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1.
Correction: A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites.
PLoS Pathog
; 20(2): e1011987, 2024 Feb.
Article
in English
| MEDLINE | ID: mdl-38300903
2.
A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites.
PLoS Pathog
; 19(7): e1011517, 2023 07.
Article
in English
| MEDLINE | ID: mdl-37471441
3.
A novel heteromeric pantothenate kinase complex in apicomplexan parasites.
PLoS Pathog
; 17(7): e1009797, 2021 07.
Article
in English
| MEDLINE | ID: mdl-34324601
4.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
Angew Chem Int Ed Engl
; 62(17): e202300221, 2023 04 17.
Article
in English
| MEDLINE | ID: mdl-36757665
5.
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
PLoS Pathog
; 14(4): e1006918, 2018 04.
Article
in English
| MEDLINE | ID: mdl-29614109
6.
Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility-mass spectrometry.
Biochem J
; 476(21): 3125-3139, 2019 11 15.
Article
in English
| MEDLINE | ID: mdl-31488574
7.
Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.
Biochem Soc Trans
; 42(4): 1087-93, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-25110007
8.
A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices.
Anal Biochem
; 451: 76-8, 2014 Apr 15.
Article
in English
| MEDLINE | ID: mdl-24333332
9.
Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides.
Int J Parasitol Drugs Drug Resist
; 25: 100536, 2024 Apr 03.
Article
in English
| MEDLINE | ID: mdl-38663046
10.
Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target.
Int J Parasitol Drugs Drug Resist
; 22: 1-8, 2023 08.
Article
in English
| MEDLINE | ID: mdl-37004488
11.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
Angew Chem Weinheim Bergstr Ger
; 135(17): e202300221, 2023 Apr 17.
Article
in English
| MEDLINE | ID: mdl-38515507
12.
Exploring Heteroaromatic Rings as a Replacement for the Labile Amide of Antiplasmodial Pantothenamides.
J Med Chem
; 64(8): 4478-4497, 2021 04 22.
Article
in English
| MEDLINE | ID: mdl-33792339
13.
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
ACS Infect Dis
; 7(6): 1666-1679, 2021 06 11.
Article
in English
| MEDLINE | ID: mdl-33939919
14.
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Nat Commun
; 12(1): 143, 2021 01 08.
Article
in English
| MEDLINE | ID: mdl-33420031
15.
The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.
J Biol Chem
; 284(37): 24904-13, 2009 Sep 11.
Article
in English
| MEDLINE | ID: mdl-19584050
16.
Coenzyme A biosynthesis: an antimicrobial drug target.
FEMS Microbiol Rev
; 32(1): 56-106, 2008 Jan.
Article
in English
| MEDLINE | ID: mdl-18173393
17.
Toward a Stable and Potent Coenzyme A-Targeting Antiplasmodial Agent: Structure-Activity Relationship Studies of N-Phenethyl-α-methyl-pantothenamide.
ACS Infect Dis
; 6(7): 1844-1854, 2020 07 10.
Article
in English
| MEDLINE | ID: mdl-32375471
18.
Structure-Activity Relationships of Antiplasmodial Pantothenamide Analogues Reveal a New Way by Which Triazoles Mimic Amide Bonds.
ChemMedChem
; 13(24): 2677-2683, 2018 12 20.
Article
in English
| MEDLINE | ID: mdl-30370998
19.
Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation.
Eur J Med Chem
; 143: 1139-1147, 2018 Jan 01.
Article
in English
| MEDLINE | ID: mdl-29233590
20.
Antiplasmodial Mode of Action of Pantothenamides: Pantothenate Kinase Serves as a Metabolic Activator Not as a Target.
ACS Infect Dis
; 3(7): 527-541, 2017 07 14.
Article
in English
| MEDLINE | ID: mdl-28437604