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1.
Croat Med J ; 52(6): 703-8, 2011 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-22180269

RESUMEN

AIM: To investigate the distribution of 17 Y-short tandem repeat (STR) loci in the population of the Cukurova region of Turkey. METHODS: In the period between 2009 and 2010, we investigated the distribution of 17 Y-STRs in a sample of 249 unrelated healthy men from the Cukurova region of Turkey. Genomic DNA was extracted with InstaGene matrix and Y-STRs were determined using the AmpFISTR Yfiler PCR amplification kit. Gene and haplotype diversity values were estimated using the Arlequin software. To compare our data to other populations, population pairwise genetic distances and associated probability values were calculated using the Y Chromosome Haplotype Reference Database Web site software. RESULTS: At 17 Y-STR loci we detected 148 alleles. The lowest gene diversity in this region was 0.51 for DYS391 and the highest 0.95 for DYS385a/b. Haplotype diversity was 0.9997±0.0004. We compared our data with haplotype data of other Turkish populations and no significant differences were found, except with Ankara population (Φst=0.025, P=0.018). Comparisons were also made with the neighboring populations using analysis of molecular variance of the Y-STR loci genetic structure and our population was nearest to Lenkoran-Azerbaijani (Φst=0.012, P=0.068) and Iranian Ahvaz population (Φst=0.007, P=0.173), followed by Greek (Φst=0.025, P=0.000) and Russian (Φst=0.048, P=0.000) population. Other countries like Portugal, Spain, Italy, Egypt, Israel (Palestinian Authority Area), and Taiwan showed a high genetic distance from our population. CONCLUSION: Our study showed that Y-STR polymorphisms were a powerful discrimination tool for routine forensic applications and could be used in genealogical investigations.


Asunto(s)
Cromosomas Humanos Y/genética , Frecuencia de los Genes/genética , Haplotipos/genética , Repeticiones de Microsatélite/genética , Alelos , Variación Genética/genética , Humanos , Masculino , Polimorfismo Genético/genética , Turquía/epidemiología
2.
Forensic Sci Int Genet ; 24: 176-179, 2016 09.
Artículo en Inglés | MEDLINE | ID: mdl-27479879

RESUMEN

Despite its large geographic and population size only little is known about the mitochondrial (mt)DNA make up of Turkey.orensically relevant data are almost completely absent in the literature. We analyzed the mtDNA control region of 224 volunteers from South Eastern Turkey and compared the data to populations from neighboring countries. The haplotypes will be made available via the EMPOP database (EMP00670) and contribute to the body of forensic mtDNA data.


Asunto(s)
ADN Mitocondrial/genética , Genética de Población , Haplotipos , Bases de Datos de Ácidos Nucleicos , Humanos , Análisis de Secuencia de ADN , Turquía
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