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1.
Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.
Altern Lab Anim
; 52(2): 117-131, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38235727
2.
Increased Contractile Response to Noradrenaline Induced By Factors Associated with the Metabolic Syndrome in Cultured Small Mesenteric Arteries.
Pharmacology
; 97(1-2): 48-56, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26587661
3.
Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs.
Pflugers Arch
; 466(12): 2167-76, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24590510
4.
The evolving role of investigative toxicology in the pharmaceutical industry.
Nat Rev Drug Discov
; 22(4): 317-335, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36781957
5.
Effect of ageing on the passive and active tension and pharmacodynamic characteristics of rat coronary arteries: age-dependent increase in sensitivity to 5-HT and K+.
Pharmacology
; 90(3-4): 160-8, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22922218
6.
Early onset inflammation in pre-insulin-resistant diet-induced obese rats does not affect the vasoreactivity of isolated small mesenteric arteries.
Pharmacology
; 90(3-4): 125-32, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22832366
7.
Optimizing drug discovery by Investigative Toxicology: Current and future trends.
ALTEX
; 36(2): 289-313, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30570669
8.
Lipopolysaccharides, but not Angiotensin ll, lnduces Direct Pro-lnflammatory Effects in Cultured Mouse Arteries and Human Endothelial and Vascular Smooth Muscle Cells.
Basic Clin Pharmacol Toxicol
; 120(4): 335-347, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27813367
9.
New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells.
J Med Chem
; 49(14): 4127-39, 2006 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16821773
10.
Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance-sized arteries.
Pharmacol Res Perspect
; 3(6): e00200, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27022471
11.
Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.
J Med Chem
; 47(12): 3202-11, 2004 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-15163199
12.
6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.
J Med Chem
; 45(19): 4171-87, 2002 Sep 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-12213059
13.
Characterization of capsaicin induced responses in mice vas deferens: evidence of CGRP uptake.
Eur J Pharmacol
; 667(1-3): 375-82, 2011 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21741970
14.
Medicines combinations options and regulatory hurdles.
Eur J Pharm Sci
; 49(4): 659-63, 2013 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23643740
15.
Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels.
Bioorg Med Chem
; 13(1): 141-55, 2005 Jan 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-15582459
16.
Synthesis and biological activity of 3,3-diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells.
Bioorg Med Chem
; 11(6): 931-40, 2003 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-12614878
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