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1.
Design, synthesis, and antitumor efficacy of novel 5-deazaflavin derivatives backed by kinase screening, docking, and ADME studies.
J Enzyme Inhib Med Chem
; 38(1): 2220570, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37341389
2.
Antitumor and multikinase inhibition activities of some synthesized coumarin and benzofuran derivatives.
Arch Pharm (Weinheim)
; 355(6): e2100327, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35285986
3.
Design, Synthesis, Antitumor Activity and Molecular Docking Study of Novel 5-Deazaalloxazine Analogs.
Molecules
; 25(11)2020 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32481639
4.
Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
Bioorg Med Chem
; 27(7): 1308-1319, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30792101
5.
Synthesis and molecular docking study of new benzofuran and furo[3,2-g]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors.
Bioorg Chem
; 76: 487-500, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29310080
6.
Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells.
Bioorg Med Chem
; 25(8): 2423-2436, 2017 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28291685
7.
Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action.
Bioorg Med Chem
; 25(20): 5637-5651, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28916158
8.
Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability.
Molecules
; 21(2)2016 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26867188
9.
Synthesis, biological evaluation, and docking studies of new 2-furylbenzimidazoles as anti-angiogenic agents: part II.
Arch Pharm (Weinheim)
; 347(4): 291-304, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24497234
10.
Synthesis, docking and biological activities of novel hybrids celecoxib and anthraquinone analogs as potent cytotoxic agents.
Int J Mol Sci
; 15(12): 22580-603, 2014 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25490139
11.
Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic acids.
Bioorg Med Chem
; 20(3): 1259-70, 2012 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22225915
12.
In-Situ Implant Formulation of Laurate and Myristate Prodrugs of Dolutegravir for Ultra-Long Delivery.
J Pharm Sci
; 111(8): 2312-2321, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35296412
13.
In-use stability assessment of FDA approved metformin immediate release and extended release products for N-Nitrosodimethylamine and dissolution quality attributes.
Int J Pharm
; 623: 121923, 2022 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35750279
14.
Design and Synthesis of 4-O-Podophyllotoxin Sulfamate Derivatives as Potential Cytotoxic Agents.
Evid Based Complement Alternat Med
; 2021: 6672807, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33574882
15.
A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors.
J Comput Aided Mol Des
; 24(1): 57-75, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20039101
16.
Dual Targeting of VEGFR2 and C-Met Kinases via the Design and Synthesis of Substituted 3-(Triazolo-thiadiazin-3-yl)indolin-2-one Derivatives as Angiogenesis Inhibitors.
ACS Omega
; 5(30): 18872-18886, 2020 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32775889
17.
Exosomes are the Driving Force in Preparing the Soil for the Metastatic Seeds: Lessons from the Prostate Cancer.
Cells
; 9(3)2020 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32121073
18.
HER2 Kinase-Targeted Breast Cancer Therapy: Design, Synthesis, and In Vitro and In Vivo Evaluation of Novel Lapatinib Congeners as Selective and Potent HER2 Inhibitors with Favorable Metabolic Stability.
J Med Chem
; 63(24): 15906-15945, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33314925
19.
Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition.
Cancers (Basel)
; 12(8)2020 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32824235
20.
Targeting CDC7 sensitizes resistance melanoma cells to BRAFV600E-specific inhibitor by blocking the CDC7/MCM2-7 pathway.
Sci Rep
; 9(1): 14197, 2019 10 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31578454