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Sci Rep ; 13(1): 352, 2023 01 07.
Artículo en Inglés | MEDLINE | ID: mdl-36611091

RESUMEN

Kawasaki disease (KD) is one of the most common vasculitides of early childhood. There are no previous studies on KD in Cyprus. The aim of this study was to evaluate the epidemiology of KD in Cyprus, risk factors for resistance to treatment and the development of cardiac complications. This is a retrospective multicenter study of pediatric patients with KD hospitalized between January 2000 and-December 2019. The data were collected from medical records. A total of 136 patients with KD were included in the study. 83% of patients were < 5 years of age and 10% were < 6 months. Thirty patients (22%) developed coronary artery lesions. Serum sodium ≤ 133 mmol/L, albumin ≤ 3.2 g/dl, ALT ≥ 80 U/L and neutrophils percentage ≥ 80% at diagnosis, were identified as risk factors for resistance to IVIG. Clinical and epidemiological characteristics of KD in Cyprus population were similar to those reported in the literature. Although the majority of cases received appropriate treatment in time, cardiac complications still occurred.


Asunto(s)
Cardiopatías , Síndrome Mucocutáneo Linfonodular , Niño , Humanos , Preescolar , Lactante , Síndrome Mucocutáneo Linfonodular/tratamiento farmacológico , Síndrome Mucocutáneo Linfonodular/epidemiología , Síndrome Mucocutáneo Linfonodular/complicaciones , Inmunoglobulinas Intravenosas/uso terapéutico , Chipre/epidemiología , Estudios Retrospectivos , Factores de Riesgo , Cardiopatías/complicaciones
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