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1.
Sensors (Basel) ; 19(10)2019 May 17.
Artículo en Inglés | MEDLINE | ID: mdl-31109019

RESUMEN

This paper illustrates a methodology to get a reliable estimation of the local wave properties, based on the reconstruction of the motion of a moving sailboat by means of GNSS receivers installed on board and an original kinematic positioning approach. The wave parameters reconstruction may be used for many useful practical purposes, e.g. to improve of autopilots, for real-time control systems of ships, to analyze and improve the performance of race sailboats, and to estimate the local properties of the waves. A Class 40 oceanic vessel (ECO40) left from the port of "Riva di Traiano" located close to Rome (Italy) on 19 October 2014 to perform a non-stop sailing alone around the world in energy and food self-sufficiency. The proposed system was installed on ECO40 and the proposed method was applied to estimate the wave properties during a storm in the Western Mediterranean Sea. The results compared against two sets of hindcast data and wave buoy records demonstrated the reliability of the method.

2.
RNA Biol ; 12(7): 690-700, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25970317

RESUMEN

Treatment of leukemia cells with 1,25-dihydroxyvitamin D3 may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant for myeloid differentiation, we profiled the expression of mRNAs and microRNAs associated to the low- and high-density ribosomal fractions in leukemic cells and in their differentiated monocytic counterpart. Intersection between mRNAs shifted across the fractions after treatment with putative target genes of modulated microRNAs showed a series of molecular networks relevant for the monocyte cell fate determination, as for example the post-transcriptional regulation of the Polo-like kinase 1 (PLK1) by miR-22-3p and let-7e-5p.


Asunto(s)
Diferenciación Celular , Redes Reguladoras de Genes , Células Precursoras de Granulocitos/citología , Monocitos/citología , Procesamiento Postranscripcional del ARN , ARN Mensajero/metabolismo , Proteínas de Ciclo Celular/metabolismo , Colecalciferol/metabolismo , Células Precursoras de Granulocitos/metabolismo , Células HL-60 , Humanos , Leucemia/metabolismo , MicroARNs/metabolismo , Monocitos/metabolismo , Proteínas Serina-Treonina Quinasas/metabolismo , Proteínas Proto-Oncogénicas/metabolismo , Quinasa Tipo Polo 1
3.
Inf. psiquiátr ; (203): 57-64, ene.-mar. 2011. graf
Artículo en Español | IBECS (España) | ID: ibc-104283

RESUMEN

El burnout (en castellano «quemado») en los lugares de trabajo es un problema complejo que incluye factores de diferente origen en relación que puede ser con el individuo o bien con las condiciones objetivas del ambiente de trabajo; no es un problema que aparezca deforma aguda, sino al contrario, va haciéndolo de forma gradual. Es un proceso, y sus síntomas se presentan después de un determinado período de tiempo en el que se han mantenido unas condiciones de estrés, y se manifiesta con un agotamiento crónico, actitud de cinismo y desarraigo del trabajo. El auxiliar geriátrico, que se encuentra en permanente contacto con problemas como la enfermedad crónica sobre todo mental, es uno de los ejemplos más absolutos de profesional de riesgo de burnout y exige una respuesta de atención y soporte por parte de la organización. En la experiencia descrita el compromiso de la organización ha conseguido disminuir las discrepancias entre las personas y el trabajo, permitiendo al auxiliar geriátrico una mejor adaptación con el ambiente y un mayor equilibrio con todo elequipo de trabajo (AU)


Job burnout is a complex problem, which entails different factors whose origins are to be searched both within the individual and the objective work conditions; it isn’t a sudden process, but it is rather subject to a gradual development. Therefore job burnout is a process characterized by symptoms that begin to emerge after a prolonged exposure to stressful work conditions; it evolves contently and gradually and it manifests itself in the form of a chronic nervous breakdown, cynics and total detachment from work. The geriatric social worker, who is continuously faced with dilemmas such as illness chronicity, especially psychiatric disorders, gives us the example par excellence of a geriatric operator who is at high risk for job burnout and who requires the organization he works for to provide him with the support he needs and the possibility to share his experience. In the described experience, the effort made by the organization has appeared to be of high significance in reducing the discrepancy existing between the person and the job allowing the social worker to better adapt to the environment and to find a greater balance within the professional setting (AU)


Asunto(s)
Humanos , Servicios de Salud para Ancianos , Agotamiento Profesional/epidemiología , Asistentes de Enfermería/psicología , Estrés Psicológico/epidemiología , Relaciones Profesional-Paciente , Carga de Trabajo
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