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1.
α-L-iduronidase fused with humanized anti-human transferrin receptor antibody (lepunafusp alfa) for mucopolysaccharidosis type I: A phase 1/2 trial.
Mol Ther
; 32(3): 609-618, 2024 Mar 06.
Article
in English
| MEDLINE | ID: mdl-38204164
2.
Iduronate-2-sulfatase fused with anti-hTfR antibody, pabinafusp alfa, for MPS-II: A phase 2 trial in Brazil.
Mol Ther
; 29(7): 2378-2386, 2021 07 07.
Article
in English
| MEDLINE | ID: mdl-33781915
3.
A Phase 2/3 Trial of Pabinafusp Alfa, IDS Fused with Anti-Human Transferrin Receptor Antibody, Targeting Neurodegeneration in MPS-II.
Mol Ther
; 29(2): 671-679, 2021 02 03.
Article
in English
| MEDLINE | ID: mdl-33038326
4.
Enzyme Replacement Therapy with Pabinafusp Alfa for Neuronopathic Mucopolysaccharidosis II: An Integrated Analysis of Preclinical and Clinical Data.
Int J Mol Sci
; 22(20)2021 Oct 10.
Article
in English
| MEDLINE | ID: mdl-34681597
5.
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.
Mol Cell
; 41(5): 529-42, 2011 Mar 04.
Article
in English
| MEDLINE | ID: mdl-21362549
6.
BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle.
Nucleic Acids Res
; 42(18): 11487-501, 2014 Oct.
Article
in English
| MEDLINE | ID: mdl-25223785
7.
Analysis of caregiver perspectives on patients with mucopolysaccharidosis II treated with pabinafusp alfa: results of qualitative interviews in Japan.
Orphanet J Rare Dis
; 19(1): 104, 2024 Mar 07.
Article
in English
| MEDLINE | ID: mdl-38454486
8.
hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex.
Nucleic Acids Res
; 39(5): 1692-702, 2011 Mar.
Article
in English
| MEDLINE | ID: mdl-21051358
9.
Treatment of Neuronopathic Mucopolysaccharidoses with Blood-Brain Barrier-Crossing Enzymes: Clinical Application of Receptor-Mediated Transcytosis.
Pharmaceutics
; 14(6)2022 Jun 11.
Article
in English
| MEDLINE | ID: mdl-35745811
10.
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.
J Biol Chem
; 285(2): 1414-23, 2010 Jan 08.
Article
in English
| MEDLINE | ID: mdl-19893054
11.
Divergent developmental trajectories in two siblings with neuropathic mucopolysaccharidosis type II (Hunter syndrome) receiving conventional and novel enzyme replacement therapies: A case report.
JIMD Rep
; 62(1): 9-14, 2021 Nov.
Article
in English
| MEDLINE | ID: mdl-34765392
12.
Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting.
Nucleic Acids Res
; 36(19): 6333-42, 2008 Nov.
Article
in English
| MEDLINE | ID: mdl-18835848
13.
Heterozygous inactivation of human Ku70/Ku86 heterodimer does not affect cell growth, double-strand break repair, or genome integrity.
DNA Repair (Amst)
; 5(3): 303-11, 2006 Mar 07.
Article
in English
| MEDLINE | ID: mdl-16325483
14.
Absence of p53 enhances growth defects and etoposide sensitivity of human cells lacking the Bloom syndrome helicase BLM.
DNA Cell Biol
; 26(7): 517-25, 2007 Jul.
Article
in English
| MEDLINE | ID: mdl-17630856
15.
Simple one-week method to construct gene-targeting vectors: application to production of human knockout cell lines.
Biotechniques
; 41(3): 311-6, 2006 Sep.
Article
in English
| MEDLINE | ID: mdl-16989091
16.
The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination.
DNA Cell Biol
; 25(1): 19-24, 2006 Jan.
Article
in English
| MEDLINE | ID: mdl-16405397
17.
DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair.
PLoS One
; 8(8): e72253, 2013.
Article
in English
| MEDLINE | ID: mdl-23967291
18.
Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination.
DNA Repair (Amst)
; 11(3): 310-6, 2012 Mar 01.
Article
in English
| MEDLINE | ID: mdl-22265216
19.
Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability.
Radiat Res
; 175(1): 83-9, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-21175350
20.
Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.
Cell Cycle
; 9(13): 2529-36, 2010 Jul 01.
Article
in English
| MEDLINE | ID: mdl-20543558