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1.
In vivo biodistribution and pharmacokinetics of sotrovimab, a SARS-CoV-2 monoclonal antibody, in healthy cynomolgus monkeys.
Eur J Nucl Med Mol Imaging
; 50(3): 667-678, 2023 02.
Article
in English
| MEDLINE | ID: mdl-36305907
2.
Application of physiologically based pharmacokinetic models for therapeutic proteins and other novel modalities.
Xenobiotica
; 52(8): 840-854, 2022 Aug.
Article
in English
| MEDLINE | ID: mdl-36214113
3.
Physiologically-based pharmacokinetic model for pulmonary disposition of protein therapeutics in humans.
J Pharmacokinet Pharmacodyn
; 49(6): 607-624, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36266517
4.
Computer-assembled cross-species/cross-modalities two-pore physiologically based pharmacokinetic model for biologics in mice and rats.
J Pharmacokinet Pharmacodyn
; 46(4): 339-359, 2019 08.
Article
in English
| MEDLINE | ID: mdl-31079322
5.
Development of a physiologically based pharmacokinetic model for a domain antibody in mice using the two-pore theory.
J Pharmacokinet Pharmacodyn
; 42(2): 97-109, 2015 Apr.
Article
in English
| MEDLINE | ID: mdl-25577033
6.
Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies.
MAbs
; 16(1): 2324485, 2024.
Article
in English
| MEDLINE | ID: mdl-38700511
7.
Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.
Eur J Pharm Sci
; 182: 106375, 2023 Mar 01.
Article
in English
| MEDLINE | ID: mdl-36626943
8.
Application of quantitative protein mass spectrometric data in the early predictive analysis of target engagement by monoclonal antibodies.
Clin Transl Sci
; 15(7): 1634-1643, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35445800
9.
Novel Selection Approaches to Identify Antibodies Targeting Neoepitopes on the C5b6 Intermediate Complex to Inhibit Membrane Attack Complex Formation.
Antibodies (Basel)
; 10(4)2021 Oct 12.
Article
in English
| MEDLINE | ID: mdl-34698051
10.
Cross-species/cross-modality physiologically based pharmacokinetics for biologics: 89Zr-labelled albumin-binding domain antibody GSK3128349 in humans.
MAbs
; 12(1): 1832861, 2020.
Article
in English
| MEDLINE | ID: mdl-33073698
11.
The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans.
EJNMMI Res
; 9(1): 45, 2019 May 21.
Article
in English
| MEDLINE | ID: mdl-31115711
12.
Cell-free selection of zinc finger DNA-binding proteins using in vitro compartmentalization.
J Mol Biol
; 354(2): 212-9, 2005 Nov 25.
Article
in English
| MEDLINE | ID: mdl-16242713
13.
Modeling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion.
MAbs
; 8(5): 905-15, 2016 07.
Article
in English
| MEDLINE | ID: mdl-27097222
14.
Pharmacokinetic characteristics, pharmacodynamic effect and in vivo antiviral efficacy of liver-targeted interferon alpha.
PLoS One
; 10(2): e0117847, 2015.
Article
in English
| MEDLINE | ID: mdl-25689509
15.
Microbead display by in vitro compartmentalisation: selection for binding using flow cytometry.
FEBS Lett
; 532(3): 455-8, 2002 Dec 18.
Article
in English
| MEDLINE | ID: mdl-12482612
16.
Liver-targeting of interferon-alpha with tissue-specific domain antibodies.
PLoS One
; 8(2): e57263, 2013.
Article
in English
| MEDLINE | ID: mdl-23451195
17.
Cell-free selection of domain antibodies by in vitro compartmentalization.
Methods Mol Biol
; 911: 183-98, 2012.
Article
in English
| MEDLINE | ID: mdl-22886253
18.
Next generation immunotherapeutics--honing the magic bullet.
Curr Opin Biotechnol
; 20(4): 405-11, 2009 Aug.
Article
in English
| MEDLINE | ID: mdl-19709876
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