prod
; 76(3): 450-4, 2013 Mar 22.
Article
in English
| MEDLINE | ID: mdl-23346866
3.
Profound methyl effects in drug discovery and a call for new C-H methylation reactions.
Angew Chem Int Ed Engl
; 52(47): 12256-67, 2013 Nov 18.
Article
in English
| MEDLINE | ID: mdl-24151256
4.
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Cancer Discov
; 13(9): 2012-2031, 2023 09 06.
Article
in English
| MEDLINE | ID: mdl-37270847
5.
An improved model for fragment-based lead generation at AstraZeneca.
Drug Discov Today
; 21(8): 1272-83, 2016 08.
Article
in English
| MEDLINE | ID: mdl-27179986
6.
Direct and highly enantioselective iso-Pictet-Spengler reactions with α-ketoamides: access to underexplored indole core structures.
Org Lett
; 14(10): 2610-3, 2012 May 18.
Article
in English
| MEDLINE | ID: mdl-22540677
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