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1.
"Affimer" synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation.
J Biol Chem
; 299(11): 105325, 2023 11.
Article
in English
| MEDLINE | ID: mdl-37805141
2.
Rapid Quantification of C. difficile Glutamate Dehydrogenase and Toxin B (TcdB) with a NanoBiT Split-Luciferase Assay.
Anal Chem
; 94(23): 8156-8163, 2022 06 14.
Article
in English
| MEDLINE | ID: mdl-35634999
3.
Selective Affimers Recognise the BCL-2 Family Proteins BCL-xL and MCL-1 through Noncanonical Structural Motifs*.
Chembiochem
; 22(1): 232-240, 2021 01 05.
Article
in English
| MEDLINE | ID: mdl-32961017
4.
Piggybacking on the Cholera Toxin: Identification of a CTB-Binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons.
Bioconjug Chem
; 32(10): 2205-2212, 2021 10 20.
Article
in English
| MEDLINE | ID: mdl-34565149
5.
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Blood
; 133(11): 1233-1244, 2019 03 14.
Article
in English
| MEDLINE | ID: mdl-30545831
6.
Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk.
Haematologica
; 106(6): 1616-1623, 2021 06 01.
Article
in English
| MEDLINE | ID: mdl-32354869
7.
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.
Proc Natl Acad Sci U S A
; 115(1): E72-E81, 2018 01 02.
Article
in English
| MEDLINE | ID: mdl-29247053
8.
Control of conformation in α-helix mimicking aromatic oligoamide foldamers through interactions between adjacent side-chains.
Org Biomol Chem
; 17(15): 3861-3867, 2019 04 10.
Article
in English
| MEDLINE | ID: mdl-30938392
9.
VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8.
Traffic
; 17(1): 53-65, 2016 Jan.
Article
in English
| MEDLINE | ID: mdl-26459808
10.
Site-Specific Labeling of Affimers for DNA-PAINT Microscopy.
Angew Chem Int Ed Engl
; 57(34): 11060-11063, 2018 08 20.
Article
in English
| MEDLINE | ID: mdl-29873161
11.
Antibody Mimetics for the Detection of Small Organic Compounds Using a Quartz Crystal Microbalance.
Anal Chem
; 89(5): 3051-3058, 2017 03 07.
Article
in English
| MEDLINE | ID: mdl-28192970
12.
A place for precision medicine in bladder cancer: targeting the FGFRs.
Future Oncol
; 12(19): 2243-63, 2016 Oct.
Article
in English
| MEDLINE | ID: mdl-27381494
13.
Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease.
J Inherit Metab Dis
; 38(4): 753-63, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25868665
14.
Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions.
Angew Chem Int Ed Engl
; 54(10): 2960-5, 2015 Mar 02.
Article
in English
| MEDLINE | ID: mdl-25651514
15.
Therapeutic drug monitoring of immunotherapies with novel Affimer-NanoBiT sensor construct.
Sens Diagn
; 3(1): 104-111, 2024 Jan 18.
Article
in English
| MEDLINE | ID: mdl-38249540
16.
Affimer reagents as tool molecules to modulate platelet GPVI-ligand interactions and specifically bind GPVI dimer.
Blood Adv
; 2024 Jun 05.
Article
in English
| MEDLINE | ID: mdl-38838227
17.
Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues.
PLoS One
; 18(3): e0283044, 2023.
Article
in English
| MEDLINE | ID: mdl-36928454
18.
Enzyme - Switch sensors for therapeutic drug monitoring of immunotherapies.
Biosens Bioelectron
; 237: 115488, 2023 Oct 01.
Article
in English
| MEDLINE | ID: mdl-37419072
19.
Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition.
Cell Rep
; 42(10): 113184, 2023 10 31.
Article
in English
| MEDLINE | ID: mdl-37776520
20.
Purification and Analysis of Circulating Lipid Particles.
Methods Mol Biol
; 2419: 193-212, 2022.
Article
in English
| MEDLINE | ID: mdl-35237966