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1.
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex.
Cell
; 146(1): 134-47, 2011 Jul 08.
Article
in English
| MEDLINE | ID: mdl-21729785
2.
Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events.
Mol Cell
; 58(2): 269-83, 2015 Apr 16.
Article
in English
| MEDLINE | ID: mdl-25801167
3.
Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1.
Mol Cell
; 41(6): 682-92, 2011 Mar 18.
Article
in English
| MEDLINE | ID: mdl-21419343
4.
The Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding.
J Biol Chem
; 290(48): 28944-52, 2015 Nov 27.
Article
in English
| MEDLINE | ID: mdl-26254469
5.
Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase.
J Biol Chem
; 288(43): 31069-79, 2013 Oct 25.
Article
in English
| MEDLINE | ID: mdl-23990462
6.
In vitro modulator responsiveness of 655 CFTR variants found in people with cystic fibrosis.
J Cyst Fibros
; 2024 Feb 21.
Article
in English
| MEDLINE | ID: mdl-38388235
7.
Kinetic analysis of ribosome-bound fluorescent proteins reveals an early, stable, cotranslational folding intermediate.
J Biol Chem
; 287(4): 2568-78, 2012 Jan 20.
Article
in English
| MEDLINE | ID: mdl-22128180
8.
Thermal instability of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: protection by single suppressor mutations and inhibiting channel activity.
Biochemistry
; 51(25): 5113-24, 2012 Jun 26.
Article
in English
| MEDLINE | ID: mdl-22680785
9.
Epstein-Barr viral BNLF2a protein hijacks the tail-anchored protein insertion machinery to block antigen processing by the transport complex TAP.
J Biol Chem
; 286(48): 41402-41412, 2011 Dec 02.
Article
in English
| MEDLINE | ID: mdl-21984826
10.
In vitro incorporation of nonnatural amino acids into protein using tRNA(Cys)-derived opal, ochre, and amber suppressor tRNAs.
RNA
; 16(8): 1660-72, 2010 Aug.
Article
in English
| MEDLINE | ID: mdl-20581130
11.
The cytoplasmic domain of rhesus cytomegalovirus Rh178 interrupts translation of major histocompatibility class I leader peptide-containing proteins prior to translocation.
J Virol
; 85(17): 8766-76, 2011 Sep.
Article
in English
| MEDLINE | ID: mdl-21715474
12.
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.
Nat Chem Biol
; 6(1): 25-33, 2010 Jan.
Article
in English
| MEDLINE | ID: mdl-19966789
13.
A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization.
Nat Struct Mol Biol
; 14(8): 762-9, 2007 Aug.
Article
in English
| MEDLINE | ID: mdl-17632520
14.
A small molecule high throughput screening platform to profile conformational properties of nascent, ribosome-bound proteins.
Sci Rep
; 12(1): 2509, 2022 02 15.
Article
in English
| MEDLINE | ID: mdl-35169219
15.
Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein.
Nat Struct Mol Biol
; 12(10): 870-8, 2005 Oct.
Article
in English
| MEDLINE | ID: mdl-16186821
16.
CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates.
Nat Commun
; 11(1): 4258, 2020 08 26.
Article
in English
| MEDLINE | ID: mdl-32848127
17.
Towards next generation therapies for cystic fibrosis: Folding, function and pharmacology of CFTR.
J Cyst Fibros
; 19 Suppl 1: S25-S32, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31902693
18.
Global organization and function of mammalian cytosolic proteasome pools: Implications for PA28 and 19S regulatory complexes.
Mol Biol Cell
; 17(12): 4962-71, 2006 Dec.
Article
in English
| MEDLINE | ID: mdl-16987959
19.
Engineered transfer RNAs for suppression of premature termination codons.
Nat Commun
; 10(1): 822, 2019 02 18.
Article
in English
| MEDLINE | ID: mdl-30778053
20.
Pharmacological chaperoning: two 'hits' are better than one.
Biochem J
; 406(2): e1-2, 2007 Sep 01.
Article
in English
| MEDLINE | ID: mdl-17680777