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1.
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions-A calibration approach.
Biom J
; 61(3): 488-502, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30175405
2.
Early metabolic response in sequential FDG-PET/CT under cetuximab is a predictive marker for clinical response in first-line metastatic colorectal cancer patients: results of the phase II REMOTUX trial.
Br J Cancer
; 119(2): 170-175, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29961759
3.
POSITIVE study: physical exercise program in non-operable lung cancer patients undergoing palliative treatment.
BMC Cancer
; 16: 499, 2016 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27430336
4.
Synthesis of 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides and their evaluation as ligands for NMDA receptor glycine binding site.
J Enzyme Inhib Med Chem
; 31(4): 664-73, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26114309
5.
Some Issues of Sample Size Calculation for Time-to-Event Endpoints Using the Freedman and Schoenfeld Formulas.
J Biopharm Stat
; 25(6): 1285-311, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25629760
6.
Chemotherapy for advanced pancreatic adenocarcinoma in elderly patients (≥70 years of age): a retrospective cohort study at the National Center for Tumor Diseases Heidelberg.
Pancreatology
; 14(3): 211-5, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24854617
7.
Scaffold hopping approach towards various AFQ-056 analogs as potent metabotropic glutamate receptor 5 negative allosteric modulators.
Bioorg Med Chem Lett
; 23(23): 6370-6, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24125886
8.
Discovery, synthesis, and structure-activity relationships of 2-aminoquinazoline derivatives as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators.
Bioorg Med Chem Lett
; 23(16): 4493-500, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23856046
9.
Investigation of the GnRH antagonist degarelix isomerization in biological matrices.
Pharmacol Res Perspect
; 11(4): e01117, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37455491
10.
A phase II study for metabolic in vivo response monitoring with sequential 18FDG-PET-CT during treatment with the EGFR-monoclonal-antibody cetuximab in metastatic colorectal cancer: the Heidelberg REMOTUX trial.
BMC Cancer
; 12: 108, 2012 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22439666
11.
Lentiviral vector integration profiles differ in rodent postmitotic tissues.
Mol Ther
; 19(4): 703-10, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21364536
12.
Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy.
Mol Ther
; 19(11): 2031-9, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21862999
13.
Sequential FDG-PET and induction chemotherapy in locally advanced adenocarcinoma of the Oesophago-gastric junction (AEG): the Heidelberg Imaging program in Cancer of the oesophago-gastric junction during Neoadjuvant treatment: HICON trial.
BMC Cancer
; 11: 266, 2011 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21702914
14.
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy.
J Clin Invest
; 117(8): 2225-32, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17671652
15.
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.
J Clin Invest
; 117(8): 2241-9, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17671654
16.
Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists.
Bioorg Med Chem Lett
; 20(16): 4911-7, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20638278
17.
A randomized multicentre phase II trial comparing adjuvant therapy in patients with interferon alpha-2b and 5-FU alone or in combination with either external radiation treatment and cisplatin (CapRI) or radiation alone regarding event-free survival - CapRI-2.
BMC Cancer
; 9: 160, 2009 May 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19470159
18.
Short time to progression under first-line chemotherapy is a negative prognostic factor for time to progression and residual survival under second-line chemotherapy in advanced pancreatic cancer.
Oncology
; 73(5-6): 335-9, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-18497506
19.
Safety of the use of Tissucol Duo S in cardiovascular surgery: retrospective analysis of 2149 patients after coronary artery bypass grafting.
Eur J Cardiothorac Surg
; 32(4): 560-6, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17363261
20.
Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts.
EMBO Mol Med
; 9(7): 918-932, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28526679