Search | VHL CLAP/WR-PAHO/WHO

1.

Heme metabolism in nonerythroid cells.

Dunaway, Luke S; Loeb, Skylar A; Petrillo, Sara; Tolosano, Emanuela; Isakson, Brant E.

J Biol Chem ; 300(4): 107132, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38432636

2.

Unearthing FLVCR1a: tracing the path to a vital cellular transporter.

Fiorito, Veronica; Tolosano, Emanuela.

Cell Mol Life Sci ; 81(1): 166, 2024 Apr 06.

Article in English | MEDLINE | ID: mdl-38581583

3.

Duality of Nrf2 in iron-overload cardiomyopathy.

Federti, Enrica; Vinchi, Francesca; Iatcenko, Iana; Ghigo, Alessandra; Matte, Alessandro; Toya, Serge Cedrick Mbiandjeu; Siciliano, Angela; Chiabrando, Deborah; Tolosano, Emanuela; Vance, Steven Zebulon; Riccardi, Veronica; Andolfo, Immacolata; Iezzi, Manuela; Lamolinara, Alessia; Iolascon, Achille; De Franceschi, Lucia.

Haematologica ; 108(5): 1335-1348, 2023 05 01.

Article in English | MEDLINE | ID: mdl-36700398

4.

Divergent roles of haptoglobin and hemopexin deficiency for disease progression of Shiga-toxin-induced hemolytic-uremic syndrome in mice.

Pirschel, Wiebke; Mestekemper, Antonio N; Wissuwa, Bianka; Krieg, Nadine; Kröller, Sarah; Daniel, Christoph; Gunzer, Florian; Tolosano, Emanuela; Bauer, Michael; Amann, Kerstin; Heinemann, Stefan H; Coldewey, Sina M.

Kidney Int ; 101(6): 1171-1185, 2022 06.

Article in English | MEDLINE | ID: mdl-35031328

5.

Hemopexin and Cancer.

Fiorito, Veronica; Tolosano, Emanuela.

Int J Mol Sci ; 23(2)2022 Jan 17.

Article in English | MEDLINE | ID: mdl-35055182

6.

Heme and macrophages: a complicated liaison.

Tolosano, Emanuela.

Blood ; 141(25): 3015-3017, 2023 06 22.

Article in English | MEDLINE | ID: mdl-37347498

7.

Expression and purification of the heme exporter FLVCR1a.

Chiabrando, Deborah; Scietti, Luigi; Prajica, Adriana Georgiana; Bertino, Francesca; Tolosano, Emanuela; Magnani, Francesca.

Protein Expr Purif ; 172: 105637, 2020 08.

Article in English | MEDLINE | ID: mdl-32278001

8.

Hereditary Ataxia: A Focus on Heme Metabolism and Fe-S Cluster Biogenesis.

Chiabrando, Deborah; Bertino, Francesca; Tolosano, Emanuela.

Int J Mol Sci ; 21(11)2020 May 26.

Article in English | MEDLINE | ID: mdl-32466579

9.

Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells.

Ala, Ugo; Manco, Marta; Mandili, Giorgia; Tolosano, Emanuela; Novelli, Francesco; Provero, Paolo; Altruda, Fiorella; Fagoonee, Sharmila.

Int J Mol Sci ; 21(2)2020 Jan 16.

Article in English | MEDLINE | ID: mdl-31963158

10.

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation.

Beneduce, Elisabetta; Mattè, Alessandro; De Falco, Luigia; Cedrick, Serge; Tolosano, Emanuela; Chiabrando, Deborah; Siciliano, Angela; Iolascon, Achille; Narla, Mohandas; De Franceschi, Lucia.

Blood ; 130(Suppl_1): 9, 2017 Dec 07.

Article in English | MEDLINE | ID: mdl-31940663

11.

Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis.

Beneduce, Elisabetta; Matte, Alessandro; De Falco, Luigia; Mbiandjeu, Serge; Chiabrando, Deborah; Tolosano, Emanuela; Federti, Enrica; Petrillo, Sara; Mohandas, Narla; Siciliano, Angela; Babu, Wilson; Menon, Vijay; Ghaffari, Saghi; Iolascon, Achille; De Franceschi, Lucia.

Am J Hematol ; 94(1): 10-20, 2019 01.

Article in English | MEDLINE | ID: mdl-30252956

12.

Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception.

Chiabrando, Deborah; Castori, Marco; di Rocco, Maja; Ungelenk, Martin; Gießelmann, Sebastian; Di Capua, Matteo; Madeo, Annalisa; Grammatico, Paola; Bartsch, Sophie; Hübner, Christian A; Altruda, Fiorella; Silengo, Lorenzo; Tolosano, Emanuela; Kurth, Ingo.

PLoS Genet ; 12(12): e1006461, 2016 Dec.

Article in English | MEDLINE | ID: mdl-27923065

13.

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.

Vinchi, Francesca; Costa da Silva, Milene; Ingoglia, Giada; Petrillo, Sara; Brinkman, Nathan; Zuercher, Adrian; Cerwenka, Adelheid; Tolosano, Emanuela; Muckenthaler, Martina U.

Blood ; 127(4): 473-86, 2016 Jan 28.

Article in English | MEDLINE | ID: mdl-26675351

14.

Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation.

Castori, Marco; Morlino, Silvia; Ungelenk, Martin; Pareyson, Davide; Salsano, Ettore; Grammatico, Paola; Tolosano, Emanuela; Kurth, Ingo; Chiabrando, Deborah.

Am J Med Genet B Neuropsychiatr Genet ; 174(7): 732-739, 2017 Oct.

Article in English | MEDLINE | ID: mdl-28766925

15.

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage.

Ma, Bo; Day, Jason Patrick; Phillips, Harrison; Slootsky, Bryan; Tolosano, Emanuela; Doré, Sylvain.

J Neuroinflammation ; 13: 26, 2016 Feb 01.

Article in English | MEDLINE | ID: mdl-26831741

16.

Hypoxia controls Flvcr1 gene expression in Caco2 cells through HIF2α and ETS1.

Fiorito, Veronica; Neri, Francesco; Pala, Valentina; Silengo, Lorenzo; Oliviero, Salvatore; Altruda, Fiorella; Tolosano, Emanuela.

Biochim Biophys Acta ; 1839(4): 259-64, 2014.

Article in English | MEDLINE | ID: mdl-24576667

17.

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

Vinchi, Francesca; Ingoglia, Giada; Chiabrando, Deborah; Mercurio, Sonia; Turco, Emilia; Silengo, Lorenzo; Altruda, Fiorella; Tolosano, Emanuela.

Gastroenterology ; 146(5): 1325-38, 2014 May.

Article in English | MEDLINE | ID: mdl-24486949

18.

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation.

Mercurio, Sonia; Petrillo, Sara; Chiabrando, Deborah; Bassi, Zuni Irma; Gays, Dafne; Camporeale, Annalisa; Vacaru, Andrei; Miniscalco, Barbara; Valperga, Giulio; Silengo, Lorenzo; Altruda, Fiorella; Baron, Margaret H; Santoro, Massimo Mattia; Tolosano, Emanuela.

Haematologica ; 100(6): 720-9, 2015 Jun.

Article in English | MEDLINE | ID: mdl-25795718

19.

Acute-phase protein hemopexin is a negative regulator of Th17 response and experimental autoimmune encephalomyelitis development.

Rolla, Simona; Ingoglia, Giada; Bardina, Valentina; Silengo, Lorenzo; Altruda, Fiorella; Novelli, Francesco; Tolosano, Emanuela.

J Immunol ; 191(11): 5451-9, 2013 Dec 01.

Article in English | MEDLINE | ID: mdl-24154625

20.

Renal cells from spermatogonial germline stem cells protect against kidney injury.

De Chiara, Letizia; Fagoonee, Sharmila; Ranghino, Andrea; Bruno, Stefania; Camussi, Giovanni; Tolosano, Emanuela; Silengo, Lorenzo; Altruda, Fiorella.

J Am Soc Nephrol ; 25(2): 316-28, 2014 Feb.

Article in English | MEDLINE | ID: mdl-24136918

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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