Search | VHL CLAP/WR-PAHO/WHO

1.

The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.

Shum, Eleen Y; Jones, Samantha H; Shao, Ada; Chousal, Jennifer N; Krause, Matthew D; Chan, Wai-Kin; Lou, Chih-Hong; Espinoza, Josh L; Song, Hye-Won; Phan, Mimi H; Ramaiah, Madhuvanthi; Huang, Lulu; McCarrey, John R; Peterson, Kevin J; De Rooij, Dirk G; Cook-Andersen, Heidi; Wilkinson, Miles F.

Cell ; 165(2): 382-95, 2016 04 07.

Article in English | MEDLINE | ID: mdl-27040500

2.

Progression of the pluripotent epiblast depends upon the NMD factor UPF2.

Chousal, Jennifer N; Sohni, Abhishek; Vitting-Seerup, Kristoffer; Cho, Kyucheol; Kim, Matthew; Tan, Kun; Porse, Bo; Wilkinson, Miles F; Cook-Andersen, Heidi.

Development ; 149(21)2022 11 01.

Article in English | MEDLINE | ID: mdl-36255229

3.

Regulation of both transcription and RNA turnover contribute to germline specification.

Tan, Kun; Wilkinson, Miles F.

Nucleic Acids Res ; 50(13): 7310-7325, 2022 07 22.

Article in English | MEDLINE | ID: mdl-35776114

4.

SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis.

Lehtiniemi, Tiina; Bourgery, Matthieu; Ma, Lin; Ahmedani, Ammar; Mäkelä, Margareeta; Asteljoki, Juho; Olotu, Opeyemi; Laasanen, Samuli; Zhang, Fu-Ping; Tan, Kun; Chousal, Jennifer N; Burow, Dana; Koskinen, Satu; Laiho, Asta; Elo, Laura L; Chalmel, Frédéric; Wilkinson, Miles F; Kotaja, Noora.

Nucleic Acids Res ; 50(20): 11470-11491, 2022 11 11.

Article in English | MEDLINE | ID: mdl-36259644

5.

The Rhox gene cluster suppresses germline LINE1 transposition.

Tan, Kun; Kim, Matthew E; Song, Hye-Won; Skarbrevik, David; Babajanian, Eric; Bedrosian, Tracy A; Gage, Fred H; Wilkinson, Miles F.

Proc Natl Acad Sci U S A ; 118(23)2021 06 08.

Article in English | MEDLINE | ID: mdl-34083437

6.

Single-cell RNAseq analysis of testicular germ and somatic cell development during the perinatal period.

Tan, Kun; Song, Hye-Won; Wilkinson, Miles F.

Development ; 147(3)2020 02 03.

Article in English | MEDLINE | ID: mdl-31964773

7.

Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease.

Jaffrey, Samie R; Wilkinson, Miles F.

Nat Rev Neurosci ; 19(12): 715-728, 2018 12.

Article in English | MEDLINE | ID: mdl-30410025

8.

Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro.

Tan, Kun; Song, Hye-Won; Thompson, Merlin; Munyoki, Sarah; Sukhwani, Meena; Hsieh, Tung-Chin; Orwig, Kyle E; Wilkinson, Miles F.

Proc Natl Acad Sci U S A ; 117(30): 17832-17841, 2020 07 28.

Article in English | MEDLINE | ID: mdl-32661178

9.

A synonymous UPF3B variant causing a speech disorder implicates NMD as a regulator of neurodevelopmental disorder gene networks.

Domingo, Deepti; Nawaz, Urwah; Corbett, Mark; Espinoza, Josh L; Tatton-Brown, Katrina; Coman, David; Wilkinson, Miles F; Gecz, Jozef; Jolly, Lachlan A.

Hum Mol Genet ; 29(15): 2568-2578, 2020 08 29.

Article in English | MEDLINE | ID: mdl-32667670

10.

A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1.

Ramaiah, Madhuvanthi; Tan, Kun; Plank, Terra-Dawn M; Song, Hye-Won; Chousal, Jennifer N; Jones, Samantha; Shum, Eleen Y; Sheridan, Steven D; Peterson, Kevin J; Gromoll, Jörg; Haggarty, Stephen J; Cook-Andersen, Heidi; Wilkinson, Miles F.

EMBO Rep ; 20(2)2019 02.

Article in English | MEDLINE | ID: mdl-30573526

11.

Genetic paradox explained by nonsense.

Wilkinson, Miles F.

Nature ; 568(7751): 179-180, 2019 04.

Article in English | MEDLINE | ID: mdl-30962551

12.

How to activate a gene: decap its associated noncoding RNA.

Ramaiah, Madhuvanthi; Shum, Eleen Y; Wilkinson, Miles F.

Mol Cell ; 45(3): 271-3, 2012 Feb 10.

Article in English | MEDLINE | ID: mdl-22325347

13.

RNA Decay Factor UPF1 Promotes Protein Decay: A Hidden Talent.

M Plank, Terra-Dawn; Wilkinson, Miles F.

Bioessays ; 40(1)2018 Jan.

Article in English | MEDLINE | ID: mdl-29236296

14.

RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

Huang, Lulu; Lou, Chih-Hong; Chan, Waikin; Shum, Eleen Y; Shao, Ada; Stone, Erica; Karam, Rachid; Song, Hye-Won; Wilkinson, Miles F.

Mol Cell ; 43(6): 950-61, 2011 Sep 16.

Article in English | MEDLINE | ID: mdl-21925383

15.

Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.

Bruno, Ivone G; Karam, Rachid; Huang, Lulu; Bhardwaj, Anjana; Lou, Chih H; Shum, Eleen Y; Song, Hye-Won; Corbett, Mark A; Gifford, Wesley D; Gecz, Jozef; Pfaff, Samuel L; Wilkinson, Miles F.

Mol Cell ; 42(4): 500-10, 2011 May 20.

Article in English | MEDLINE | ID: mdl-21596314

16.

The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men.

Borgmann, Jennifer; Tüttelmann, Frank; Dworniczak, Bernd; Röpke, Albrecht; Song, Hye-Won; Kliesch, Sabine; Wilkinson, Miles F; Laurentino, Sandra; Gromoll, Jörg.

Hum Mol Genet ; 25(22): 4898-4910, 2016 11 15.

Article in English | MEDLINE | ID: mdl-28171660

17.

Nonsense shielding: protecting RNA from decay leads to cancer.

Wilkinson, Miles F; Cook-Andersen, Heidi.

EMBO J ; 38(3)2019 02 01.

Article in English | MEDLINE | ID: mdl-30679197

18.

The unfolded protein response is shaped by the NMD pathway.

Karam, Rachid; Lou, Chih-Hong; Kroeger, Heike; Huang, Lulu; Lin, Jonathan H; Wilkinson, Miles F.

EMBO Rep ; 16(5): 599-609, 2015 May.

Article in English | MEDLINE | ID: mdl-25807986

19.

Response to: X-linked miR-506 family miRNAs promote FMRP expression in mouse spermatogonia.

Ramaiah, Madhuvanthi; Tan, Kun; Plank, Terra-Dawn M; Song, Hye-Won; Chousal, Jennifer N; Jones, Samantha; Shum, Eleen Y; Sheridan, Steven D; Peterson, Kevin J; Gromoll, Jörg; Haggarty, Stephen J; Cook-Andersen, Heidi; Wilkinson, Miles F.

EMBO Rep ; 21(1): e49354, 2020 01 07.

Article in English | MEDLINE | ID: mdl-31808609

20.

Identification of novel post-transcriptional features in olfactory receptor family mRNAs.

Shum, Eleen Y; Espinoza, Josh L; Ramaiah, Madhuvanthi; Wilkinson, Miles F.

Nucleic Acids Res ; 43(19): 9314-26, 2015 Oct 30.

Article in English | MEDLINE | ID: mdl-25908788

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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