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1.
Favipiravir induces HuNoV viral mutagenesis and infectivity loss with clinical improvement in immunocompromised patients.
Clin Immunol
; 259: 109901, 2024 02.
Article
in English
| MEDLINE | ID: mdl-38218209
2.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Lancet
; 401(10373): 281-293, 2023 01 28.
Article
in English
| MEDLINE | ID: mdl-36566761
3.
Model Based Estimation of Posaconazole Tablet and Suspension Bioavailability in Hospitalized Children Using Real-World Therapeutic Drug Monitoring Data in Patients Receiving Intravenous and Oral Dosing.
Antimicrob Agents Chemother
; 67(7): e0007723, 2023 07 18.
Article
in English
| MEDLINE | ID: mdl-37260401
4.
The Neonatal and Paediatric Pharmacokinetics of Antimicrobials study (NAPPA): investigating amoxicillin, benzylpenicillin, flucloxacillin and piperacillin pharmacokinetics from birth to adolescence.
J Antimicrob Chemother
; 78(9): 2148-2161, 2023 09 05.
Article
in English
| MEDLINE | ID: mdl-37531085
5.
Assessment of the nlmixr R package for population pharmacokinetic modeling: A metformin case study.
Br J Clin Pharmacol
; 89(1): 330-339, 2023 01.
Article
in English
| MEDLINE | ID: mdl-35976674
6.
Pharmacokinetic pharmacodynamic modeling of analgesics and sedatives in children.
Paediatr Anaesth
; 33(10): 781-792, 2023 10.
Article
in English
| MEDLINE | ID: mdl-37341161
7.
Favipiravir, lopinavir-ritonavir, or combination therapy (FLARE): A randomised, double-blind, 2 × 2 factorial placebo-controlled trial of early antiviral therapy in COVID-19.
PLoS Med
; 19(10): e1004120, 2022 10.
Article
in English
| MEDLINE | ID: mdl-36260627
8.
Applications of the hollow-fibre infection model (HFIM) in viral infection studies.
J Antimicrob Chemother
; 78(1): 8-20, 2022 12 23.
Article
in English
| MEDLINE | ID: mdl-36411255
9.
The impact of the COVID-19 pandemic on antimicrobial prescribing at a specialist paediatric hospital: an observational study.
J Antimicrob Chemother
; 77(4): 1185-1188, 2022 03 31.
Article
in English
| MEDLINE | ID: mdl-35134183
10.
Simultaneous pharmacokinetic/pharmacodynamic (PKPD) assessment of ampicillin and gentamicin in the treatment of neonatal sepsis.
J Antimicrob Chemother
; 77(2): 448-456, 2022 02 02.
Article
in English
| MEDLINE | ID: mdl-35107141
11.
Population Pharmacokinetics of Intranasal Dexmedetomidine in Infants and Young Children.
Anesthesiology
; 137(2): 163-175, 2022 08 01.
Article
in English
| MEDLINE | ID: mdl-35503980
12.
Access to palivizumab among children at high risk of respiratory syncytial virus complications in English hospitals.
Br J Clin Pharmacol
; 88(3): 1246-1257, 2022 03.
Article
in English
| MEDLINE | ID: mdl-34478568
13.
Comparative assessment of viral dynamic models for SARS-CoV-2 for pharmacodynamic assessment in early treatment trials.
Br J Clin Pharmacol
; 88(12): 5428-5433, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36040430
14.
General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
Br J Clin Pharmacol
; 88(12): 4985-4996, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36256514
15.
Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.
Br J Clin Pharmacol
; 88(12): 4965-4984, 2022 12.
Article
in English
| MEDLINE | ID: mdl-34180088
16.
Pharmacokinetic modeling and simulation to understand diamorphine dose-response in neonates, children, and adolescents.
Paediatr Anaesth
; 32(6): 716-726, 2022 06.
Article
in English
| MEDLINE | ID: mdl-35212432
17.
Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.
Antimicrob Agents Chemother
; 65(7): e0029321, 2021 06 17.
Article
in English
| MEDLINE | ID: mdl-33972238
18.
Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival.
Adv Funct Mater
; 31(37): 2104843, 2021 Sep 09.
Article
in English
| MEDLINE | ID: mdl-35712226
19.
Clinical pharmacokinetics and dose recommendations for posaconazole gastroresistant tablets in children with cystic fibrosis.
J Antimicrob Chemother
; 76(12): 3247-3254, 2021 11 12.
Article
in English
| MEDLINE | ID: mdl-34458906
20.
IV and oral fosfomycin pharmacokinetics in neonates with suspected clinical sepsis.
J Antimicrob Chemother
; 76(7): 1855-1864, 2021 06 18.
Article
in English
| MEDLINE | ID: mdl-33855449