Detalles de la búsqueda
1.
Translational Modeling Strategies for Orally Administered Drug Products: Academic, Industrial and Regulatory Perspectives.
Pharm Res
; 37(6): 95, 2020 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32405699
2.
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations.
Pharm Res
; 37(12): 245, 2020 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33215336
3.
Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism.
Drug Metab Dispos
; 47(8): 818-831, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31101678
4.
Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 2. Rational Bioavailability Design by Global Sensitivity Analysis To Identify Properties Affecting Bioavailability.
Mol Pharm
; 15(3): 831-839, 2018 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29337562
5.
Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 1. Evaluation and Adaptation of GastroPlus To Predict Bioavailability of Medchem Series.
Mol Pharm
; 15(3): 821-830, 2018 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29337578
6.
The Prediction of the Relative Importance of CYP3A/P-glycoprotein to the Nonlinear Intestinal Absorption of Drugs by Advanced Compartmental Absorption and Transit Model.
Drug Metab Dispos
; 44(11): 1808-1818, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27538919
7.
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Metabolism in Pregnant Subjects and Fetuses.
Pharmaceutics
; 16(1)2024 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38258106
8.
In silico modeling for the nonlinear absorption kinetics of UK-343,664: a P-gp and CYP3A4 substrate.
Mol Pharm
; 9(3): 492-504, 2012 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22264132
9.
Provisional biopharmaceutical classification of some common herbs used in Western medicine.
Mol Pharm
; 9(4): 815-22, 2012 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22352942
10.
Perspective on a chemistry classification system for AI-assisted formulation development.
J Control Release
; 352: 833-839, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36334857
11.
Predicting Pharmacokinetics of Multisource Acyclovir Oral Products Through Physiologically Based Biopharmaceutics Modeling.
J Pharm Sci
; 111(1): 262-273, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34678271
12.
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus.
AAPS J
; 23(4): 89, 2021 06 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34169370
13.
PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates.
Pharmaceutics
; 13(9)2021 Aug 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34575401
14.
Predicting the effect of fed-state intestinal contents on drug dissolution.
Pharm Res
; 27(12): 2646-56, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20963629
15.
A combined in vitro in-silico approach to predict the oral bioavailability of borderline BCS Class II/IV weak base albendazole and its main metabolite albendazole sulfoxide.
Eur J Pharm Sci
; 155: 105552, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32937212
16.
Current status and future opportunities for incorporation of dissolution data in PBPK modeling for pharmaceutical development and regulatory applications: OrBiTo consortium commentary.
Eur J Pharm Biopharm
; 155: 55-68, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32781025
17.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Eur J Pharm Biopharm
; 156: 50-63, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32805361
18.
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Pharm Res
; 26(10): 2358-66, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19685173
19.
Application of a Dynamic Fluid and pH Model to Simulate Intraluminal and Systemic Concentrations of a Weak Base in GastroPlus™.
J Pharm Sci
; 108(1): 305-315, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30395828
20.
The Irrelevance of In Vitro Dissolution in Setting Product Specifications for Drugs Like Dextromethorphan That are Subject to Lysosomal Trapping.
J Pharm Sci
; 108(1): 268-278, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30316900