Detalles de la búsqueda
1.
New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights.
J Enzyme Inhib Med Chem
; 38(1): 2281260, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37994663
2.
Synthesis and SARs study of novel spiro-oxindoles as potent antiproliferative agents with CDK-2 inhibitory activities.
Arch Pharm (Weinheim)
; 356(8): e2300185, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37253118
3.
Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity.
Molecules
; 28(19)2023 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37836817
4.
Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies.
Int J Mol Sci
; 23(19)2022 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36233160
5.
Exploiting the Chiral Ligands of Bis(imidazolinyl)- and Bis(oxazolinyl)thiophenes-Synthesis and Application in Cu-Catalyzed Friedel-Crafts Asymmetric Alkylation.
Molecules
; 26(23)2021 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34885989
6.
Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents.
Molecules
; 26(20)2021 Oct 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34684885
7.
Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs.
Molecules
; 26(23)2021 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34885853
8.
Bimetallic Iron-Palladium Catalyst System as a Lewis-Acid for the Synthesis of Novel Pharmacophores Based Indole Scaffold as Anticancer Agents.
Molecules
; 26(8)2021 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33921334
9.
Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity.
J Enzyme Inhib Med Chem
; 35(1): 692-701, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32156165
10.
Synthesis of a New Class of Spirooxindole-Benzo[b]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors.
Molecules
; 25(20)2020 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33066293
11.
Corrigendum to "Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma" [Bioorg. Chem. 129 (2022) 106124].
Bioorg Chem
; 143: 107012, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38071087
12.
Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2-p53 interaction.
Bioorg Chem
; 86: 598-608, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30802707
13.
Synthesis of new thiazolo-pyrrolidine-(spirooxindole) tethered to 3-acylindole as anticancer agents.
Bioorg Chem
; 82: 423-430, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30508794
14.
Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase.
Molecules
; 24(12)2019 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31242688
15.
Anticancer Indole-Based Chalcones: A Structural and Theoretical Analysis.
Molecules
; 24(20)2019 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31623155
16.
Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study.
Molecules
; 24(7)2019 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30987350
17.
Catalytic asymmetric synthesis of indole derivatives as novel α-glucosidase inhibitors in vitro.
Bioorg Chem
; 79: 350-354, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29807208
18.
Synthesis of pyrimidine-2,4,6-trione derivatives: Anti-oxidant, anti-cancer, α-glucosidase, ß-glucuronidase inhibition and their molecular docking studies.
Bioorg Chem
; 68: 72-9, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27454620
19.
3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model.
Int J Mol Sci
; 17(5)2016 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27144563
20.
Synthesis of Pyrazole-Thiobarbituric Acid Derivatives: Antimicrobial Activity and Docking Studies.
Molecules
; 21(10)2016 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27735850