Search | VHL CLAP/WR-PAHO/WHO

1.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Li, Hanjie; van der Leun, Anne M; Yofe, Ido; Lubling, Yaniv; Gelbard-Solodkin, Dikla; van Akkooi, Alexander C J; van den Braber, Marlous; Rozeman, Elisa A; Haanen, John B A G; Blank, Christian U; Horlings, Hugo M; David, Eyal; Baran, Yael; Bercovich, Akhiad; Lifshitz, Aviezer; Schumacher, Ton N; Tanay, Amos; Amit, Ido.

Cell ; 176(4): 775-789.e18, 2019 02 07.

Article in English | MEDLINE | ID: mdl-30595452

2.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Li, Hanjie; van der Leun, Anne M; Yofe, Ido; Lubling, Yaniv; Gelbard-Solodkin, Dikla; van Akkooi, Alexander C J; van den Braber, Marlous; Rozeman, Elisa A; Haanen, John B A G; Blank, Christian U; Horlings, Hugo M; David, Eyal; Baran, Yael; Bercovich, Akhiad; Lifshitz, Aviezer; Schumacher, Ton N; Tanay, Amos; Amit, Ido.

Cell ; 181(3): 747, 2020 Apr 30.

Article in English | MEDLINE | ID: mdl-32359441

3.

Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.

van der Leun, Anne M; Hoekstra, Mirjam E; Reinalda, Luuk; Scheele, Colinda L G J; Toebes, Mireille; van de Graaff, Michel J; Chen, Linda Y Y; Li, Hanjie; Bercovich, Akhiad; Lubling, Yaniv; David, Eyal; Thommen, Daniela S; Tanay, Amos; van Rheenen, Jacco; Amit, Ido; van Kasteren, Sander I; Schumacher, Ton N.

Nat Chem Biol ; 17(11): 1139-1147, 2021 11.

Article in English | MEDLINE | ID: mdl-34504322

4.

Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.

van der Leun, Anne M; Traets, Joleen J H; Vos, Joris L; Elbers, Joris B W; Patiwael, Sanne; Qiao, Xiaohang; Machuca-Ostos, Mercedes; Thommen, Daniela S; Haanen, John B A G; Schumacher, Ton N M; Zuur, Charlotte L.

Cancer Discov ; 13(10): 2212-2227, 2023 Oct 05.

Article in English | MEDLINE | ID: mdl-37548431

5.

Harnessing human plasmacytoid dendritic cells as professional APCs.

Tel, Jurjen; van der Leun, Anne M; Figdor, Carl G; Torensma, Ruurd; de Vries, I Jolanda M.

Cancer Immunol Immunother ; 61(8): 1279-88, 2012 Aug.

Article in English | MEDLINE | ID: mdl-22294456

6.

The power to "di-sc-seq-t".

van der Leun, Anne M; Haanen, John B.

Cancer Cell ; 39(3): 299-301, 2021 03 08.

Article in English | MEDLINE | ID: mdl-33577786

7.

An atlas of intratumoral T cells.

van der Leun, Anne M; Schumacher, Ton N.

Science ; 374(6574): 1446-1447, 2021 Dec 17.

Article in English | MEDLINE | ID: mdl-34914514

8.

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.

Vos, Joris L; Elbers, Joris B W; Krijgsman, Oscar; Traets, Joleen J H; Qiao, Xiaohang; van der Leun, Anne M; Lubeck, Yoni; Seignette, Iris M; Smit, Laura A; Willems, Stefan M; van den Brekel, Michiel W M; Dirven, Richard; Baris Karakullukcu, M; Karssemakers, Luc; Klop, W Martin C; Lohuis, Peter J F M; Schreuder, Willem H; Smeele, Ludi E; van der Velden, Lilly-Ann; Bing Tan, I; Onderwater, Suzanne; Jasperse, Bas; Vogel, Wouter V; Al-Mamgani, Abrahim; Keijser, Astrid; van der Noort, Vincent; Broeks, Annegien; Hooijberg, Erik; Peeper, Daniel S; Schumacher, Ton N; Blank, Christian U; de Boer, Jan Paul; Haanen, John B A G; Zuur, Charlotte L.

Nat Commun ; 12(1): 7348, 2021 12 22.

Article in English | MEDLINE | ID: mdl-34937871

9.

CD8⁺ T cell states in human cancer: insights from single-cell analysis.

van der Leun, Anne M; Thommen, Daniela S; Schumacher, Ton N.

Nat Rev Cancer ; 20(4): 218-232, 2020 04.

Article in English | MEDLINE | ID: mdl-32024970

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Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.

Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.

Harnessing human plasmacytoid dendritic cells as professional APCs.

The power to "di-sc-seq-t".

An atlas of intratumoral T cells.

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.

CD8⁺ T cell states in human cancer: insights from single-cell analysis.