[Behavior of nucleolar organizers in the normal cervix, human papilloma virus infection and cervico-uterine cancer]. / Comportamiento de los organizadores nucleolares en el cervix normal, infección por virus del papiloma humano y cáncer cervicouterino.

Thirty five cervical biopsies were divided into four groups: 5 cases normal cervix, 10 cases with papillomavirus without atypias (HPVIO), 10 cases with human papillomavirus with atypias (HPVIA) and 10 cases with squamous carcinoma. With the colloidal silver technique, the proteins associated with nucleolar organizers were stained; they were found to increase significantly in number in the groups studied being lowest in the normal cervix and highest in the biopsies with carcinoma. The number of nucleolar organizers in HPVIO in our study was found to be similar to that in cervical intraepithelial neoplasia I (CIN I), according to Egan and the number in HPVIA similar to that in CIN II, suggesting that HPVIO is a low risk lesion and HPVIA a high risk lesion for cervical carcinoma.

[Transitional cell tumor of the ovary. Revision of a 20-year surgical material of the department of pathology at the Mexico General Hospital]. / Tumor de células transicionales del ovario. Revisión del material quirúrgico de la unidad de patología del Hospital General de México, en un periodo de 20 años.

Of 127,483 histopathological reports from biopsies and surgical specimens, 1490 ovarian tumors were found, including benign and malignant neoplasms; of these there were eight cases of transitional cell tumors, meaning a frequency of 0.54%. The patient's ages ranged from 33 to 70 years with an average of 49.4. The histopathological diagnoses were benign Brenner tumor in five cases, a proliferating Brenner tumor and Brenner of low malignancy grade in two cases, and transitional cell carcinoma in one case. The predominant location was left ovary. Four were solid tumors, one was solid-cystic corresponding to the proliferating tumor of low grade malignancy and to the transitional cell carcinoma. The size of tumors varied from 1.2 to 25 cm (in diameter) with on average of 11.7. The larger tumors corresponded to the cystic and the more aggressive histological patterns, suggesting that a large predominantly cystic tumor merits extensive sampling in order to exclude malignancy.

[Advanced gestational choriocarcinoma. A clinical-pathological study of 40 cases]. / Coriocarcinoma gestacional avanzado. Estudio clínico patológico de 40 casos.

Forty two cases of advanced gestational choriocarcinoma were examined, with 4 of these patients being hospitalized for less than 24 hours. Given the non specific and atypical nature of the symptomatology, it was correctly diagnosed in 20 of these cases. In the other 22 cases where the predominant clinical status was established as a result of the localized invasion of neighboring structures or through metastasis, a variety of diagnoses were given, including uterine cervical carcinoma, endometrial carcinoma, pulmonary metastasis, brain tumor, bleeding of the gastrointestinal tract. The 20 patient diagnosed with choriocarcinoma were treated in the following manner: nine were operated for hysterectomies, with one of these also receiving an omentectomy, seven more were given chemotherapy treatment based upon methotrexate, and the remaining for were simply stabilized, which produced unfavorable results in that they survived from one to twenty weeks longer, with an average on only five weeks.

[Papillary mesothelioma of the ovarian surface. Presentation of a case]. / Mesotelioma papilar de la superficie ovárica. Presentación de un caso.

A case of a 41 years old woman with a benign mesothelioma of the superficial epithelium of the ovary, is presented. The tumor was expanded at the bottom of the cul de sac. It did not invade the rectum, uterus or vagina and it has not been recurrent, and there are not metastasis after y 6 years post operatively. Morphologically, the neoplasia is created by papillae invested with cells of mesothelial appearance, which contain a small amount of glycogen and acids mucopolysaccharide. With immunoperoxidase keratin is shown and at the electronic microscope some desmosomes and microvillus, are identified. The histogenesis of the tumor examined, and the differential diagnosis between mesothelioma and superficial papillary carcinoma of the ovary, is considered.

[Giant bronchiectasis caused by chronic inhalation of porcine hair]. / Bronquiectasias gigantes por inhalación crónica del pelo porcino.

A rare case of gigantic bronchiectasis consecutive to chronic inhalation of pork hair (hog's bristle) is presented. The possible pathogenic mechanisms are discussed. The case was subject to surgical resection of the affected lung segment, lingula.

[Mortality in geriatric patients in the Hospital General of Mexico]. / Mortalidad en pacientes geriátricos del Hospital General de México.

In order to define the main diseases of the elderly and a possible changes of mortality causes at Hospital General of Mexico, SSA, the authors studied 586 autopsy reports of individuals over sixty years old, deceased between 1960 and 1965 and of 625 individuals of similar characteristics deceased between 1981 and 1985. The analysis of diseases showed qualitative and quantitative changes in the ten principal causes of death at each period: some of the most frequent diseases in the 60's, for instance, amebiasis, were not included among the then principal causes of death in the 80's. On the other hand, malignant neoplasms persisted as one of the principal death causes in both periods, but the most frequent carcinoma in the 60's, gastric carcinoma, was substituted in the 80's by bronchogenic carcinoma. This study suggests that great technical and sanitary interventions are necessary to promote health of third age persons, an increasing but poorly protected population in our country.