Search details
1.
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.
Cell
; 181(3): 590-603.e16, 2020 04 30.
Article
in English
| MEDLINE | ID: mdl-32272060
2.
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.
Nature
; 571(7764): 275-278, 2019 07.
Article
in English
| MEDLINE | ID: mdl-31181567
3.
A high-fidelity RNA-targeting Cas13 restores paternal Ube3a expression and improves motor functions in Angelman syndrome mice.
Mol Ther
; 31(7): 2286-2295, 2023 07 05.
Article
in English
| MEDLINE | ID: mdl-36805082
4.
A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.
Nat Methods
; 17(6): 600-604, 2020 06.
Article
in English
| MEDLINE | ID: mdl-32424272
5.
Prediction and Validation of Mouse Meiosis-Essential Genes Based on Spermatogenesis Proteome Dynamics.
Mol Cell Proteomics
; 20: 100014, 2021.
Article
in English
| MEDLINE | ID: mdl-33257503
6.
Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing.
Development
; 145(20)2018 10 17.
Article
in English
| MEDLINE | ID: mdl-30275281
7.
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model.
Acta Pharmacol Sin
; 44(11): 2342-2345, 2023 11.
Article
in English
| MEDLINE | ID: mdl-37402996
8.
Incorporating Machine Learning Strategies to Smart Gloves Enabled by Dual-Network Hydrogels for Multitask Control and User Identification.
ACS Sens
; 9(4): 1886-1895, 2024 Apr 26.
Article
in English
| MEDLINE | ID: mdl-38529839
9.
Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.
Nat Cell Biol
; 23(1): 99-108, 2021 01.
Article
in English
| MEDLINE | ID: mdl-33398178
10.
CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration.
Natl Sci Rev
; 7(5): 835-837, 2020 May.
Article
in English
| MEDLINE | ID: mdl-34692105
11.
A Cas-embedding strategy for minimizing off-target effects of DNA base editors.
Nat Commun
; 11(1): 6073, 2020 11 27.
Article
in English
| MEDLINE | ID: mdl-33247095
12.
Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and mice.
Natl Sci Rev
; 7(1): 92-101, 2020 Jan.
Article
in English
| MEDLINE | ID: mdl-34691481
13.
Allele-specific genome editing of imprinting genes by preferentially targeting non-methylated loci using Staphylococcus aureus Cas9 (SaCas9).
Sci Bull (Beijing)
; 64(21): 1592-1600, 2019 Nov 15.
Article
in English
| MEDLINE | ID: mdl-36659571
14.
Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.
Cell Rep
; 26(2): 302-312.e4, 2019 01 08.
Article
in English
| MEDLINE | ID: mdl-30625312
15.
Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors.
Genome Biol
; 20(1): 101, 2019 05 22.
Article
in English
| MEDLINE | ID: mdl-31118069
16.
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.
Nat Neurosci
; 21(3): 440-446, 2018 03.
Article
in English
| MEDLINE | ID: mdl-29335603
17.
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
Cell Res
; 27(7): 933-945, 2017 Jul.
Article
in English
| MEDLINE | ID: mdl-28585534
18.
Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos.
Protein Cell
; 12(9): 741-745, 2021 09.
Article
in English
| MEDLINE | ID: mdl-33797032
19.
Chlorogenic acid induced apoptosis and inhibition of proliferation in human acute promyelocytic leukemia HL60 cells.
Mol Med Rep
; 8(4): 1106-10, 2013 Oct.
Article
in English
| MEDLINE | ID: mdl-23982123
20.
Highly efficient base editing in human tripronuclear zygotes.
Protein Cell
; 8(10): 772-775, 2017 10.
Article
in English
| MEDLINE | ID: mdl-28875305
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