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1.
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action.
J Biol Chem
; 299(1): 102729, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36410439
2.
Primary results and characterization of patients with exceptional outcomes in a phase 1b study combining PARP and MEK inhibition, with or without anti-PD-L1, for BRCA wild-type, platinum-sensitive, recurrent ovarian cancer.
Cancer
; 130(11): 1940-1951, 2024 Jun 01.
Article
in English
| MEDLINE | ID: mdl-38288862
3.
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.
Bioorg Med Chem Lett
; 26(2): 534-539, 2016 Jan 15.
Article
in English
| MEDLINE | ID: mdl-26639762
4.
LUZ-Y, a novel platform for the mammalian cell production of full-length IgG-bispecific antibodies.
J Biol Chem
; 287(52): 43331-9, 2012 Dec 21.
Article
in English
| MEDLINE | ID: mdl-23118228
5.
Engineering upper hinge improves stability and effector function of a human IgG1.
J Biol Chem
; 287(8): 5891-7, 2012 Feb 17.
Article
in English
| MEDLINE | ID: mdl-22203673
6.
Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry.
J Virol
; 86(20): 10935-49, 2012 Oct.
Article
in English
| MEDLINE | ID: mdl-22855500
7.
Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression.
Cancer Res
; 67(3): 1228-38, 2007 Feb 01.
Article
in English
| MEDLINE | ID: mdl-17283159
8.
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma.
Elife
; 82019 05 30.
Article
in English
| MEDLINE | ID: mdl-31144617
9.
ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer.
Cancer Res
; 79(19): 4828-4839, 2019 Oct 01.
Article
in English
| MEDLINE | ID: mdl-31416841
10.
Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.
PLoS One
; 13(1): e0192059, 2018.
Article
in English
| MEDLINE | ID: mdl-29370292
11.
"Two-in-One" approach for bioassay selection for dual specificity antibodies.
J Immunol Methods
; 448: 74-79, 2017 09.
Article
in English
| MEDLINE | ID: mdl-28579366
12.
Clinical responses to ERK inhibition in BRAFV600E-mutant colorectal cancer predicted using a computational model.
NPJ Syst Biol Appl
; 3: 14, 2017.
Article
in English
| MEDLINE | ID: mdl-28649441
13.
Erratum: Clinical responses to ERK inhibition in BRAFV600E-mutant colorectal cancer predicted using a computational model.
NPJ Syst Biol Appl
; 3: 25, 2017.
Article
in English
| MEDLINE | ID: mdl-28879057
14.
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.
PLoS One
; 12(10): e0185862, 2017.
Article
in English
| MEDLINE | ID: mdl-28982154
15.
High cell-surface density of HER2 deforms cell membranes.
Nat Commun
; 7: 12742, 2016 09 07.
Article
in English
| MEDLINE | ID: mdl-27599456
16.
Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR.
ACS Med Chem Lett
; 7(1): 100-4, 2016 Jan 14.
Article
in English
| MEDLINE | ID: mdl-26819674
17.
Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2.
Cancer Cell
; 29(4): 477-493, 2016 Apr 11.
Article
in English
| MEDLINE | ID: mdl-26996308
18.
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor.
J Med Chem
; 59(19): 9080-9093, 2016 10 13.
Article
in English
| MEDLINE | ID: mdl-27564586
19.
Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.
J Med Chem
; 58(22): 8877-95, 2015 Nov 25.
Article
in English
| MEDLINE | ID: mdl-26455919
20.
Dual targeting of HER2-positive cancer with trastuzumab emtansine and pertuzumab: critical role for neuregulin blockade in antitumor response to combination therapy.
Clin Cancer Res
; 20(2): 456-68, 2014 Jan 15.
Article
in English
| MEDLINE | ID: mdl-24097864