Assessment of lifestyle and coping strategies among asthmatic patients during the Covid-19 crisis.

BACKGROUND: COVID-19 can cause an asthma attack by triggering asthma symptoms, such as wheezing, chest tightness, and difficulty breathing, which are distressing for patients and can cause anxiety. Additionally, it can progress to pneumonia or other severe lung diseases. OBJECTIVES: Therefore, this study aimed to assess the coping strategies and lifestyle modifications among patients with asthma during the COVID-19 crisis. METHODS: A descriptive comparative design was conducted on 300 adult patients with bronchial asthma at the Alexandria Main University Hospital's chest disease outpatient clinic. Three tools were used for data (including biosocio-demographic characteristics of patients with asthma, the effect of the COVID-19 crisis on the lifestyle of patients with asthma, and how patients with asthma cope with COVID-19) collection. RESULTS: This study revealed that more than two-thirds of patients with asthma did not have COVID-19, while more than one-quarter had COVID-19. More than two-thirds had reasonable asthma control, and more than half had neutral coping with their asthma and the COVID-19 crisis. Half of the studied patients had coped neutrally with their asthma during the COVID-19 crisis, and more than half coped neutrally with the COVID-19 crisis. CONCLUSION: These findings indicate that all stressors faced by patients with respiratory diseases during the COVID-19 crisis and psychological, social, and health support that should be provided to these patients during the pandemic require further investigation.

Nursing faculty perceptions of simulation culture readiness in Saudi universities: a cross-sectional study.

BACKGROUND: Academic programs are increasing simulation-based learning in Saudi Arabia during COVID-19 pandemic; however, there is limited knowledge about these universities' simulation culture readiness. Thus, the purpose of this study was to explore faculty perceptions of the readiness to integrate simulation into nursing programs. METHODS: This cross-sectional correlational study recruited faculty members in four nursing colleges at Saudi universities using the simulation culture organizational readiness survey 36-item questionnaire. A total of 88 faculty members from four Saudi universities were included. Descriptive, Pearson's correlation, independent sample t-test, and analysis of covariance analysis were utilized in this study. RESULTS: Nearly 39.8% and 38.6% of the participants had Moderately and Very Much overall readiness for the simulation-based education (SBE), respectively. There were significant correlations between the summary impression on simulation culture readiness measures and simulation culture organizational readiness survey subscales (p < 0.001). Three simulation culture organizational readiness survey subscales (defined need and support for change, readiness for culture change, and time, personnel, and resource readiness) and the overall readiness for SBE were correlated with age, years since highest degree, years of experience in academia, and years using simulation in teaching (p < 0.05). The sustainability practices to embed culture subscale and summary impression were only correlated significantly with the number of years using simulation in teaching (p = 0.016 and 0.022, respectively). Females had a significantly higher mean in the sustainability practices to embed culture subscale (p = 0.006) and the overall readiness for simulation-based education (p = 0.05). Furthermore, there were significant differences among the highest degree in the overall readiness for SBE (p = 0.026), summary impression (p = 0.001), the defined need and support subscale (p = 0.05), the sustainability practices to embed culture subscale (p = 0.029), and the time, personnel, and resource readiness subscale (p = 0.015). CONCLUSIONS: Favorable simulation culture readiness results suggest great opportunities to advance clinical competencies in academic curricula and optimize educational outcomes. Nurse academic leaders should identify needs and resources to enhance simulation readiness and encourage the integration of simulation in nursing education.

The use of complementary and alternative medicine among women with breast cancer in Saudi Arabia.

PURPOSE: The purpose of the study was to explore the frequency of use of complementary and alternative medicine (CAM) therapies among women with breast cancer in Saudi Arabia. DESIGN: A descriptive cross-sectional study design was used with face-to-face interviews using a structured questionnaire. SAMPLE: A convenient sample of 85 Saudi women with breast cancer who were undergoing cancer treatment was recruited from the Oncology Department of King Faisal Hospital, Jeddah, Kingdom of Saudi Arabia. METHODS: Using structured questionnaire "Use of Complementary Therapies Survey," consisted of diet and nutritional supplements, stress-reducing therapies, and other traditional treatments. RESULT: Participants were predominantly married (76.5%), resided in an urban area (83.5%), unemployed (62%), and about half reported no income (49.4%). The mean age was 48 years. All participants reported using at least three or more CAM therapies (mean = 21.15, SD = 8.85) since their diagnosis. There were significant correlations between other CAM use and time since diagnosis (rs = -0.33, p < .05). The highest usage of dietary and nutritional supplements occurred with honey, olive oil, antioxidants, Fennel flower seeds, and ginger. The highest stress reducing CAM techniques included reading the Holy Qur'ãn, and praying. For other traditional CAM therapies, positive thinking and relaxation techniques were the most frequent methods reported by women. Other CAM treatments involved ZamZam water and listening to music. CONCLUSIONS: The use of complementary therapies among Saudi women with breast cancer is highly prevalent, with a predominance of interventions of religious background, indicating the strong influence of religion on peoples' lives, especially when people are faced with a life-threatening illness. The results of this study will guide future studies examining the efficacy of CAM on symptom management in Saudi Arabian women with breast cancer and other types of cancer.

The Relationship Between Knowledge and Practice of Postreproductive Women Toward Prevention and Screening of Breast and Cervical Cancer in Saudi Arabia.

Introduction Cervical cancer and breast cancer are the major causes of mortality among women worldwide, and the burden of cancer incidence is increasing exponentially. The aim of this study was to assess the relationship between knowledge and practice of postreproductive women toward prevention and screening of breast and cervical cancer in Saudi Arabia.  Methods A quantitative, descriptive, cross-sectional study was conducted using a convenience sampling method. One hundred and twenty-eight participants completed the online survey. The questionnaire consists of four main sections: sociodemographic data, obstetrical history, knowledge, and practice of breast and cervical cancer. The correlation coefficient and chi-square test were used to analyze the data. Results Nearly 40% of the participants had good knowledge of the risk factors of breast cancer; 80% had good knowledge of early warnings of breast cancer; 66% had fair knowledge of prevention measures of breast cancer; and 68% had good knowledge of prevention measures of breast cancer. Only 23% of participants had poor knowledge of risk factors of cervical cancer, whereas 62% had fair knowledge of early signs and early screening methods of cervical cancer. The majority of the respondents (85%) had good knowledge of prevention measures for cervical cancer; however, less than one-third of the participants (31%) and 39% had poor or fair practice regarding screening and prevention of breast and cervical cancer, respectively. A significant relationship between practice and knowledge was found as well as a significant relationship between practice and educational level as the p-value was less than 0.05. Conclusion Despite having a comprehensive understanding of avoidable malignancies and screening methods, postreproductive women's utilization of breast and cervical cancer examinations was inadequate. Hence, continuous awareness programs are needed to help women modify their habits and early detections.

Molecular docking analysis of KRAS inhibitors for cancer management.

The majority of human tumors are characterized by abnormal signaling caused by oncogenic RAS proteins. KRAS is a member of the RAS family and is currently one of the most thoroughly researched targets for cancer treatment due to its prevalence in a variety of deadly malignancies. Targeting the KRAS protein, which plays a crucial role in regulating cell growth, differentiation, and apoptosis, shows great potential as a strategy for fighting cancer. Herein, in silico screening of 530 natural compounds against KRAS protein was performed. The top-scoring hits, namely ZINC32502206, ZINC98363763, ZINC85645815, and ZINC98364259 displayed a robust affinity towards KRAS as evidenced by their respective binding affinity values of -10.50, -10.01, -9.80, and -9.70 kcal/mol, respectively which were notably higher than that of the control compound AMG 510 (-9.10 kcal/mol). Through virtual screening and visual inspection, it was observed that these hits effectively interacted with the essential residues located within the active site of KRAS. Based on the findings of this study, it can be inferred that these compounds may have the potential to be employed in the treatment of cancer by targeting KRAS.

Maintaining Clinical Training Continuity during COVID-19 Pandemic: Nursing Students' Perceptions about Simulation-Based Learning.

BACKGROUND: Simulation-based learning (SBL) in nursing education is an innovative pedagogical approach that has significantly improved nursing education. Adopting SBL provides a controlled environment for meeting educational objectives without the risk of harm to real patients. Given that social distancing is required during the coronavirus disease (COVID-19) pandemic, SBL is a suitable alternative to clinical training for nursing students to learn and acquire the required clinical competencies. The study aimed to describe the effectiveness of SBL as a complete substitute for clinical experience from the perspective of students. This cross-sectional descriptive survey investigated students' perceptions regarding the description of the effectiveness of SBL in four nursing colleges at four different universities across the Kingdom of Saudi Arabia. SETTINGS: Four nursing colleges at four different universities across the Kingdom of Saudi Arabia. Participants included nursing students who attended simulation sessions. Data were collected by distributing a self-administrated online questionnaire, the Modified Simulation Effectiveness Tool (SET-M), which is a 19-item. RESULTS: Approximately two-thirds of the participants were in their third (30.4%) and fourth (44.5%) academic year. The highest student presentation was for Site 1 (39.5%) and Site 2 (32.5%). Significant differences existed in all domains according to sex and university (p ≤ 0.001). There was a significant difference in relation to the level of agreement for pre-briefing, scenario, and debriefing domains (<0.001). CONCLUSIONS: SBL is a valuable teaching strategy that enhances nursing students' self-awareness, self-confidence, clinical performance, and efficiency in performing procedures with considerable gender variation. Female students had more positive perceptions toward simulation effectiveness.

Fatigue and Sleep Disturbance among Breast Cancer Patients during Treatment in Saudi Arabia.

Background: Fatigue and sleep disturbances are highly prevalent side effects encountered during treatment by patients with breast cancer, and they affect women's quality of life. Most studies investigating sleep and exhaustion in cancer patients provide evidence that supports a strong connection between different sleep parameters and fatigue associated with cancer. Objective: This study was to assess the level of fatigue and sleep disturbance in breast cancer patients during treatment in Saudi Arabia. Method: A descriptive cross-sectional study design was conducted on breast cancer patients undergoing treatment in Saudi Arabia. The data were collected through convenience sampling of patients. The study involved self-administered questionnaires comprising three categories: demographic data, perceived Pittsburgh Sleep Quality Index (PSQI), and Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F). A total of 101 participants took part in this study. The significant statistical test was determined at a 95% confidence interval and at p < 0.05. Results: Half of the study participants were aged between 30 and 50 years. Significant differences were found in fatigue and sleep disturbance among BC patients during treatment in Saudi Arabia. A high prevalence of fatigue was found at 21.8%, and 5% of participants experienced sleep disturbance. Conclusions: Breast cancer patients in Saudi Arabia have a low overall global quality of life. The patients experience poor sleep quality and fatigue, which suggests that during treatment, patients need to be assessed routinely for these symptoms to prevent or reduce fatigue and sleep disturbance. Sleep disturbance might be correlated with fatigue.

Prevalence of depression in patients with end-stage renal disease undergoing hemodialysis in Saudi Arabia: A cross-sectional study.

Background: A hemodialysis is a treatment option for patients with End-Stage Renal Disease (ESRD). However, patients undergoing hemodialysis three times per week may experience psychological issues, including depression, which are highly prevalent among patients. Unfortunately, most healthcare providers fail to recognize the symptoms of depression due to overlap with other somatic symptoms; thus, depression remains undiagnosed. Objective: This study aimed to estimate the prevalence of depression and compare the differences in depression symptoms according to the sociodemographic characteristics of patients with ESRD undergoing hemodialysis. Method: A descriptive, cross-sectional study was conducted from August to October 2021 with a total of 132 hemodialysis patients using the Beck Depression Inventory (BDI II) questionnaire to examine symptoms of depression at multiple health centers in Jeddah. Descriptive statistics, Mann-Whitney U, Kruskal-Wallis, Post-hoc analysis using Conover tests were used for data analysis. Results: The prevalence of depression in hemodialysis patients was 51.5%, 25.8%, 15.9%, and 6.8%, with minimal, mild, moderate, and severe symptoms, respectively. Depression exhibited a significant relationship with sex (p = 0.034), with females showing higher mean depression scores than males. Additionally, depression scores were statistically significant across the different levels of education (p = 0.019), with the mean depression scores significantly highest in subjects who had only primary school level of education. Furthermore, the most common symptoms associated with depression were found to be energy loss and fatigue. Conclusion: Depression prevalence was relatively low among patients with ESRD undergoing hemodialysis, and a loss of energy and fatigue were the most common symptoms correlated with depression. Hence, nurses should be trained on how to routinely use psychological screening scales among patients with ESRD undergoing hemodialysis.

Nurses' Knowledge and Anxiety Levels toward COVID-19 in Saudi Arabia.

Background: In the battle against the Coronavirus Disease 2019 (COVID-19) pandemic, medical care staff, especially nurses, are at a higher risk of encountering psychological health issues and distress, such as stress, tension, burdensome indications, and, most importantly, fear. They are also at higher risk of becoming infected and transmitting this virus. In Saudi Arabia, it was noticed that the healthcare workforce suffered from anxiety, and that this more evident in women than men. Objective: This study aimed to assess the knowledge of nurses regarding COVID-19 and the level of anxiety toward the COVID-19 outbreak in the current pandemic situation. Design: A cross-sectional design was used and a validated self-administered online questionnaire with a set of questions related to COVID-19 was distributed to 87 participating nurses. Results: The results showed that more than half of the nurses (71.90%) had an adequate and good knowledge about the causes, transmission, symptoms, treatment, and death rate of COVID-19. The main sources of information for the nurses were social media (51.7%) and the World Health Organization and the Ministry of Health (36.8%). Conclusions: The results allowed the conclusion that, though the nurses had satisfactory knowledge about COVID-19, more than 50% of them experienced mental health issues such as anxiety. To address this, along with providing more knowledge about COVID-19, nurses should be supported in managing their anxiety.

Discovering the Use of Complementary and Alternative Medicine in Oncology Patients: A Systematic Literature Review.

BACKGROUND: Patients with cancer pursue all possible opportunities of effective remedies. In Saudi Arabia, most patients have tried complementary medicine during their cancer treatment plan; however, some complementary medicines might pose a danger to health. In Arab countries, studies regarding the use of complementary medicines and the intentions behind using complementary medicines among cancer patients are inadequate and all but nonexistent. The aim of this review was to focus on demographic, prevalence, and reasons for complementary and alternative medicine use among patients with cancer. METHODS: A rigorous literature search was conducted for articles published in the English language, using the search terms "complementary and alternative medicine," "oncology," "malignancy" AND "cancer patients" in five scientific databases, namely, Medical Literature On-Line (MEDLINE), PubMed, Web of Science, Psychology Information (PsycINFO), and Google Scholar, from 2010 to 2020. RESULTS: Of the 13,160 studies returned from the search, only 12 were eligible and included in this review. The combined prevalence for using complementary and alternative medicines across all studies totaled 25%-80% of cancer patients for the treatment of their cancers. Natural products, including vitamins and minerals, herbal products, and relaxation, were the most common type of complementary and alternative medicines used. The reason for using complementary and alternative medicines was reported to be their helpfulness in recovering, healing, and improving health. Most of the studies mentioned that participants obtained their complementary and alternative medicines from multiple sources, including the media, family and friends, and physicians. CONCLUSION: The use of complementary and alternative medicines in cancer patients can be inferred as an attempt to investigate all possibilities, a manifestation of a coping style, or an illustration of unmet desires in the cancer management continuum. Anyhow, there should be adequate communication between healthcare providers and patients, which is crucial for establishing a trusting healthcare provider-patient relationship. Relevance to clinical practice. It is crucial that healthcare providers explore the use of complementary and alternative medicines with their cancer patients, as well as educating them about the possible usefulness of therapies based on the available evidence.

Prevalence of Low Back Pain and Associated Risk Factors among Nurses at King Abdulaziz University Hospital.

AIM: To determine the prevalence of LBP and the associated risk factors among nurses at King Abdulaziz University Hospital (KAUH). METHODS: A cross-sectional study design was adopted with a convenience sample of 234 nurses recruited from nine different departments at KAUH in Jeddah, Saudi Arabia. Participants completed the questionnaire, which had two parts: Part I: Socio-demographic data, medical factors, and work-related factors; and Part II: Standardized Nordic Musculoskeletal Questionnaire was used to obtain data. Data collection was carried out from March to April 2020. Data were analyzed using the SPSS version 22. RESULTS: Cumulative prevalence of LBP was 82.9%, annual prevalence was 85.5%, while one-week prevalence of LBP was 53.6%. The factor significantly associated with LBP over the past 12 months was manual lifting of patients (p = 0.030). Nurses working in surgical wards had higher prevalence of LBP. About 24.7% of them changed their working unit, hospitalization was necessary for 11.9%, and 39.8% sought medical care. CONCLUSIONS: The findings from this study may better enable policymakers to adopt certain strategies toward reducing the burdens and challenges of LBP among nurses.

The Level of Lymphedema Awareness among Women with Breast Cancer in the Kingdom of Saudi Arabia.

BACKGROUND: Lymphedema is a condition in which excessive fluid accumulates in soft tissues. It is a common complication of breast cancer treatments. It can lead to serious consequences and interfere with the activity of daily living. This study aimed to determine the level of awareness of breast-cancer-related lymphedema (BCRL) among women with breast cancer in the Kingdom of Saudi Arabia. This was a descriptive quantitative cross-sectional design that included a convenience sample of women diagnosed with breast cancer in the Kingdom of Saudi Arabia. Data were collected by distributing a self-administrated online questionnaire consisting of four parts, including demographic data (five items), the status of education about BCRL (three items), basic medical history of breast cancer (six items), and BCRL level of awareness of risk factors and management (nine items). RESULTS: In total, 95 out of 135 of participants did not know about lymphedema, 119 of the participants (88.1%) did not receive any explanation about the possibility of lymphedema from their medical team before surgery, and 121 of them (89.6%) did not receive it after surgery. The most significant factor affecting participants' level of awareness regarding BCRL was the lack of information about the possibility of BCRL occurrence, which was not provided to them by the medical team. RECOMMENDATION: Early and continuous education for future management is essential to prevent problems related to BCRL and improve quality of life.

Effects of Postpartum Fatigue and Depressive Cognitions on Life Satisfaction and Quality of Life in Arab Postpartum Women: The Intervening Role of Resourcefulness.

The purpose of this study is to explore the relationships among postpartum fatigue (PPF), depressive cognitions, resourcefulness, quality of life, and life satisfaction in Arab postpartum mothers. A conceptual framework is used in this study based on the middle range theory of resourcefulness, which Zauszniewski developed in 2006. The study is a cross-sectional descriptive design with 123 postpartum women who had given birth within the past six months. used WhatsApp and Facebook for recruitment. developed the self-administered online survey in Qualtrics and collected data from 6 January 2017, to 6 February 2017. Correlation analysis is used to address the research aim and used the P value of 0.05 to determine the significance of the results. There were significant correlations among depressive cognitions and resourcefulness, life satisfaction, and quality of life; there were also significant correlations between PPF and life satisfaction, as well as among resourcefulness, quality of life, and life satisfaction. The results of this study emphasized the importance of assessing depressive symptoms and PPF in mothers early in the postpartum period. The results may contribute to designing future intervention studies aimed toward decreasing the risk of mothers with PPF developing more serious depressive symptoms.

Assessment of Mothers' Knowledge, Attitudes, and Practices Regarding Childhood Vaccination during the First Five Years of Life in Saudi Arabia.

AIM: This study's aim was to assess the knowledge, attitudes, and practices of mothers regarding childhood vaccination during the first five years of children's lives in Saudi Arabia. METHOD: A cross-sectional, descriptive study was conducted with the application of convenience sampling, and 262 questionnaires were completed by Saudi mothers who had children aged 5 years or younger. RESULTS: The majority of the participants were aged 25-31 years (57%), 61% held a bachelor's degree, and 60.3% had children aged 2-5 years. The knowledge score was 86%, 2492 out of a total score of 2893; the attitude score was 89.1%, 973 out of a total score of 1052; the practice score was 80.5%, 1059 out of a total score of 1315. There was no evidence of an association (p > 0.05) between the knowledge, attitudes, and practice of mothers regarding vaccination and their sociodemographic aspects. CONCLUSION: The Saudi mothers in our sample were knowledgeable, with positive attitudes regarding vaccination, and they demonstrated good practices. This might be explained by the higher educational level of our sample. RECOMMENDATIONS: We recommend using multiple educational methods to support the practice of mothers regarding the management of complications of vaccinations.

The Perceptions of Nurses and Nursing Students Regarding Family Involvement in the Care of Hospitalized Adult Patients.

Over the past few decades, there have been concerns regarding the humanization of healthcare and the involvement of family members in patients' hospital care. The attitudes of hospitals toward welcoming families in this respect have improved. In Arab culture, the main core of society is considered to be the family, not the individual. The objective behind involving family in patient care is to meet patients' support needs. Consequently, this involvement affects nurses and their attitudes toward the importance of family involvement in patient care. OBJECTIVES: To describe nurses' and nursing students' perceptions of family involvement in the care of hospitalized adult patients in Saudi Arabia. DESIGN: This study used a quantitative descriptive cross-sectional design. The data were collected using a convenience sampling survey via social media. RESULTS: A total of 270 participants (staff and students) took part in this study, including 232 (85.9%) females and 38 (14.1%) males. Moreover, a high percentage of participants (78.8%) acknowledged that family presence strongly affected the improvement of the patient's condition. However, 69.3% of participants thought that involving family members during special care processes or cardiopulmonary resuscitation (CPR) would be traumatizing for these individuals. Moreover, there was a significant diffidence between the attitudes of the nurses and nursing students toward family involvement and the number of years of employment (F = 3.60, p < 0.05). On the contrary, there were insignificant differences between the attitudes of the nurses and nursing students toward family involvement and their gender, nationality, age, education level, and years of work experience in Saudi Arabia (p > 0.05). Furthermore, the regression analysis showed a significant negative correlation between nurses' years of employment and their support of family involvement in patient care (ß = -0.20, SE = 0.08, t = -2.70, p = 0.01). CONCLUSIONS: Nurses with more experience showed no support for family involvement in patient care. We have to consider the clinical barriers that affect nurses' support for family involvement in patient-centered care, such as hospital polices, guidelines, and the model used for family-centered care integration in the hospital system to facilitate the interaction between healthcare providers and family members.