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1.
Clin Exp Dermatol ; 47(1): 57-62, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34240451

RESUMEN

BACKGROUND: Vascular malformations are a complex pathology with few treatment options. In previously published studies, oral sirolimus (rapamycin) has shown promising results in the treatment of low-flow vascular malformations, but its usefulness in high-flow vascular malformations is controversial. AIM: To evaluate the efficacy and safety of sirolimus for the treatment of high-flow vascular malformations in real-life practice. METHODS: In a unit specializing in vascular anomalies, patients treated with oral sirolimus for high-flow vascular malformations were located by consulting the drug dispensations. Reviewing the electronic medical records, data on patient demographics, vascular malformation characteristics, treatments, toxicity and clinical course were collected and statistically analysed. RESULTS: Nine patients with vascular malformations were included: eight had arteriovenous malformation and one had arteriovenous fistula. Six of these malformations were isolated while three were part of a syndrome. Sirolimus was initiated at a dosage of 1-4 mg/day to be taken as a single dose. Partial response was observed in eight of the nine patients (88.9%) with high-flow vascular malformation, while worsening was observed in the remaining patient. The treatment was well tolerated and at the most recent follow-up, five patients remained on treatment with oral sirolimus. CONCLUSION: Our results show that oral sirolimus is a well-tolerated therapeutic option, with an excellent safety profile, which can be useful in the long-term stabilization of patients with high-flow vascular malformations. Single-daily dosage may improve long-term adherence to treatment without worsening its effectiveness.


Asunto(s)
Sirolimus/administración & dosificación , Malformaciones Vasculares/tratamiento farmacológico , Administración Oral , Adolescente , Adulto , Niño , Femenino , Hemodinámica , Humanos , Masculino , Flujo Sanguíneo Regional , Sirolimus/efectos adversos , Resultado del Tratamiento , Malformaciones Vasculares/fisiopatología , Adulto Joven
2.
Actas Dermosifiliogr ; 113(8): 804-807, 2022 Sep.
Artículo en Inglés, Español | MEDLINE | ID: mdl-35513036

RESUMEN

Ophthalmological complications are uncommon in dermatologic surgery. Nonetheless, all surgeons should know the basics of recognizing, preventing, and treating the 4 complications addressed in this article from the series 'Safety in Dermatologic Procedures'. The first complication that surgeons should be familiar with is eye damage due to chemical irritants. This is a common complication in operating rooms given the presence of irritant substances and the performance of procedures in the eyebrow and eyelid region. The second complication is laser-induced eye damage. In this case, eye protection with safety glasses or eye caps is crucial. The third complication is accidental eyeball perforation, which can occur during certain surgical procedures. The fourth and final complication is retinal artery vasospasm or embolism due to drugs or filler materials. This complication is rare but important to recognize, as early treatment can prevent permanent blindness.

3.
Clin Exp Dermatol ; 46(2): 314-318, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32572993

RESUMEN

Vascular malformations classification may pose a diagnostic challenge for physicians. In the early stages, they are diagnosed clinically mainly by visual inspection. For a deeper analysis, Doppler ultrasonography is the preferred technique to determine the haemodynamic behaviour of the anomaly. However, this imaging method is not always available and it requires trained operators to acquire and interpret the images. There is a lack of portable and user-friendly systems that may help physicians in the assessment of vascular malformations. We propose a new diagnostic procedure, more affordable and easier to use, based on a portable thermal camera. This technique provides information about temperature, which has been found to be correlated with the flow rate of the lesion. In our study, > 60 vascular malformations of previously diagnosed patients were analysed with a thermal camera to classify them into low-flow and high-flow malformations. The value was 1 for both sensitivity and specificity of this technique.


Asunto(s)
Termografía/instrumentación , Termografía/estadística & datos numéricos , Malformaciones Vasculares/diagnóstico , Velocidad del Flujo Sanguíneo/fisiología , Temperatura Corporal/fisiología , Diagnóstico Diferencial , Hemodinámica/fisiología , Humanos , Sensibilidad y Especificidad , Termografía/economía , Termografía/métodos , Ultrasonografía Doppler/métodos , Ultrasonografía Doppler/normas , Malformaciones Vasculares/clasificación , Malformaciones Vasculares/patología
4.
Actas Dermosifiliogr ; 104(2): 148-55, 2013 Mar.
Artículo en Inglés, Español | MEDLINE | ID: mdl-22840242

RESUMEN

BACKGROUND AND OBJECTIVE: Although dermatology has traditionally been practiced through outpatient consultation, hospitalized patients often have dermatologic problems. The aim of this study was to describe and quantify the volume of interdepartmental consultation of the dermatology department of Hospital Universitario Virgen del Rocío. MATERIAL AND METHODS: In this year-long prospective observational cohort study of 429 patients we used a specific data collection form to record information on consultations for patients admitted between July 2010 and June 2011. RESULTS: The 429 consultations over the 12 months of study accounted for 1.56% of all first consultations with a dermatologist during the period. A mean of 1.75 new patients were attended each day. The mean (SD) age of the patients was 52.63 (19) years, and the ratio of men to women was 1.21. Immunocompromised patients accounted for more than a third of the cohort. The medical specialties consulting most often were internal medicine (n=115) and hematology (n=66). The most frequent diagnoses were inflammatory skin conditions (36.2%) and infectious skin diseases (26.5%). DISCUSSION AND CONCLUSIONS: To date, the role of interdepartmental consultation in dermatology has been little studied. Our results suggest that dermatology plays a fundamental role within the hospital. We have identified the most common skin problems in hospitalized patients and their clinical course.


Asunto(s)
Atención Ambulatoria , Derivación y Consulta/estadística & datos numéricos , Enfermedades de la Piel , Centros de Atención Terciaria , Estudios de Cohortes , Dermatología , Femenino , Humanos , Pacientes Internos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Enfermedades de la Piel/diagnóstico , Enfermedades de la Piel/terapia , España
5.
Actas Dermosifiliogr ; 104(10): 890-6, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23809583

RESUMEN

BACKGROUND: Dystrophic epidermolysis bullosa (DEB) is a rare disease that represents a heavy burden for both the patient and the health care system. There are currently no data on the prevalence of DEB in Spain. OBJECTIVE: To determine the prevalence of DEB in Spain. METHODS: We used data from 3 incomplete population-based sources (hospital dermatology departments, diagnostic laboratories performing antigenic mapping, genetic testing or both, and the Spanish Association of Epidermolysis Bullosa Patients [DEBRA]) and combined them using the 3-source capture-recapture methodology. RESULTS: We identified 152 living DEB patients. The estimated prevalence of DEB was 6.0 cases per million (95% CI, 4.2-11.8) in adults and 15.3 (95% CI, 10.4-40.8) in children under 18 years of age. The data indicated that 77% of the patients were not being followed up in specialized centers of reference; 65% had not had a genetic diagnosis, and 76% were not members of DEBRA. CONCLUSIONS: The prevalence of DEB in Spain is 6.0 patients per million (95% CI, 4.2-11.8), a figure higher than previous estimates in many areas, but similar to those found in other southern Europe countries. The north-south difference may represent real geographic differences in prevalence, but it might be due to the fact that most of the data come from registries with a lower than expected catchment. Many patients are not being followed up in centers of reference, do not have genetic diagnosis, and are not members of patients' associations, suggesting that there is room for considerable improvement in their care.


Asunto(s)
Epidermólisis Ampollosa Distrófica/epidemiología , Epidermólisis Ampollosa Distrófica/terapia , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Estudios Transversales , Necesidades y Demandas de Servicios de Salud/estadística & datos numéricos , Humanos , Lactante , Persona de Mediana Edad , Prevalencia , Estudios Prospectivos , Mejoramiento de la Calidad , España/epidemiología , Adulto Joven
6.
Actas Dermosifiliogr ; 102(7): 510-6, 2011 Sep.
Artículo en Español | MEDLINE | ID: mdl-21514550

RESUMEN

BACKGROUND AND OBJECTIVES: Recent reports have described the successful use of propranolol to treat severe hemangiomas of infancy. The few case series that have been reported, however, have included only a small number of patients. The aim of this study was to describe the results of oral propranolol treatment for severe hemangiomas of infancy in terms of treatment outcome and the occurrence of adverse events. PATIENTS AND METHODS: A descriptive, observational study was undertaken in a series of children with severe hemangiomas of infancy seen in the pediatric dermatology unit at Hospital Universitario Virgen del Rocío in Seville, Spain between July 2008 and December 2009. Patients were included if they had hemangiomas in the proliferative phase or involuting lesions with substantial residual deformity. All children were treated with oral propranolol (2 mg/kg/d) and followed until September 2010. Epidemiologic characteristics were analyzed along with treatment response at 3, 6, 9, 12, and 18 months; adverse events were also recorded at those times. RESULTS: Thirty-six hemangiomas were treated in 28 patients. Propranolol treatment was effective in all cases, with a good or complete response in 88.2% at 6 months. Effects were apparent within a few hours of treatment, which was effective in both growing and involuting hemangiomas. In ulcerated hemangiomas, the mean healing time was 61 days. Adverse events were mild and self-limiting. Only 2 patients discontinued treatment due to hypotension. CONCLUSIONS: In the majority of cases, oral propranolol produced rapid and sustained improvements in hemangiomas of infancy and shortened the natural course of the disease with few side effects. However, no significant reductions in symptoms or healing time were observed in ulcerated hemangiomas.


Asunto(s)
Hemangioma/tratamiento farmacológico , Propranolol/administración & dosificación , Neoplasias Cutáneas/tratamiento farmacológico , Administración Oral , Preescolar , Femenino , Humanos , Lactante , Masculino , Índice de Severidad de la Enfermedad
7.
Artículo en Inglés, Español | MEDLINE | ID: mdl-34052200

RESUMEN

BACKGROUND: There are several therapeutic options for infantile haemangiomas (IH). Propranolol is used according to a pivotal trial. We aimed to describe the characteristics of IH in clinical practice, including the therapies used, and to compare the characteristics of patients treated with propranolol with those of the trial to assess its external validity. METHODS: Consecutive patients attending 12 Spanish hospitals from June 2016 to October 2019 were included (n=601). RESULTS: The mean age was 3.9 (SD:1.9) months, with a 2:1 female-to-male ratio. Most IHs were localized (82%, 495), superficial (64%, 383) and located in the face (25%, 157) and trunk (31%, 188). Median size was 17 (IR: 10-30) x 12 (IR: 7-20) mm. Complications were found in 16 (3%) patients. Treatment was initiated for 52% (311). Most patients received timolol (76%, 237); propranolol was reserved for complications or high-risk IHs. Aesthetic impairment was the main reason for starting therapy (64%, 199). Several characteristics of the patients and IHs treated with propranolol are similar to those of the pivotal clinical trial, but 1/3 of IHs did not reach the minimum diameter to meet the inclusion criteria, and important prognostic information was not reported. CONCLUSIONS: As most patients receive treatment for aesthetic impairment, there is a need to better understand the aesthetic results of therapies and to increase evidence on the use of timolol, which is currently the most common therapy. Propranolol is being used in a population generally similar to that of the trial; however, this statement cannot be definitely confirmed.

9.
Cir Pediatr ; 23(2): 92-4, 2010 Apr.
Artículo en Español | MEDLINE | ID: mdl-21298917

RESUMEN

INTRODUCTION: PHACES syndrome associates a segmental facial hemangioma with cerebral malformations, aortic branches/cranial arteries anomalies, cardiac defects, eye anomalies or ventral wall defects. The aim of this study is to analyze our experience with this syndrome. MATERIAL AND METHODS: Retrospective study of the cases seen at our unit in the last year. RESULTS: We treat 4 cases; 3 girls and 1 child. Besides the segmental hemangioma they presented: 3 vascular cerebral malformations; 2 structural cardiopathies; 2 cerebral malformations, 1 microftalmia. We did not find ventral wall defects. A case received treatment with two cycles of metilprednisolone i.v. and oral prednisone, with favourable course; two cases received initial treatment with oral prednisone continued of oral propanolol in rising pattern up to 2 mg/kg/day, Obtaining both the detention of the tumour growth and regression of the lesion, with very good tolerance. A 7-year-old patient has been treated with colouring pulse laser for her residual lesions. CONCLUSIONS: When we see a segmental facial hemangioma we must perform a wide diagnostic study in order to discard a PHACES syndrome. Multidisciplinar approach to the patient by a wide expert's group gets an earlier diagnose and improves the outcome. Propranolol is a promising therapeutic alternative.


Asunto(s)
Anomalías Múltiples , Anomalías Múltiples/diagnóstico , Anomalías Múltiples/terapia , Encéfalo/anomalías , Niño , Anomalías del Ojo/diagnóstico , Anomalías del Ojo/terapia , Femenino , Neoplasias de Cabeza y Cuello/diagnóstico , Neoplasias de Cabeza y Cuello/terapia , Cardiopatías Congénitas/diagnóstico , Cardiopatías Congénitas/terapia , Hemangioma/diagnóstico , Hemangioma/terapia , Humanos , Lactante , Malformaciones Arteriovenosas Intracraneales/diagnóstico , Malformaciones Arteriovenosas Intracraneales/terapia , Masculino , Fenotipo , Estudios Retrospectivos , Síndrome
10.
Actas Dermosifiliogr (Engl Ed) ; 111(10): 852-860, 2020 Dec.
Artículo en Inglés, Español | MEDLINE | ID: mdl-32946805

RESUMEN

INTRODUCTION: The COVID-19 pandemic outbreak introduced dramatic changes in all our lives, daily practice, and medical conferences. In search of a tool to spread dermatologic knowledge during confinement, an online medical meeting was held on April 25th to 26th, 2020. In this study, we aimed to assess the characteristics, opinion and satisfaction of the attendees to a free-of-charge online congress. Secondarily, we intended to explain how this meeting was prepared. MATERIAL AND METHODS: Online survey administered to the attendees to an online congress organised via the Telegram® Messenger App. Its organisation and planning, which needed no financial support and was done by volunteer organisers, moderators and speakers, is described step by step. RESULTS: The satisfaction of both speakers and attendees was very high. All participants considered that this format had a great present and future, and most of them rated it as superior to regular face-to-face meetings. Female gender and predominantly private practice favoured this opinion. DISCUSSION: The COVID-19 pandemic has forced the cancellation of most scientific gatherings. This has been seen by some authors as an excellent opportunity, encouraging medical societies and organisations to lead the change to virtual meetings. Although confinement did not allow real contact, our online meeting showed it was possible to ensure interaction and participation between attendees, moderators and speakers. Dermatologists enjoyed some dermatologic science, even despite the extraordinary circumstances disrupting their daily clinical practice. Most of them felt they were participating in something new and compelling that many felt superior to traditional meetings.


Asunto(s)
COVID-19/epidemiología , Congresos como Asunto/organización & administración , Dermatología , SARS-CoV-2 , Encuestas y Cuestionarios , Comunicación por Videoconferencia/organización & administración , Adulto , Anciano , Dermatólogos/estadística & datos numéricos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pandemias , Satisfacción Personal , Distanciamiento Físico
11.
Actas dermo-sifiliogr. (Ed. impr.) ; 113(8): 804-807, sept. 2022. tab
Artículo en Español | IBECS (España) | ID: ibc-208309

RESUMEN

Las complicaciones oftalmológicas en las cirugías dermatológicas son poco frecuentes. A pesar de ello, todo cirujano debe tener un conocimiento básico del reconocimiento, la prevención y el tratamiento de las cuatro complicaciones que se abordan en este artículo incluido en la serie «Seguridad en procedimientos dermatológicos». La primera complicación a tratar es el daño ocular por irritantes químicos, una situación habitual dadas las sustancias irritantes empleadas en quirófano y las localizaciones anatómicas donde se puede producir la intervención (región ciliar, región palpebral…). En segundo lugar, se aborda el daño ocular por láser, una complicación donde la prevención (utilización de gafas o lentillas protectoras) a lo largo de toda la intervención es esencial. Otra complicación a tener en cuenta debido a la proximidad de algunas intervenciones quirúrgicas al globo ocular es la punción traumática accidental. En cuarto y último lugar, se abordará el vasoespasmo o embolismo arterial retiniano por fármacos o materiales de relleno. Dicha complicación es infrecuente, pero es recomendable saber reconocerla para realizar un tratamiento precoz evitando una situación de ceguera permanente (AU)


Ophthalmological complications are uncommon in dermatologic surgery. Nonetheless, all surgeons should know the basics of recognizing, preventing, and treating the 4 complications addressed in this article from the series ‘Safety in Dermatologic Procedures’. The first complication that surgeons should be familiar with is eye damage due to chemical irritants. This is a common complication in operating rooms given the presence of irritant substances and the performance of procedures in the eyebrow and eyelid region. The second complication is laser-induced eye damage. In this case, eye protection with safety glasses or eye caps is crucial. The third complication is accidental eyeball perforation, which can occur during certain surgical procedures. The fourth and final complication is retinal artery vasospasm or embolism due to drugs or filler materials. This complication is rare but important to recognize, as early treatment can prevent permanent blindness (AU)


Asunto(s)
Humanos , Fármacos Dermatológicos/efectos adversos , Procedimientos Quirúrgicos Dermatologicos/efectos adversos , Técnicas Cosméticas/efectos adversos , Lesiones Oculares/etiología , Lesiones Oculares/prevención & control , Oftalmopatías/etiología , Oftalmopatías/prevención & control , Índice de Severidad de la Enfermedad
12.
Actas dermo-sifiliogr. (Ed. impr.) ; 113(8): t804-t807, sept. 2022. tab
Artículo en Inglés | IBECS (España) | ID: ibc-208310

RESUMEN

Ophthalmological complications are uncommon in dermatologic surgery. Nonetheless, all surgeons should know the basics of recognizing, preventing, and treating the 4 complications addressed in this article from the series ‘Safety in Dermatologic Procedures’. The first complication that surgeons should be familiar with is eye damage due to chemical irritants. This is a common complication in operating rooms given the presence of irritant substances and the performance of procedures in the eyebrow and eyelid region. The second complication is laser-induced eye damage. In this case, eye protection with safety glasses or eye caps is crucial. The third complication is accidental eyeball perforation, which can occur during certain surgical procedures. The fourth and final complication is retinal artery vasospasm or embolism due to drugs or filler materials. This complication is rare but important to recognize, as early treatment can prevent permanent blindness (AU)


Las complicaciones oftalmológicas en las cirugías dermatológicas son poco frecuentes. A pesar de ello, todo cirujano debe tener un conocimiento básico del reconocimiento, la prevención y el tratamiento de las cuatro complicaciones que se abordan en este artículo incluido en la serie «Seguridad en procedimientos dermatológicos». La primera complicación a tratar es el daño ocular por irritantes químicos, una situación habitual dadas las sustancias irritantes empleadas en quirófano y las localizaciones anatómicas donde se puede producir la intervención (región ciliar, región palpebral…). En segundo lugar, se aborda el daño ocular por láser, una complicación donde la prevención (utilización de gafas o lentillas protectoras) a lo largo de toda la intervención es esencial. Otra complicación a tener en cuenta debido a la proximidad de algunas intervenciones quirúrgicas al globo ocular es la punción traumática accidental. En cuarto y último lugar, se abordará el vasoespasmo o embolismo arterial retiniano por fármacos o materiales de relleno. Dicha complicación es infrecuente, pero es recomendable saber reconocerla para realizar un tratamiento precoz evitando una situación de ceguera permanente (AU)


Asunto(s)
Humanos , Fármacos Dermatológicos/efectos adversos , Procedimientos Quirúrgicos Dermatologicos/efectos adversos , Técnicas Cosméticas/efectos adversos , Lesiones Oculares/etiología , Lesiones Oculares/prevención & control , Oftalmopatías/etiología , Oftalmopatías/prevención & control , Índice de Severidad de la Enfermedad
16.
An Pediatr (Barc) ; 83(6): 397-403, 2015 Dec.
Artículo en Español | MEDLINE | ID: mdl-25732781

RESUMEN

INTRODUCTION: In recent years, the increasing demand for dermatological consultations in the Emergency department has resulted in the publication of a variety of studies on this subject. However, most of them deal with the general population, without taking into account the changes in frequencies found in young children (ages 0-14). OBJECTIVES: To determine the frequency of various dermatological diagnoses made by the on-call paediatrician in the Emergency Department, and after referral to Paediatric Dermatology. MATERIAL AND METHODS: Firstly, a descriptive retrospective study was performed that included all patients aged between 0 and 14 years old who were seen after being referred to the emergency paediatric dermatologist by the on-call paediatrician from June 2010 to December 2013. Secondly, an analytical study was carried by calculating the kappa index calculus, in order to establish the diagnostic concordance between the emergency paediatrician and the paediatric dermatologist. RESULTS: A total of 861 patients, with a mean age of 4.5 years were included. More than half of the skin disorders analysed were eczema (27%) and infections (26%). The 5 main diagnoses were: atopic dermatitis (16%), acute prurigo simplex (5%), tinea (5%), pyogenic granuloma (4%), and molluscum contagiosum (4%). Additional tests were only required in 16% of the cases. The kappa index obtained was 0.206 (95% CI: 0.170-0.241). CONCLUSIONS: The dermatology consultations in the Emergency Department were shown to be frequent and mostly involved minor diseases. Collaboration between paediatricians and dermatologists resulted in a high treatment success rate, leading to a low percentage of additional tests required and a high rate of discharges.


Asunto(s)
Dermatología/estadística & datos numéricos , Urgencias Médicas , Enfermedades de la Piel/diagnóstico , Centros de Atención Terciaria , Adolescente , Niño , Preescolar , Servicio de Urgencia en Hospital , Humanos , Lactante , Recién Nacido , Derivación y Consulta , Estudios Retrospectivos
17.
Actas dermo-sifiliogr. (Ed. impr.) ; 111(10): 852-860, dic. 2020. tab, ilus
Artículo en Español | IBECS (España) | ID: ibc-193096

RESUMEN

INTRODUCCIÓN: La pandemia de COVID-19 introdujo cambios drásticos en nuestras vidas. Tratando de encontrar una herramienta adecuada para la formación y el debate dermatológico durante el confinamiento, se celebró un congreso médico on-line durante los días 25 y 26 de abril del 2020. El objetivo del presente estudio fue evaluar las características, la opinión y el grado de satisfacción de los asistentes a dicho congreso. En segundo lugar, se buscó explicar cómo se organizó este formato de reunión. MATERIAL Y MÉTODOS: Se entregó un cuestionario a los asistentes a un congreso on-line realizado a través de la aplicación Telegram® Messenger App. Se describió paso a paso su organización y planificación. No se necesitó apoyo financiero, ya que fue realizado de manera voluntaria. RESULTADOS: El grado de satisfacción tanto de los ponentes como de los asistentes fue muy elevado. Todos los participantes consideraron que este formato tenía un gran presente y futuro. La mayoría lo calificó como superior a las reuniones presenciales tradicionales. Ser del sexo femenino y tener una práctica clínica predominantemente privada favorecieron esta opinión. DISCUSIÓN: La pandemia obligó a cancelar la mayoría de las reuniones científicas presenciales. Esto fue visto por algunos autores como una excelente oportunidad para mejorar y liderar el cambio a las reuniones virtuales. Aunque el confinamiento no permitió un contacto real, nuestra reunión demostró que era posible asegurar la interacción entre los participantes. Los dermatólogos pudieron participar en una actividad formativa a pesar de que debido a las circunstancias se interrumpiera su actividad práctica diaria. La mayoría de los asistentes tuvieron la sensación de que esta era una actividad nueva y atractiva, que superaba incluso a las reuniones presenciales tradicionales


INTRODUCTION: The COVID-19 pandemic outbreak introduced dramatic changes in all our lives, daily practice, and medical conferences. In search of a tool to spread dermatologic knowledge during confinement, an online medical meeting was held on April 25th to 26th, 2020. In this study, we aimed to assess the characteristics, opinion and satisfaction of the attendees to a free-of-charge online congress. Secondarily, we intended to explain how this meeting was prepared. METHODS: Online survey administered to the attendees to an online congress organised via the Telegram® Messenger App. Its organisation and planning, which needed no financial support and was done by volunteer organisers, moderators and speakers, is described step by step. RESULTS: The satisfaction of both speakers and attendees was very high. All participants considered that this format had a great present and future, and most of them rated it as superior to regular face-to-face meetings. Female gender and predominantly private practice favoured this opinion. DISCUSSION: The COVID-19 pandemic has forced the cancellation of most scientific gatherings. This has been seen by some authors as an excellent opportunity, encouraging medical societies and organisations to lead the change to virtual meetings. Although confinement did not allow real contact, our online meeting showed it was possible to ensure interaction and participation between attendees, moderators and speakers. Dermatologists enjoyed some dermatologic science, even despite the extraordinary circumstances disrupting their daily clinical practice. Most of them felt they were participating in something new and compelling that many felt superior to traditional meetings


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Congresos como Asunto/organización & administración , Acceso a Internet , Cuarentena , Infecciones por Coronavirus , Pandemias , Sistemas en Línea , Comunicación y Divulgación Científica , Dermatología , Redes Sociales en Línea , Encuestas y Cuestionarios
18.
Pediatr Pulmonol ; 49(3): E78-81, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24136903

RESUMEN

Churg-Strauss syndrome (CSS) is an anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis; it is extremely rare in childhood and defined according to the Chapel-Hill Consensus as an eosinophil-rich and granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small to medium-sized vessels. Children commonly have a history of asthma and sinusitis whilst clinical presentation typically involves pulmonary tract and less frequently skin, heart, gastrointestinal tract, and peripheral nerves. Cardiopulmonary disease is higher in children and prognosis is worse. It is associated with significant eosinophilia and raised serum IgE-levels. ANCA are only found in 25% of childhood cases. Here we report the case of a 10-year-old girl who presented to us with vomiting, abdominal pain, and weight loss, paresthesias of lower extremities and breathlessness as well as a history of asthma, sinusitis and allergic rhinitis. She was treated with corticosteroids, cyclophosphamide, intravenous immunoglobulin, mycophenolate mofetil (MMF), and rituximab. However, remission was only achieved after initiation of omalizumab therapy, a recombinant humanized anti-IgE antibody. To the best of our knowledge this is the first pediatric patient suffering from CSS successfully managed with adjuvant anti-IgE therapy resulting in the control of respiratory as well as gastrointestinal symptoms.


Asunto(s)
Anticuerpos Antiidiotipos/uso terapéutico , Anticuerpos Monoclonales Humanizados/uso terapéutico , Síndrome de Churg-Strauss/tratamiento farmacológico , Inmunomodulación , Pulmón/diagnóstico por imagen , Derrame Pericárdico/diagnóstico por imagen , Piel/patología , Niño , Síndrome de Churg-Strauss/complicaciones , Síndrome de Churg-Strauss/diagnóstico , Femenino , Humanos , Omalizumab , Derrame Pericárdico/etiología , Radiografía , Resultado del Tratamiento , Ultrasonografía
20.
An. pediatr. (2003. Ed. impr.) ; 83(6): 397-403, dic. 2015. tab, graf
Artículo en Español | IBECS (España) | ID: ibc-146519

RESUMEN

INTRODUCCIÓN: En los últimos años, la elevada demanda de asistencia en los servicios de urgencias por enfermedad cutánea ha motivado la realización de diversos estudios al respecto. Sin embargo, la mayoría están referidos a población general, sin tener en cuenta las modificaciones en las frecuencias de las enfermedades que se producen en edad pediátrica. OBJETIVOS: Determinar la frecuencia de los distintos diagnósticos dermatológicos derivados por el pediatra de guardia y atendidos en la consulta de dermatología pediátrica urgente. MATERIAL Y MÉTODOS: Estudio retrospectivo descriptivo que incluyó todos los pacientes de 0 a 14 años atendidos tras citación por el pediatra de guardia en las consultas de dermatología infantil urgente desde junio de 2010 hasta diciembre de 2013. En segundo lugar, se realizó un estudio analítico que consistía en el cálculo del índice kappa para establecer la concordancia diagnóstica entre el diagnóstico del pediatra de Urgencias y el de Dermatología. RESULTADOS: Se atendió a un total de 861 pacientes con una edad media de 4,5 años. Más de la mitad de toda la enfermedad atendida se debió a eccemas (27%) e infecciones (26%). Los 5 diagnósticos principales fueron: dermatitis atópica (16%), prurigo simple agudo (5%), tiña (5%), granuloma piógeno (4%) y molluscum contagiosum (4%). Solo en un 16% de los casos se solicitaron pruebas complementarias. El índice kappa obtenido fue de 0,206 (IC 95%: 0,170-0,241). CONCLUSIONES: Las consultas en urgencias pediátricas por motivos dermatológicos son frecuentes y gran parte está motivada por enfermedad banal. La colaboración entre pediatras y dermatólogos permitió una alta capacidad resolutiva, lo que se tradujo en un bajo porcentaje de pruebas complementarias solicitadas y un elevado número de altas directas


INTRODUCTION: In recent years, the increasing demand for dermatological consultations in the Emergency department has resulted in the publication of a variety of studies on this subject. However, most of them deal with the general population, without taking into account the changes in frequencies found in young children (ages 0-14). OBJECTIVES: To determine the frequency of various dermatological diagnoses made by the on-call paediatrician in the Emergency Department, and after referral to Paediatric Dermatology. MATERIAL AND METHODS: Firstly, a descriptive retrospective study was performed that included all patients aged between 0 and 14 years old who were seen after being referred to the emergency paediatric dermatologist by the on-call paediatrician from June 2010 to December 2013. Secondly, an analytical study was carried by calculating the kappa index calculus, in order to establish the diagnostic concordance between the emergency paediatrician and the paediatric dermatologist. RESULTS: A total of 861 patients, with a mean age of 4.5 years were included. More than half of the skin disorders analysed were eczema (27%) and infections (26%). The 5 main diagnoses were: atopic dermatitis (16%), acute prurigo simplex (5%), tinea (5%), pyogenic granuloma (4%), and molluscum contagiosum (4%). Additional tests were only required in 16% of the cases. The kappa index obtained was 0.206 (95% CI: 0.170-0.241). CONCLUSIONS: The dermatology consultations in the Emergency Department were shown to be frequent and mostly involved minor diseases. Collaboration between paediatricians and dermatologists resulted in a high treatment success rate, leading to a low percentage of additional tests required and a high rate of discharges


Asunto(s)
Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Enfermedades de la Piel/diagnóstico , Enfermedades de la Piel/epidemiología , Urgencias Médicas , Servicio de Urgencia en Hospital , Hospitales Pediátricos , Monitoreo Epidemiológico/tendencias , Estudios Retrospectivos , Dermatología , España/epidemiología
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