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J Pak Med Assoc ; 69(2): 244-245, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30804592

RESUMEN

Patients with end-stage renal disease (ESRD) are immunocompromised and are more at risk to develop and acquire Mycobacterium tuberculosis (MTB) infection. However, risk assessment is uncertain. The objective of current research was to study the frequency of MTB infection in ESRD patients . For this purpose, bronchoalveolar lavage (BAL) samples were evaluated for the presence of MTB by using GeneXpert®MTB/RIF test. We analysed 350 clinical samples of BAL collected from a tertiary care hospital in Pakistan, from September, 2015 to July, 2016. We performed the GeneXpert®test on each sample. According to our results prevalence of MTB was observed in 1.7% of bronchoalveolar lavage (BAL) samples taken from patients with chronic kidney diseases. All the positive samples were susceptible to rifampicin. There is a low prevalence of MTB infec tion (pulmonar y tuberculosis) in patients with chronic kidney disease in our setup. Suspected patients can be diagnosed by using GeneXpert®MTB/RIF testing on bronchoalveolar lavage samples.


Asunto(s)
Líquido del Lavado Bronquioalveolar/microbiología , Fallo Renal Crónico , Pruebas de Sensibilidad Microbiana/métodos , Mycobacterium tuberculosis , Rifampin/farmacología , Tuberculosis , Antibióticos Antituberculosos/farmacología , Femenino , Humanos , Huésped Inmunocomprometido , Fallo Renal Crónico/complicaciones , Fallo Renal Crónico/epidemiología , Fallo Renal Crónico/inmunología , Masculino , Persona de Mediana Edad , Mycobacterium tuberculosis/efectos de los fármacos , Mycobacterium tuberculosis/aislamiento & purificación , Pakistán/epidemiología , Prevalencia , Medición de Riesgo , Centros de Atención Terciaria/estadística & datos numéricos , Tuberculosis/diagnóstico , Tuberculosis/epidemiología , Tuberculosis/etiología
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