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1.
Safety and efficacy of pyronaridine-artesunate paediatric granules in the treatment of uncomplicated malaria in children: insights from randomized clinical trials and a real-world study.
Malar J
; 23(1): 61, 2024 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38418982
2.
Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.
Clin Infect Dis
; 74(2): 180-188, 2022 01 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33983371
3.
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.
PLoS Med
; 18(6): e1003669, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34129601
4.
Pharmacokinetic interaction between pyronaridine-artesunate and metoprolol.
Antimicrob Agents Chemother
; 58(10): 5900-8, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25070091
5.
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Proc Natl Acad Sci U S A
; 108(11): 4400-5, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21300861
6.
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials.
Malar J
; 12: 70, 2013 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23433102
7.
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials.
Br J Clin Pharmacol
; 75(2): 524-37, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22759078
8.
Community-based management of a five-arm randomised clinical trial in COVID-19 outpatients in South Africa: challenges and opportunities.
Trials
; 24(1): 635, 2023 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37794489
9.
Community health workers in clinical research at the example of a phase IIIb/ IV antimalarial drug trial conducted in five African countries.
Int J Infect Dis
; 137: 114-117, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37871675
10.
Review of pyronaridine anti-malarial properties and product characteristics.
Malar J
; 11: 270, 2012 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22877082
11.
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial.
Lancet Microbe
; 3(8): e598-e605, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35654079
12.
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial.
EBioMedicine
; 86: 104322, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36332361
13.
Identification of an antimalarial synthetic trioxolane drug development candidate.
Nature
; 430(7002): 900-4, 2004 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-15318224
14.
Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.
Exp Parasitol
; 113(3): 197-200, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16458301
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