Detalles de la búsqueda
1.
A framework for chemical safety assessment incorporating new approach methodologies within REACH.
Arch Toxicol
; 96(3): 743-766, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35103819
2.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Arch Toxicol
; 96(12): 3407-3419, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36063173
3.
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator.
Crit Rev Toxicol
; 44(1): 64-82, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24180433
4.
A microfluidic thyroid-liver platform to assess chemical safety in humans.
ALTEX
; 40(1): 61-82, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35536601
5.
A rodent thyroid-liver chip to capture thyroid toxicity on organ function level.
ALTEX
; 40(1): 83-102, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35791291
6.
Nervous system development related gene expression regulation in the zebrafish embryo after exposure to valproic acid and retinoic acid: A genome wide approach.
Toxicol Lett
; 384: 96-104, 2023 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37451652
7.
Dynamic regulation of gene expression and morphogenesis in the zebrafish embryo test after exposure to all-trans retinoic acid.
Reprod Toxicol
; 115: 8-16, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36375755
8.
Retinoic acid signaling pathway perturbation impacts mesodermal-tissue development in the zebrafish embryo: Biomarker candidate identification using transcriptomics.
Reprod Toxicol
; 119: 108404, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37207909
9.
Risk assessment of endocrine active chemicals: identifying chemicals of regulatory concern.
Regul Toxicol Pharmacol
; 64(1): 143-54, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22735369
10.
Science based guidance for the assessment of endocrine disrupting properties of chemicals.
Regul Toxicol Pharmacol
; 59(1): 37-46, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20858523
11.
Liverbeads: a practical and relevant in vitro model for gene induction investigations.
Drug Metab Dispos
; 38(9): 1598-604, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20551240
12.
Murine models for evaluating the allergenicity of novel proteins and foods.
Regul Toxicol Pharmacol
; 54(3 Suppl): S52-7, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19100305
13.
Correlation between protein accumulation profiles and conventional toxicological findings using a model antiandrogenic compound, flutamide.
Toxicol Sci
; 97(1): 81-93, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17311803
14.
Evaluation of the antiandrogenic effects of flutamide, DDE, and linuron in the weanling rat assay using organ weight, histopathological, and proteomic approaches.
Toxicol Sci
; 100(1): 54-65, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17686919
15.
Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes.
Biochim Biophys Acta
; 1745(1): 48-58, 2005 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16085054
16.
Androgens and postmeiotic germ cells regulate claudin-11 expression in rat Sertoli cells.
Endocrinology
; 146(3): 1532-40, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15591150
17.
Alteration of transforming growth factor-beta signaling system expression in adult rat germ cells with a chronic apoptotic cell death process after fetal androgen disruption.
Endocrinology
; 146(12): 5135-43, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16166221
18.
Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide.
Endocrinology
; 144(2): 648-61, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12538628
19.
Alteration of lactate production and transport in the adult rat testis exposed in utero to flutamide.
Mol Cell Endocrinol
; 206(1-2): 137-46, 2003 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-12943996
20.
17alpha-methyltestosterone: 28-day oral toxicity study in the rat based on the "Enhanced OECD Test Guideline 407" to detect endocrine effects.
Toxicology
; 192(2-3): 119-37, 2003 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-14580781